Search Results (46)

Investigating land cover patterns, changes in carbon stocks, and forecasting future conditions are essential for formulating regional sustainable development strategies and enhancing ecological and environmental quality. This study centers on Guiyang, a mountainous urban area in southwestern China, to analyze the dynamic changes in land cover and their effects on carbon stocks from 2000 to 2035. A carbon stocks assessment framework was developed using a cellular automaton-based artificial neural network model (CA-ANN), the InVEST model, and the geographical detector model to predict future land cover changes and identify the primary drivers of variations in carbon stocks. The results indicate that (1) from 2000 to 2020, impervious surfaces expanded significantly, increasing by 199.73 km². Compared to 2020, impervious surfaces are projected to increase by 1.06 km², 13.54 km², and 34.97 km² in 2025, 2030, and 2035, respectively, leading to further reductions in grassland and forest areas. (2) Over time, carbon stocks in Guiyang exhibited a general decreasing trend; spatially, carbon stocks were higher in the western and northern regions and lower in the central and southern regions. (3) The level of greenness, measured by the normalized vegetation index (NDVI), significantly influenced the spatial variation of carbon stocks in Guiyang. Changes in carbon stocks resulted from the combined effects of multiple factors, with the annual average temperature and NDVI being the most influential. These findings provide a scientific basis for advancing low-carbon development and constructing an ecological civilization in Guiyang. Full article

Urbanization always leads to increasing challenges to the groundwater resources in karst regions due to intensive land use, infrastructure development, and the rapid transmission potential of pollutants. This study proposed an improved groundwater vulnerability assessment (GVA) framework by modifying the widely used COP (Concentration of flow, Overlying layers, and Precipitation) model, through the integration of three additional indicators: urban underground rail transportation (UURT), land use and cover (LULC), and karst development (K). Guiyang, a typical urbanized karst city in southwest China, was selected as the case study. The improved COP model, namely the COPK model, showed stronger spatial differentiation and a higher Pearson correlation coefficient ($r$) with nitrate concentrations ($r$ = 0.4388) compared to the original COP model (R = 0.3689), which validates the effectiveness of the newly introduced indicators. However, both R values remained below 0.5, even after model modification, suggesting that intensive human activities play a role in influencing nitrate distribution. The pollution load index (PI) was developed based on seven types of pollution sources, and it was integrated with the COPK vulnerability index using a risk matrix approach, producing a groundwater risk map classified into five levels. Global Moran’s I analysis (0.9171 for COP model and 0.8739 for COPK model) confirmed strong and significant spatial clustering patterns for the two models. The inclusion of UURT and LULC improved the model’s sensitivity to urban-related pressures and enhanced its capacity to detect local risk zones. It is a scalable tool for groundwater risk assessment in urbanized karst areas and offers practical insights for land use planning and sustainable groundwater management. Full article

Objective: To explore the efficacy and mechanism of Coix seeds in treating herpes zoster (HZ) using an integrated computational approach. Methods: Network pharmacology, molecular docking, and machine learning were employed. Disease-related targets were collected from multiple databases, and intersection targets with Coix seed were analyzed via PPI, GO, and KEGG enrichment. A “TCM-Ingredient-Target” network was constructed using Cytoscape. Molecular docking and dynamics simulations were performed for validation. Results: Fifty-five overlapping targets were identified, with core targets including TNF, EGF, and GAPDH. Enrichment analysis revealed key pathways such as inflammation and immune regulation. Molecular docking confirmed strong binding affinity between active compounds and targets. Conclusions: This study demonstrates that Coix seed exerts anti-HZ effects through multi-target mechanisms, providing a theoretical basis for developing novel multi-pathway treatment strategies. Full article

