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  • Review
  • Open Access
5 Citations
2,943 Views
17 Pages

Contrast-Enhanced Harmonic Endoscopic Ultrasonography for Prediction of Aggressiveness and Treatment Response in Patients with Pancreatic Lesions

  • Marco Spadaccini,
  • Gianluca Franchellucci,
  • Marta Andreozzi,
  • Maria Terrin and ,
  • Matteo Tacelli,
  • Piera Zaccari,
  • Maria Chiara Petrone,
  • Gaetano Lauri,
  • Matteo Colombo and
  • Silvia Carrara
  • + 14 authors+ 9 authors

1 August 2025

Endoscopic ultrasonography represents a crucial aspect of the diagnosis of pancreatic lesions. The echo-endoscopic features of pancreatic lesions, particularly their contrast behavior with the advent of Contrast-Enhanced EUS (CE-EUS) and Contrast Enh...

(This article belongs to the Section Methods and Technologies Development)
  • Article
  • Open Access
8 Citations
3,053 Views
14 Pages

Early Childhood Growth Parameters in South African Children with Exposure to Maternal HIV Infection and Placental Insufficiency

  • Mothusi Nyofane,
  • Marinel Hoffman,
  • Helen Mulol,
  • Tanita Botha and ,
  • Valerie Vannevel,
  • Robert Pattinson and
  • Ute Feucht
  • + 2 authors+ 0 author

9 December 2022

Maternal HIV exposure and intrauterine growth restriction (IUGR) due to placental insufficiency both carry major risks to early child growth. We compared the growth outcomes of children aged 18 months who had abnormal umbilical artery resistance indi...

(This article belongs to the Special Issue Pediatric HIV Infection and AIDS)
  • Review
  • Open Access
22 Citations
4,217 Views
14 Pages

Immune and Metabolic Alterations in Children with Perinatal HIV Exposure

  • Louise D. V. du Toit,
  • Andrea Prinsloo,
  • Helen C. Steel,
  • Ute Feucht and ,
  • Roan Louw and
  • Theresa M. Rossouw
  • + 1 author+ 0 author

18 January 2023

With the global rollout of mother-to-child prevention programs for women living with HIV, vertical transmission has been all but eliminated in many countries. However, the number of children who are exposed in utero to HIV and antiretroviral therapy...

(This article belongs to the Special Issue Pediatric HIV Infection and AIDS)
  • Article
  • Open Access
12 Citations
3,526 Views
11 Pages

Clinical Utility of the Contrast-Enhanced Endoscopic Ultrasound Guided Fine Needle Aspiration in the Diagnosis of Pancreatic Cyst

  • Miruna Patricia Olar,
  • Sorana D. Bolboacă,
  • Cristina Pojoga,
  • Ofelia Moșteanu and ,
  • Marcel Gheorghiu,
  • Radu Seicean,
  • Ioana Rusu,
  • Zeno Sparchez,
  • Nadim Al Hajjar and
  • Andrada Seicean
  • + 5 authors+ 0 author

12 September 2022

Endoscopic ultrasound fine needle aspiration (EUS-FNA) cytology from an intracystic fluid is useful in the differentiation of pancreatic cysts, with low sensitivity, which increases when the solid component is targeted. The clinical utility of contra...

(This article belongs to the Special Issue Advances in Endoscopic Ultrasound)
  • Review
  • Open Access
13 Citations
4,845 Views
14 Pages

30 October 2020

Although endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) is useful in the differential diagnosis of solid pancreatic lesions, lymph nodes, and liver lesions, inadequate sampling may result in an incorrect pathological diagnosis. The acc...

