Search Results (1,240)

This study investigated real-time polymerisation kinetics and mechanical properties under accelerated ageing of novel universal bulk-fill composites incorporating reversible addition–fragmentation chain transfer (RAFT) agent ß-allyl sulfone, designed for anterior and posterior applications. Five bulk-fill composites were tested: Tetric Plus Fill and Tetric Plus Flow (new universal composites); their predecessors, Tetric PowerFill and Tetric PowerFlow (Ivoclar); and RAFT-free Ecosite Bulk Fill (DMG). Specimens were polymerised for 3 s (~3000 mW/cm²), 10 s (~1200 mW/cm²), or 20 s (~1200 mW/cm²). Degree of conversion (DC) was monitored during and after curing, with mechanical testing after 24 h and after thermal cycling. DC and maximum polymerisation rate at 4 mm depth were significantly lower than at 0.1 mm for all materials and curing times. Three-second curing accelerated the polymerisation rate at both depths. Except for Ecosite cured for 3 or 10 s as RAFT-free material, DC ratios at 4 mm exceeded 80% of surface values. Tetric Plus Fill and Ecosite exhibited the highest flexural strength after 24 h, while PowerFill and Ecosite showed the highest flexural modulus at 24 h and after thermal cycling. Rapid curing did not compromise mechanical properties after 24 h, except for PowerFlow, the composite with the lowest filler vol%, but negatively affected both flowable composites after ageing. Thermal cycling reduced flexural strength in most tested conditions, but all materials and curing conditions more than satisfied the ISO 4049 requirements. The new simplified universal composite Plus Fill has a higher DC and improved polymerisation kinetics compared to its predecessor, PowerFill. Rapid curing is not recommended for the material without RAFT agents. Full article

This study evaluates the reliability of calibration constants for heat flux meters (HFMs) using a secondary standard under controlled thermal conditions provided by an ISO 5660-1 cone heater. Six HFMs (three new and three previously used) were examined by comparing manufacturer-provided (MFG) and secondary-standard-based (SEC) calibration constants. The bias between the MFG and SEC calibration constants varied substantially depending on the manufacturer, calibration method, service history, and the coating condition of the sensing surface. When the Bland–Altman limits of agreement were defined with the new HFMs as the reference, an HFM from a different manufacturer or calibrated by a different method was found to fall outside these limits. Although the absolute accuracy of the secondary-standard HFM has not been independently validated, the approach using the cone heater is practical for field implementation in terms of equipment accessibility, cost, and operational simplicity. Recalibration against the same secondary-standard prior to use is recommended to ensure repeatability and reproducibility across experiments and institutions. Full article

Activity-based protein profiling (ABPP) has emerged as a powerful chemical proteomics approach for profiling active amino acid residues, mapping functional proteins, and guiding covalent drug development in complex biological systems. Recent methodological advances have produced several novel formats, including tandem orthogonal proteolysis-ABPP (TOP-ABPP), isotopic tandem orthogonal proteolysis-ABPP (IsoTOP-ABPP), and competitive IsoTOP-ABPP, enabling broader target identification and quantitative analysis for varied experimental purposes. In parallel, chemical probe design has evolved to selectively target specific amino acid residues, such as cysteine (Cys), lysine (Lys), and histidine (His), and to incorporate photoaffinity labeling (PAL) functionalities for capturing transient or weak protein-ligand interactions. Additionally, the integration of cleavable linkers with diverse cleavage mechanisms, including acid/base-mediated, redox-mediated, and photo irradiation mechanisms, has enhanced probe versatility and downstream analytical workflows. This review summarizes recent advances in ABPP methodologies and the design of activity-based probes and PAL probes, emphasizing their implications for future work in chemical biology. Full article