Urban development boundaries are efficient tools for coordinating urban–rural relations and ensuring sustainable development. From 2000 to 2020, the expansion rate of the built-up area in cities and towns throughout China reached 177%, far exceeding the urban population growth rate of 96.5% in the same period. As this spatial expansion seems to continue, there is a need to intervene and control urban boundaries. We believe using the urban–rural integration perspective to set (or reset) and maintain urban development boundaries will help manage urban expansion more effectively than present methods. This research, therefore, develops an urban development boundary delineation method from a macroscopic view for China. A new model for defining boundaries was developed based on the four dimensions of urban–rural interaction: economic demand, environmental protection, urban carrying capacity, and urban development resistance. And an empirical study was conducted in Guiyang City as an example. The results show that the resultant urban boundary can provide a more comprehensive and realistic growth model than current methods, making it more applicable for controlling and fostering sustainable urban and rural development. Full article

As urbanization accelerates globally, preserving and developing historical cultural districts is increasingly critical, especially in areas with unique historical and cultural value. To understand the development of urban construction and the diachronic and spatial patterns of development, this paper focuses on Guiyang, a key transportation hub in Southwest China connected to Southeast Asia. It examines the historical districts from four representative periods: the early Ming Dynasty (1413–1420), the early Qing Dynasty (1616–1626), the Republican era (1912–1949), and the 1980s (1980–1990). Employing complex network analysis, the study investigates the changes in the connectivity characteristics of construction land and road networks. Key findings reveal: (1) Stability: The construction land networks stability decreased steadily from the early Ming period to the 1980s, whereas the road network density exhibited a wave-like decline. (2) Centrality: The construction land networks centrality decreased linearly, and the road network density exhibited a wave-like decrease. (3) Vulnerability: Both networks showed increased vulnerability, with fluctuations in the road network during the early Qing period, but generally reduced vulnerability. The analysis also indicates that changes in the connectivity of Guiyang’s historical district construction land and road networks are influenced by shifts in social structures, improvements in productivity, and the physical geography of the area. In mountainous cities with limited terrain, urban forms have transitioned from single-center aggregation to multi-center aggregation, and areas where administrative expansion is not feasible have adopted compact spatial development strategies. The application of complex network analysis has proven effective in urban spatial studies, revealing that changes in construction land and road networks reflect multifaceted internal transformations in society, politics, economy, military, and culture, significantly impacting the formation of a diverse yet unified national identity. Based on these findings, this paper offers recommendations for the planning and development of mountainous cities globally. Full article

Urban forest parks serve as significant venues for tourists’ leisure and recreation. The experiences and perceptions of tourists in these parks considerably influence their attitudes and behaviors. While numerous studies have investigated the functions and values of urban forest parks at a macro level, the mechanisms influencing tourists’ perceived values and their environmentally responsible behavior at a micro level remain under explored. This research used structural equation modeling (SEM) to test the association between tourists’ perceived values and their environmentally responsible behavior, including the mediating functions of tourists’ satisfaction and their subjective well-being. 502 valid questionnaires in total were obtained from Changpoling National Forest Park in Guiyang City, Guizhou, China, for this case study. The results show that there are some variances in the impact of the dimensions of tourists’ perceived value on environmentally responsible behavior, in which service quality, resource quality, and emotional value impose a pronounced positive effect on environmentally responsible behavior, tourism costs impose a pronounced negative effect on environmentally responsible behavior, and the activity experience does not exert a pronounced effect on environmentally responsible behavior. Satisfaction and subjective well-being have a mediating function during the process of positive influence of tourists’ perceived value on their environmentally responsible behavior and serve as partial mediators, and the significant positive influence of satisfaction on subjective well-being as well as subjective well-being on environmentally responsible behavior are verified. This research can help better explain the mechanism of the effect of tourists’ perceived value exerted on environmental responsibility behavior in nature-based tourism destinations, and also has a guiding and reference significance for the sustainable development of urban forest parks. Full article