(This article belongs to the Special Issue The Advanced Role of Diagnostic Endoscopic Ultrasonography)
  • Case Report
  • Open Access
8 Citations
2,795 Views
8 Pages

Usefulness of Contrast-Enhanced Endoscopic Ultrasound (CH-EUS) to Guide the Treatment Choice in Superficial Rectal Lesions: A Case Series

  • Giulia Gibiino,
  • Monica Sbrancia,
  • Cecilia Binda,
  • Chiara Coluccio and ,
  • Stefano Fabbri,
  • Paolo Giuffrida,
  • Graziana Gallo,
  • Luca Saragoni,
  • Roberta Maselli and
  • Carlo Fabbri
  • + 6 authors+ 1 author

Introduction: Large rectal lesions can conceal submucosal invasion and cancer nodules. Despite the increasing diffusion of high-definition endoscopes and the importance of an accurate morphological evaluation, a complete assessment in this setting ca...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Article
  • Open Access
3 Citations
2,468 Views
10 Pages

Diagnostic Dilemma of Biliopancreatic Contrast-Enhanced Harmonic Endoscopic Ultrasonography

  • Keisuke Kanazawa,
  • Masafumi Chiba,
  • Masayuki Kato,
  • Yuji Kinoshita and ,
  • Takafumi Akasu,
  • Hiroaki Matsui,
  • Nana Shimamoto,
  • Youichi Tomita,
  • Takahiro Abe and
  • Kazuki Sumiyama
  • + 9 authors+ 4 authors

Background: The utility of contrast-enhanced harmonic endoscopic ultrasonography (CH-EUS) alone in the biliopancreatic region appears to be limited because it is highly dependent on the experience and skill of the endoscopist. Therefore, the present...

(This article belongs to the Special Issue Endoscopy and Diagnostic Tools in Hepatobiliary and Pancreatic Diseases)
  • Article
  • Open Access
4 Citations
2,904 Views
12 Pages

Should Contrast-Enhanced Harmonic Endoscopic Ultrasound Be Incorporated into the International Consensus Guidelines to Determine the Appropriate Treatment of Intraductal Papillary Mucinous Neoplasm?

  • Tomohiro Yamazaki,
  • Mamoru Takenaka,
  • Shunsuke Omoto,
  • Tomoe Yoshikawa and ,
  • Rei Ishikawa,
  • Ayana Okamoto,
  • Atsushi Nakai,
  • Kosuke Minaga,
  • Ken Kamata and
  • Masatoshi Kudo
  • + 14 authors+ 9 authors

22 April 2021

This study aimed to investigate whether the incorporation of contrast-enhanced harmonic endoscopic ultrasound (CH-EUS) into the international consensus guidelines (ICG) for the management of intraductal papillary mucinous neoplasm (IPMN) could improv...

(This article belongs to the Special Issue Clinical Advances of Endoscopy in Pancreaticobiliary Disease)
  • Review
  • Open Access
13 Citations
3,534 Views
10 Pages

The Role of Contrast-Enhanced Harmonic Endoscopic Ultrasound in Interventional Endoscopic Ultrasound

  • Cecilia Binda,
  • Chiara Coluccio,
  • Gianmarco Marocchi,
  • Monica Sbrancia and
  • Carlo Fabbri

11 October 2021

Over the last decades, contrast-enhanced harmonic endoscopic ultrasound (CH-EUS) has emerged as an important diagnostic tool for the diagnosis and differentiation of several gastrointestinal diseases. The key advantage of CH-EUS is that the influx an...

(This article belongs to the Special Issue Recent Advances in Biliopancreatic Endoscopy)
  • Article
  • Open Access
15 Citations
2,983 Views
13 Pages

Usefulness of Contrast-Enhanced Harmonic Endoscopic Ultrasonography for Diagnosis of Malignancy in Intraductal Papillary Mucinous Neoplasm

  • Yasunobu Yamashita,
  • Yuki Kawaji,
  • Toshio Shimokawa,
  • Hirofumi Yamazaki and ,
  • Takashi Tamura,
  • Keiichi Hatamaru,
  • Masahiro Itonaga,
  • Reiko Ashida,
  • Manabu Kawai and
  • Masayuki Kitano
  • + 5 authors+ 0 author