Liepāja Lake, a Natura 2000 protected area and one of the largest coastal freshwater bodies in Latvia, has been historically influenced by urbanization, diffuse agricultural inputs, and legacy contamination from metallurgy and ship-repair industries. Comprehensive, spatially explicit data on its sediment and water chemistry were previously lacking. The dataset used in this study provides an openly accessible record of major and trace element concentrations in surface sediments and surface waters collected during the 2024 field campaign. Sampling sites were distributed across northern, central, and southern zones to capture gradients in anthropogenic pressure and natural variability. Water samples were filtered and acidified following ISO 15587-2:2002, while sediments were homogenized, sieved, and digested following EPA 3051a. Both matrices were analyzed using Inductively Coupled Plasma Mass Spectrometry (ICP-MS, Agilent 8900 ICP-QQQ) with multi-element calibration traceable to NIST standards. The dataset comprises 31 analytes (Li–Bi) with paired standard deviation values, reported in mg kg^–1 (sediments) and µg L^–1 (water). Rigorous validation included certified reference materials, duplicates, blanks, and statistical outlier screening. The resulting data form a reliable geochemical baseline for assessing pollution sources, quantifying spatial heterogeneity, and supporting future monitoring, modeling, and restoration efforts in climate-sensitive Baltic coastal lakes. Full article

With the increasing demand for sustainable building materials, it has become essential to identify sustainable alternatives to conventional sound absorbers, particularly in the context of waste reduction and the circular economy. The aim of this study was to compile and describe a structured dataset of sound absorption coefficients for laboratory-produced panels made from recycled textile materials. Five types of panels were developed using cotton, polyester, wool, linen, and a mixed composition of textiles. A biopolymer binder was applied to ensure structural stability of the materials. Following careful sorting, shredding, and homogenization of the textile waste, test specimens were prepared and examined under controlled laboratory conditions. The sound absorption coefficients were measured using an AFD 1000 impedance tube in accordance with the ISO 10534-2 standard, across a frequency range from 6.25 to 6393.75 Hz. For each material, three repeated measurements were performed, and mean values were calculated to ensure accuracy and reliability. The resulting dataset contains structured values of sound absorption coefficients, which can be applied in building acoustics modeling, comparative studies with conventional insulation materials, and the development of new sustainable products. In addition, the data can be used in educational contexts and machine learning applications to predict the acoustic properties of recycled textile composites. Full article

This study investigates the optimization of sol–silicate façade coatings modified with colloidal silica and a silane-based hydrophobizing additive to enhance hydrophobicity while maintaining a high water-vapor transmission rate (V). The effects of the binder ratio between potassium water glass (WG) and colloidal silica (CS), the type of colloidal silica (unmodified or epoxy-silanized), and the concentration of the hydrophobizing additive (HA) were systematically evaluated. Water-vapor transmission was determined according to EN ISO 7783, and surface wettability was measured before and after accelerated UV-A aging. Dynamic viscosity was monitored for two years to assess long-term storage stability. The optimized formulation contained 7 wt % potassium water glass, 15 wt % colloidal silica, and 1 wt % hydrophobizing additive. It exhibited stable viscosity over time (≈19,000 mPa·s after six months), high water-vapor transmission (V > 6700 g·m⁻²·d⁻¹, class V1), and an initial contact angle of 118°, which decreased only moderately after UV-A exposure. Coatings containing epoxy-silanized colloidal silica showed slightly lower transmission but still remained within the high V range suitable for vapor-open façade systems. The results confirm that balanced sol–silicate systems can combine durable hydrophobicity with long-term rheological and functional stability. Full article