The examination of land-use change simulations across a range of scenarios represents a pivotal research avenue for the advancement of sustainable development analysis. Nevertheless, the extant research merely categorises all building land in a land-use classification into a single category, which is unable to provide a detailed analysis of the dynamic internal spatial form of the city. This paper analyses 17 LCZ land-use types in Guiyang City in 2013 and 2022, and reclassifies them into 7 RLCZ land-use types based on the height of urban building sites. It also proposes three possible scenarios of BAU, WLC, and SPC in 2040 and simulates their land-use changes using the PLUS model. The results demonstrate that (1) the size of low-rise buildings in Guiyang has declined significantly over the past decade; (2) built-up land within cities is significantly affected by drivers such as night-time lighting, topography, elevation, and roads; (3) the SPC scenario emphasises a development pattern of land intensification and a focus on high density in urban built space. It also protects the stability of the ecosystem. The scenario can provide informative suggestions for spatial pattern changes in rapidly developing cities such as Guiyang. Full article

Guizhou is a typical mountainous province and is also one of the lowland regions in China that has attracted a population influx. Here, using population density data from 2000 to 2020 as the basic dataset and the coefficient of variation method and standard deviation ellipse analysis, we investigated the spatial characteristics across different years. The results show: Firstly, Guizhou’s population has a distinct spatial distribution, characterized by a lower population density in the southeast and a higher density in the northwest as well as an increasing polarization of population concentration toward the centers of prefecture-level cities and provincial capitals. Fluctuations in population density resemble a central siphon effect, which is particularly pronounced in the provincial capital and show a significant gravitational pull. Secondly, the coefficient of variation in population density across Guizhou’s counties is spatially divided by Guiyang, showing higher values in the east and lower values in the west. Furthermore, the ellipse of the standard deviation of population density is gradually shrinking, indicating an increasingly concentrated population distribution. Thirdly, the explanatory power of the population and socio-economic systems on the population distribution in Guizhou is significantly greater than that of the natural systems. Population distribution and migration patterns have shifted from purely “economic driven” to coexisting with “economic and comfort-oriented” trends, and there is an urgent need to improve the comfort level of public services as a typical supply, in order to boost Guizhou’s population attraction. Full article

With the recent changes in population structure and continuous urbanization, the degree of population shrinkage in mountain cities has increased, especially under the impact of the COVID-19 epidemic, and the economic development of such mountain cities has become a prominent issue. The epidemic has not only exposed the vulnerability of these cities to economic development but also aggravated the negative impact of population contraction, bringing about new challenges and pressures related to regional population development and economic resilience. This change has become an important topic in the study of mountain cities. Therefore, taking Guizhou Province as a case study, this work applies the population change rate, the entropy method, and a mediation effect model to study the spatiotemporal evolution of population shrinkage and economic resilience, and it explores how population shrinkage influences economic resilience. The results reveal the following: (1) Few counties experienced population shrinkage in Guizhou Province from 2013 to 2017, indicating a sporadic distribution pattern, whereas the degree of population shrinkage increased rapidly from 2018 to 2022, revealing an east–west symmetrical distribution pattern, with Guiyang city located on the central axis. (2) There are significant regional differences in the spatial distribution of the level of economic resilience between the two periods. Under the impact of COVID-19, from 2019 to 2022, although the overall level of economic resilience increased, the level of resilience in most counties tended to decrease. (3) Regarding the mediating effect, population shrinkage affected the level of economic resilience through general public budget expenditure, foreign trade investment, new urban employment, and GDP. The abovementioned findings are helpful for providing theoretical support and empirical guidance for the sustainable development of mountain cities in the face of population contraction, economic challenges, and promoting regional coordination. Full article