2 September 2022

Intraductal papillary mucinous neoplasms (IPMNs) have a wide pathologic spectrum and it can be difficult to diagnose malignancy, including pathological grade. The aim of this study was to evaluate contrast-enhanced harmonic endoscopic ultrasonography...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Article
  • Open Access
26 Citations
5,538 Views
9 Pages

Utility of Contrast-Enhanced Harmonic Endoscopic Ultrasonography for Early Diagnosis of Small Pancreatic Cancer

  • Yasunobu Yamashita,
  • Kensuke Tanioka,
  • Yuki Kawaji,
  • Takashi Tamura and ,
  • Junya Nuta,
  • Keiichi Hatamaru,
  • Masahiro Itonaga,
  • Takeichi Yoshida,
  • Yoshiyuki Ida and
  • Masayuki Kitano
  • + 13 authors+ 8 authors

This study aimed to assess whether contrast-enhanced harmonic endoscopic ultrasonography (CH-EUS), compared to multidetector-row computed tomography (MDCT) and magnetic resonance imaging (MRI), is useful for early diagnosis of small pancreatic cancer...

(This article belongs to the Special Issue Endoscopic Diagnostics for Pancreatobiliary Disorders)
  • Article
  • Open Access
6 Citations
2,362 Views
14 Pages

Contrast-Enhanced Harmonic Endoscopic Ultrasound for Diagnosis of the Aggressiveness of Pancreatic Neuroendocrine Neoplasm

  • Takashi Tamura,
  • Yuto Sugihara,
  • Hirofumi Yamazaki,
  • Hiromu Koutani and ,
  • Takaaki Tamura,
  • Ikuhisa Tsuda,
  • Tomoya Emori,
  • Yuki Kawaji,
  • Keiichi Hatamaru and
  • Masayuki Kitano
  • + 8 authors+ 3 authors

29 November 2022

The purpose of this study is to clarify the associations between the enhancement patterns on contrast-enhanced harmonic endoscopic ultrasound (CH-EUS) and the aggressiveness and prognosis of pancreatic neuroendocrine neoplasms (PanNENs). Patients who...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Article
  • Open Access
2 Citations
1,198 Views
12 Pages

Contrast-Enhanced Harmonic Endoscopic Ultrasonography for Diagnosing Gastric Subepithelial Tumors

  • Moon Won Lee,
  • Dong Chan Joo,
  • Gwang Ha Kim,
  • Bong Eun Lee and
  • Hye Kyung Jeon

Background/Objectives: Contrast-enhanced harmonic endoscopic ultrasonography (CH-EUS) is a promising tool for differentiating gastric subepithelial tumors (SETs). However, most published studies have mainly included gastrointestinal stromal tumors (G...

(This article belongs to the Special Issue New Advances in Gastrointestinal Endoscopy)
  • Article
  • Open Access
7 Citations
2,510 Views
13 Pages

Health Outcomes at School Age among Children Who Are HIV-Exposed but Uninfected with Detected Mitochondrial DNA Depletion at One Year

  • Audrey Monnin,
  • Nicolas Nagot,
  • Sabrina Eymard-Duvernay,
  • Nicolas Meda and ,
  • James K. Tumwine,
  • Thorkild Tylleskär,
  • Philippe Van de Perre and
  • Jean-Pierre Molès
  • + 3 authors+ 0 author

16 November 2020

Infant antiretroviral (ARV) prophylaxis given to children who are human immunodeficiency virus (HIV)-exposed but uninfected (CHEU) to prevent HIV transmission through breastfeeding previously proved its efficacy in the fight against the pediatric epi...