Calcium silicate-based cement is commonly used for bone repair and regeneration. Current research focuses on developing innovative antibacterial materials with radiopacity, which is essential for ensuring successful clinical outcomes in procedures like vertebroplasty and endodontic treatments. Strontium (Sr) has emerged as a powerful additive, stimulating bone formation and inhibiting bone resorption. In this study, we evaluated the impact of varying levels of Sr—5, 10, and 20 mol% (designated as CSSr5, CSSr10, and CSSr20) on critical attributes of bone cement, including radiopacity, setting time, in vitro bioactivity, antibacterial efficacy, and osteogenic activity. The findings indicated that as the Sr content increased, the setting time and radiopacity of the cement increased. Remarkably, the cement formulations containing over 10 mol% Sr achieved radiopacity values surpassing the 3 mm aluminum threshold mandated by ISO 6876:2001 standards. Furthermore, incorporating Sr significantly improved MG63 cell attachment, proliferation, differentiation, and mineralization, while also boosting antibacterial properties in a dose-dependent manner. After 48 h of inoculation with E. coli or S. aureus, the CSSr10 and CSSr20 cements showed a bacteriostatic ratio exceeding 1.7 or 2 times that of the control without Sr. In conclusion, the CSSr10 cement could be a promising bone filler, exhibiting favorable setting time, radiopacity, antibacterial ability, and osteogenic activity. Full article

In this study, a novel activated carbon (AC) (AC-Ba(OH)₂) was synthesized through a three-step process (including hydrothermal carbonization (at 250 °C), alkali activation by Ba(OH)₂, and pyrolysis (at 850 °C)), from Plane tree fruits (PTFs). By using various experimental methods for material characterization, it was established that the resulting material possesses a variety of oxygen functional groups, rich in alkaline earth oxides (BaO/CaO), SiO₂, consisting of graphitized carbon with graphene structures. A detailed kinetic and thermodynamic analysis of AC-Ba(OH)₂ thermal restoring was also carried out. Thermodynamic analysis revealed the existence of a true thermodynamic compensation effect (TCE) during restoration. Restoration was controlled by entropy, where experimental temperatures are above the iso-entropic temperature, i.e., the temperature where contributions of enthalpy and entropy to activation free energy are balanced. Kinetic modeling has shown that restoration allows carbon material to be significantly modified by removing oxygen-containing groups via diffusion, changing active sites on the surface, and preparing material for catalyst support. CaO and SiO₂ act as catalysts, while BaO alters graphene surface properties. Isothermal prediction tests have shown an extremely high long-term stability of modified AC-Ba(OH)₂, supporting an elevated activity, selectivity, and lifetime, as well. The restoring process resulted in an energy consumption of 0.762 kWh, which is equivalent to the reactivation of AC with a lower specific surface area. Manufactured AC and its thermally modified counterpart can be used as both a catalyst support and catalyst for reforming processes, such as methanol synthesis, biogas purification, and dry reforming of methane. Full article

Andean high-altitude ecosystems are critical to sustaining biodiversity, agriculture, and the livelihoods of indigenous populations. However, accelerating glacier retreat, irregular precipitation, and intensive water use have exacerbated ecosystem degradation and water insecurity. This study conducts a scoping review (PRISMA-ScR) of peer-reviewed and grey literature (2000–2025) to examine how water footprint (WF) management through its blue, green, and gray components can be operationalized within an Integrated Water Resource Management (IWRM) and Human Rights-Based Approach (HRBA) to ensure equitable access and ecological sustainability in the Andes. Quantitative synthesis from 72 sources shows that agricultural withdrawals account for over 78% of total blue-water use, while glacier-fed runoff has declined by 32% over the past two decades. Empirical evidence from Peru, Ecuador, and Bolivia demonstrates that integrating indigenous irrigation systems with modern efficiency technologies reduces consumptive water use by up to 25% and enhances wetland biodiversity indices by 15–20%. These findings support the development of an Integrated Water-Biodiversity-Rights Framework (IWBRF) that links WF indicators (WFAM and ISO 14046) with ecosystem integrity and social equity metrics. The study advances theory by clarifying how WF indicators inform rather than replace IWRM and HRBA decision processes, offering a practical model for achieving water justice, biodiversity protection, and climate resilience in fragile Andean ecosystems. Full article