Despite enhancements in pollution control measures in southwestern China, detailed assessments of PM_2.5 dynamics following the implementation of the Clean Air Action remain limited. This study explores the PM_2.5 concentrations and their chemical compositions during the winter haze period of 2017 across four major urban centers—Chengdu, Chongqing, Guiyang, and Kunming. Significant variability in mean PM_2.5 concentrations was observed: Chengdu (71.8 μg m⁻³) and Chongqing (53.3 μg m⁻³) recorded the highest levels, substantially exceeding national air quality standards, while Guiyang and Kunming reported lower concentrations, suggestive of comparatively milder pollution. The analysis revealed that sulfate, nitrate, and ammonium (collectively referred to as SNA) constituted a substantial portion of the PM_2.5 mass—47.2% in Chengdu, 62.2% in Chongqing, 59.9% in Guiyang, and 32.0% in Kunming—highlighting the critical role of secondary aerosol formation. The ratio of NO₃⁻/SO₄²⁻ and nitrogen oxidation ratio to sulfur oxidation ratio (NOR/SOR) indicate a significant transformation of NO₂ under conditions of heavy pollution, with nitrate formation playing an increasingly central role in the haze dynamics, particularly in Chengdu and Chongqing. Utilizing PMF for source apportionment, in Chengdu, vehicle emissions were the predominant contributor, accounting for 33.1%. Chongqing showed a similar profile, with secondary aerosols constituting 36%, followed closely by vehicle emissions. In contrast, Guiyang’s PM_2.5 burden was heavily influenced by coal combustion, which contributed 46.3%, reflecting the city’s strong industrial base. Kunming presented a more balanced source distribution. Back trajectory analysis further confirmed the regional transport of pollutants, illustrating the complex interplay between local and distant sources. These insights underscore the need for tailored, region-specific air quality management strategies in southwestern China, thereby enhancing our understanding of the multifaceted sources and dynamics of PM_2.5 pollution amidst ongoing urban and industrial development. Full article

Karst areas are characterized by poor surface water storage capacity, which makes them more sensitive to drought events. To enhance drought resistance in karst landform areas, this study focuses on a typical region in the Yun–Gui Plateau of China, specifically Guizhou Province, which includes 88 counties and districts. According to the regional characteristics, the index system for the assessment of drought resistance and disaster reduction ability was constructed to include 17 indexes in five evaluation layers, including natural conditions, water conservancy project, economic strength, water usage and water conservation level, and emergency support capacity. A comprehensive evaluation was conducted using a fuzzy evaluation model. Furthermore, the drought resistance and disaster reduction capacity of Guizhou Province was evaluated according to the fulfillment of water supply and water demand under the frequency of 75%, 90%, 95%, 97%, and 99% drought frequency inflow in each research unit. This assessment serves to define the spatial distribution pattern of drought resistance and disaster reduction capability within the province. Additionally, according to the results of the supply–demand balance method, the weight of the main influencing factors in regards to drought resistance and disaster reduction ability was optimized and adjusted to identify the key restricting factors of drought resistance and disaster reduction ability. This research data was obtained from the National Disaster Survey database, aiming to provide practical guidance for drought resistance in Guizhou Province. The research findings show that: (1) the distribution characteristics of drought resistance and disaster reduction capability in Guizhou Province are the most significant in Guiyang City, Liupanshui City, and Anshun City in the southwest, with higher drought resistance and disaster reduction ability found in central region, and lower drought resistance primarily identified in the eastern part of Qiandongnan Prefecture, Tongren City, the southern part of Qiannan Prefecture, and the northwestern part of Bijie City; (2) there are six main influencing factors in the three criterion layers, i.e., hydraulic engineering, emergency drought resistance, and social economy, and their contribution rates are as follows: surface water supply and storage rate > average number of soil moisture monitoring stations > per capita GDP > agricultural emergency drought irrigation rate > regional water supply assurance rate > cultivated land effective irrigation rate. Full article

Globalization and urbanization have reshaped the way that service ecosystem subjects interact with each other in rural communities, providing conditions and possibilities for realizing value co-creation in rural communities. Therefore, this study selected rural communities in Guiyang City, China, as research subjects and explored the value co-creation mechanism in rural communities from the perspective of service ecosystems. The authors construct a theoretical framework encompassing “value co-creation conditions, value co-creation processes, and value co-creation results”. The study found that the core mechanism in the process of value co-creation is “subject embedding, relationship interaction, and resource integration”. At the macro level, resource sharing is achieved through complex and heterogeneous interactions among multiple subjects, under the influence of institutions, policies, and cultures. At the meso level, organizations complement each other’s resources through the cooperation and empowerment of other actors horizontally, under the influence of structure, function, and rules. At the micro level, individuals optimize resources through cooperative and empowering interactions, under the influence of motivations and value preferences. Finally, the integration of individual, organizational, and overall values constitutes public values, under the joint cross-level action of institutional and cultural elements. This study provides a new theoretical perspective for exploring the value co-creation mechanism in rural communities and provides important practical insights for promoting the sustainable development of rural communities. Full article