(This article belongs to the Section Infectious Diseases)
  • Review
  • Open Access
9 Citations
3,794 Views
10 Pages

Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) is useful for the diagnosis of pancreatic masses. According to three meta-analyses, the sensitivity, specificity, and accuracy of EUS-FNA are 84–92%, 96–98%, and 86–91%,...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Review
  • Open Access
7 Citations
4,330 Views
11 Pages

Role of Endoscopy in Esophageal Tuberculosis: A Narrative Review

  • Tong Ye,
  • Ye Zong,
  • Guiping Zhao,
  • Anni Zhou and ,
  • Bing Yue,
  • Haiying Zhao and
  • Peng Li
  • + 2 authors+ 0 author

27 November 2022

Esophageal tuberculosis (ET) is a rare infectious disease of the gastrointestinal tract. Awareness of ET is deficient due to its low incidence. Unexplained dysphagia and upper gastrointestinal bleeding are the most common symptoms of ET. The prognosi...

(This article belongs to the Special Issue Endoscopic Ultrasound-Guided Diagnosis and Treatment of Gastrointestinal Diseases)
  • Article
  • Open Access
5 Citations
2,778 Views
15 Pages

Longitudinal Follow-Up of Blood Telomere Length in HIV-Exposed Uninfected Children Having Received One Year of Lopinavir/Ritonavir or Lamivudine as Prophylaxis

  • Audrey Monnin,
  • Amélie Vizeneux,
  • Nicolas Nagot,
  • Sabrina Eymard-Duvernay and ,
  • Nicolas Meda,
  • Mandisa Singata-Madliki,
  • Grace Ndeezi,
  • James Kashugyera Tumwine,
  • Chipepo Kankasa and
  • Jean-Pierre Molès
  • + 8 authors+ 3 authors

10 September 2021

Telomere shortening can be enhanced upon human immunodeficiency virus (HIV) infection and by antiretroviral (ARV) exposures. The aim of this study was to evaluate the acute and long-term effect on telomere shortening of two ARV prophylaxes, lopinavir...

(This article belongs to the Section Pediatric Infectious Diseases)
  • Review
  • Open Access
8 Citations
4,006 Views
30 Pages

Comments on and Illustrations of the EFSUMB CEUS Guidelines: Transabdominal and Endoscopic Ultrasound Features of Intrapancreatic Metastases and the Role of Multiparametric Imaging and EUS-Guided Sampling in Rare Pancreatic Tumors

  • Kathleen Möller,
  • Christian Jenssen,
  • Barbara Braden,
  • Michael Hocke and ,
  • Yasunobu Yamashita,
  • Paolo Giorgio Arcidiacono,
  • André Ignee,
  • Mirko D’Onofrio,
  • Pietro Fusaroli and
  • Christoph F. Dietrich
  • + 9 authors+ 4 authors

29 April 2023

A definite pathologic diagnosis of intrapancreatic metastasis is crucial for the management decision, i.e., curative or palliative surgery versus chemotherapy or conservative/palliative therapy. This review focuses on the appearance of intrapancreati...

  • Review
  • Open Access
16 Citations
4,420 Views
14 Pages

Contrast Enhanced EUS for Predicting Solid Pancreatic Neuroendocrine Tumor Grade and Aggressiveness

  • Gianluca Franchellucci,
  • Marta Andreozzi,
  • Silvia Carrara,
  • Luca De Luca and ,
  • Francesco Auriemma,
  • Danilo Paduano,
  • Federica Calabrese,
  • Antonio Facciorusso,
  • Valeria Poletti and
  • Benedetto Mangiavillano
  • + 15 authors+ 10 authors

Pancreatic neuroendocrine tumor (PNET) behavior assessment is a daily challenge for physicians. Modern PNET management varies from a watch-and-wait strategy to surgery depending on tumor aggressiveness. Therefore, the aggressiveness definition plays...

(This article belongs to the Special Issue Endoscopy and Diagnostic Tools in Hepatobiliary and Pancreatic Diseases)
  • Systematic Review
  • Open Access
14 Citations
4,298 Views
15 Pages

Biliopancreatic Endoscopy in Altered Anatomy

  • Ilaria Tarantino and
  • Giacomo Emanuele Maria Rizzo

25 September 2021

Background and Objectives: Anatomical post-surgical alterations of the upper gastrointestinal (GI) tract have always been challenging for performing diagnostic and therapeutic endoscopy, especially when biliopancreatic diseases are involved. Esophage...