The significant advancement in additive technologies has made it possible to manufacture metal components in diverse shapes and sizes. Despite this progress, numerous processes and phenomena, along with the implications of producing components layer by layer on their performance under stress, remain inadequately explored. These factors not only affect microstructure but subsequently also the mechanical properties. The positioning of objects within the 3D printer’s workspace can thus significantly play a crucial role in their operational functionality, reliability, and safety of the equipment in an application. This article studies anisotropic properties and the influence of the printing orientation of aluminum alloy (AlSi10Mg) cylindrical tensile samples fabricated through an additive approach on their mechanical properties under tensile loading. Tensile testing of specimens covering seven different spatial orientations in the workspace of a 3D printing machine was performed according to ISO 6892-1 international standard. Minimum and maximum tensile properties (yield and ultimate tensile strength) have been observed in Y-sample and X-sample series, respectively. In contrast, elastic modulus of the 3D printed specimens was minimal for X-sample series, and maximal for Y-sample series. Fracture surfaces of the samples in seven basic spatial orientations were evaluated in synergy with the mechanical testing results determined by optical, electron microscopy, and electron backscatter diffraction (EBSD) textural analysis to find correlation between the strength of the samples and the orientation of grains, their size and morphology. Furthermore, thermodynamic and Scheil–Gulliver simulation has been employed in order to explain the formation of intermetallic phases during additive manufacturing and further justifying observations in microstructure and mechanical properties. The disparity in texture intensity between these regions for samples Y(3) is likely responsible for localized mechanical incompatibilities and strain heterogeneity, resulting in preferential crack paths and reduced mechanical strength compared to the sample Z(3), which presented a more randomized orientation distribution with less distinguishable texture zones, enabling better strain accommodation and more uniform plastic deformation, which correlates with its higher tensile and yield strength. Full article

Background: Idiopathic macular holes (MHs) are typically treated with pars plana vitrectomy and internal limiting membrane (ILM) peeling. The inverted ILM flap (ILMF) technique has emerged for MHs, but long-term outcome data remain inadequately established. This study evaluates the long-term functional and anatomical outcomes of the ILMF in idiopathic MHs. Methods: We evaluated 71 consecutive eyes of patients with idiopathic MHs who underwent vitrectomy with the inverted ILMF. Follow-up duration was more than 12 months. Visual acuity was measured, and macular anatomy was monitored with optic coherence tomography (OCT). Long-term visual and anatomical outcomes were defined a priori and analyzed accordingly. Results: Final vision values showed significant improvement compared to preoperative ones, from 1.02 [Snellen Equivalent (SE), 19/200] ± 0.40 logarithm of the minimum angle of resolution (logMAR) to 0.47 (SE, 68/200) ± 0.39 logMAR (p < 0.001). The primary MH closure rates were 94.37% (67/71), while the secondary closure rate reached 97.18% (69/71). Factors associated with better final vision included smaller hole size, favorable hole stage, better preoperative vision, intact postoperative foveal microstructure and contour. The recovery of the external limiting membrane (ELM), inner and outer segment junction (IS/OS), and good foveal contour had improved to 73.4%, 40.3%, and 49.3% at one year and 80%, 71.4%, and 53.3% at three years postoperatively, respectively. Conclusions: In idiopathic MHs, the ILMF approach provides meaningful, long-term visual and microstructural recovery, especially with a favorable functional outcome and intact postoperative microstructure sustaining up to three years. Full article

In response to the International Maritime Organization (IMO)’s greenhouse gas reduction targets and the growing demand for decarbonization in the maritime sector, the development of hydrogen-fueled ship technologies has gained increasing attention. Liquid hydrogen (LH₂) is regarded as a promising marine fuel due to its high energy density per unit volume when liquefied at −253 °C, enabling large-scale storage and transportation. However, critical technical challenges remain in cryogenic storage, transfer, vaporization processes, and safety assurance. This study proposes a conceptual pre-standardization framework for land-based evaluation of LH₂ fuel tank and supply systems, supported by preliminary validation using LN₂ surrogate tests. The protocol is established through a reinterpretation of existing international and domestic standards (KGS AC111, ISO/TR 15916, CGA H-3) and adapted to Korean demonstration environments. Test items were categorized into (i) supply performance (flow and pressure), (ii) vaporization and heating performance (temperature), and (iii) safety functions, with acceptance criteria benchmarked against international guidelines. To overcome the significant safety and cost constraints of handling actual LH₂, liquid nitrogen (LN₂) was applied as a surrogate medium to enable preliminary validation under safe and practical conditions, and process simulations are proposed as a future pathway for comprehensive verification. The results highlight not only the application but also the localization and refinement of global standards into a practical protocol for small- to medium-sized ship applications. This protocol is expected to serve as a critical reference for subsequent sea trials and commercialization, thereby contributing to the advancement of eco-friendly marine fuel technologies and strengthening international competitiveness in the hydrogen powered shipping sector. Full article