The optimization design of buildings is very important to the energy consumption, carbon emissions, and sustainable development of buildings. The low-temperature granary has a low grain storage temperature and high energy consumption indexes. The design scheme of the roof insulation for a low-temperature granary should be determined in actual building design processes by considering the costs, carbon emissions, and outdoor climate, comprehensively. In this paper, a new low-carbon optimization design method is proposed for the roof insulation in the low-temperature granary. The low-carbon optimization design method can respond to the cost issue, emission reduction issue, and outdoor climate issue, simultaneously. Moreover, the low-temperature granary roof insulation of different ecological grain storage zones in China is optimized in terms of carbon reduction by using the proposed low-carbon optimization design method. The application results of the optimization design method in different ecological grain storage zones in China indicate that the outdoor climate has significant impacts on the economic performance and carbon reduction effect of roof insulation. The cost considerations related to carbon emissions can apparently increase the economic efficiency of roof insulation. The optimal economic thicknesses of expanded polystyrene (EPS) in the cities of Urumqi, Harbin, Zhengzhou, Changsha, Guiyang, and Haikou are 0.025 m, 0.037 m, 0.085 m, 0.097 m, 0.072 m, and 0.148 m, respectively. The different outdoor climates of the seven ecological grain storage areas in China have important influences on the comprehensive economic performances of low-temperature granary roof insulation. The design of the low-temperature granary roof insulation in Haikou city has the best economic performance among the seven ecological grain storage zones in China. Full article

As an innovative and efficient approach, green finance unlocks the potential to achieve China’s carbon peak and neutrality goals. This study takes China’s Green Finance Pilot Scheme as a quasi-natural experience and adopts the synthetic control method to evaluate the carbon intensity reduction effects of the Green Finance Pilot Policy (GFPP) based on the city-level panel data in China from 2008 to 2019. We find that the GFPP significantly reduces the carbon intensity of pilot cities in eastern China, such as Guangzhou, Huzhou, and Quzhou. However, implementing GFPP does not achieve the desired reduction effect in Nanchang and Guiyang situated in central and western China. After multiple robustness tests, it can be proved that the preceding conclusions are robust. The mechanism analysis results show that the GFPP can promote carbon intensity reduction through financial agglomeration and green innovation. This study is conducive to assessing the policy effectiveness of China’s GFPP and provides empirical evidence for promoting green finance system construction in China. Full article

Due to the accompaniment of vascular endothelial inflammation during the occurrence and development of cardiovascular diseases (CVD), treatment modalities against vascular endothelial inflammation have been intensively investigated for CVD prevention and/or treatment. Vascular cell adhesion molecule-1 (VCAM-1) is a typical transmembrane inflammatory protein specifically expressed by inflammatory vascular endothelial. By inhibiting VCAM-1 expression through the miR-126 mediated pathway, vascular endothelial inflammation can be efficiently relieved. Inspired by this, we developed a miR-126-loaded immunoliposome with VCAM-1 monoclonal antibody (VCAM_ab) decorated at its surface. This immunoliposome can be directly targeted to VCAM-1 at the inflammatory vascular endothelial membrane surface and achieve highly efficient treatment against inflammation response. The cellular experiment results showed the immunoliposome had a higher uptake rate towards inflammatory human vein endothelial cells (HUVECs) and can significantly downregulate the VCAM-1 expression level of inflammatory HUVECs. In vivo investigation further demonstrated that this immunoliposome displayed a higher accumulation rate at vascular inflammatory dysfunction sites than its non-VCAM_ab-modified counterpart. These results suggest that this novel nanoplatform can effectively deliver miR-126 to vascular inflammatory endothelium, opening a new avenue for the safe and effective delivery of miRNA for potential clinical application. Full article