Adaptive facades represent the result of a complex combination of innovative technologies, components, and materials, as well as mechanical, electronic, or digital technologies from sectors outside the construction world (technology transfer), which require a constant multidisciplinary systemic approach. Unlike traditional envelopes, adaptive facades integrate aesthetics, functionality, and energy performance within a single system. This field of research has long been the subject of study by important institutions and research groups that have identified the macro-categories of adaptive envelopes that cover the largest share of the market and have defined the first ISO standards related to dynamic shading, chromogenic envelopes, and active ventilated facades. From the state-of-the-art analysis, adaptive facade systems exhibit short response times, measurable in seconds or minutes, while medium- to long-term adaptability remains underexplored. The objective of this study is to address this gap by considering durability and circularity. Analysis of a database of 329 building envelopes reveals a predominance of short-term strategies within the environmental domain, while long-term strategies focus on material durability and resilience through system regeneration and reuse. These strategies allow for maintaining energy performance by reducing degradation. Ongoing research integrates these strategies with reusability and circularity, extending the perspective beyond the building’s service life to support sustainable lifecycle approaches. Full article

Diabetic foot ulcers (DFUs) are complex to heal and can lead to amputations and high healthcare costs. To address this, a promising alternative is the creation of electrospun fiber scaffolds for wound dressings. This study fabricated these scaffolds using a blend of natural polymers—chitosan (CTS), polyvinyl alcohol (PVA), and hyaluronic acid (HA)—along with antibacterial silver (Ag) and zinc oxide (ZnO) nanoparticles. The researchers conducted comprehensive analyses, including physicochemical, morphological, and biological assessments. The Ag structures showed potential as microbicidal agent, while the ZnO nanoparticles demonstrated photoactivity and the ability to generate reactive oxygen species (ROS) for antibacterial action. The resulting PVA-CTS-HA-Ag-ZnO scaffolds were found to be both hemocompatible and non-hemolytic, meaning they are safe for use with blood. The cytotoxicity evaluation using the ISO 10993-5 standard showed that the incorporation of CTS and HA decreased cytotoxicity of pure PVA, obtaining non-cytotoxic scaffolds (viability > 70%). Electrospun scaffolds composed with Ag-ZnO NPs in 50-50 and 70-30 ratios also maintained this biocompatibility, while the 30-70 ratio (Ag-ZnO) showed a cytotoxic effect, suggesting a ZnO concentration-dependent effect. These findings confirm that these materials are suitable for supporting skin cell regeneration, having a high potential for use as interactive dressings for treating chronic wounds. Full article

The increasing need for precise testing in battery and electronic component development has driven the demand for modular and scalable laboratory systems. This paper presents the design and initial implementation of a LabVIEW-based measurement system tailored for ISO/IEC 17025-compliant testing environments. The system’s software architecture is modular and built around a Hardware Abstraction Layer, enabling the integration of various remotely controlled instruments, such as programmable power supplies, electronic loads, and climate chambers. LabVIEW’s object-oriented programming and multi-threaded execution environment allows synchronized control and real-time data acquisition. Test procedures are defined using a JSON-based sequence structure, supporting repeatable testing. A graphical editor provides an intuitive interface for configuring test steps, ensuring ease of use. The system is designed to support future expansion, including high-speed measurement modules and parallel test execution. This solution lays the foundation for a reliable and extensible automated testing platform that aligns with modern industrial and regulatory standards. Full article