(This article belongs to the Special Issue Recent Advances in Biliopancreatic Endoscopy)
  • Article
  • Open Access
11 Citations
3,378 Views
10 Pages

Comparison of 22G Fork-Tip and Franseen Needles and Usefulness of Contrast-Enhanced Endoscopic Ultrasound for Diagnosis of Upper Gastrointestinal Subepithelial Lesions

  • Yasunobu Yamashita,
  • Reiko Ashida,
  • Hirofumi Yamazaki,
  • Yuki Kawaji and ,
  • Toshio Shimokawa,
  • Takashi Tamura,
  • Keiichi Hatamaru,
  • Masahiro Itonaga and
  • Masayuki Kitano
  • + 4 authors+ 0 author

11 December 2022

Endoscopic ultrasound (EUS)-guided tissue acquisition (EUS-TA) is less accurate in obtaining samples from gastrointestinal subepithelial lesions (SELs) ≤2 cm than from pancreatic cancers. The present study compared the usefulness of 22G Fork-tip a...

(This article belongs to the Special Issue Endoscopic Ultrasound-Guided Fine-Needle Aspiration (EUS-FNA))
  • Article
  • Open Access
6 Citations
3,589 Views
19 Pages

Mitochondrial DNA Parameters in Blood of Infants Receiving Lopinavir/Ritonavir or Lamivudine Prophylaxis to Prevent Breastfeeding Transmission of HIV-1

  • Audrey Monnin,
  • Nicolas Nagot,
  • Marianne Periès,
  • Roselyne Vallo and ,
  • Nicolas Meda,
  • Mandisa Singata-Madliki,
  • James K. Tumwine,
  • Chipepo Kankasa,
  • Nobubelo Ngandu and
  • Jean-Pierre Molès
  • + 9 authors+ 4 authors

14 September 2020

Children who are human immunodeficiency virus (HIV)-exposed but uninfected (CHEU) accumulate maternal HIV and antiretroviral exposures through pregnancy, postnatal prophylaxis, and breastfeeding. Here, we compared the dynamics of mitochondrial DNA (m...

(This article belongs to the Section Infectious Diseases)
  • Article
  • Open Access
5 Citations
3,829 Views
15 Pages

Ca2+-Dependent Protein Kinase 6 Enhances KAT2 Shaker Channel Activity in Arabidopsis thaliana

  • Elsa Ronzier,
  • Claire Corratgé-Faillie,
  • Frédéric Sanchez,
  • Christian Brière and
  • Tou Cheu Xiong

5 February 2021

Post-translational regulations of Shaker-like voltage-gated K+ channels were reported to be essential for rapid responses to environmental stresses in plants. In particular, it has been shown that calcium-dependent protein kinases (CPKs) regulate Sha...

(This article belongs to the Special Issue Ion Channel and Ion-Related Signaling 2020)
  • Review
  • Open Access
194 Citations
76,379 Views
22 Pages

Palm Oil Mill Effluent Treatment Processes—A Review

  • Sharifah Mohammad,
  • Siti Baidurah,
  • Takaomi Kobayashi,
  • Norli Ismail and
  • Cheu Peng Leh

22 April 2021

Ponding system or land application techniques are widely used at industrial scale to treat palm oil mill effluent (POME) prior to discharge to the environment. POME is considered as one of the major problems that has generated voluminously from the p...

  • Article
  • Open Access
3 Citations
3,847 Views
19 Pages

Selection and Implementation of Intelligent Transportation Systems for Work Zone Construction Projects

  • Mehdi Azimi,
  • Ibukunoluwa Oyelade,
  • Akintola Moses Aremu,
  • Esmaeil Balal and ,
  • Ruey Long Cheu and
  • Yi Qi
  • + 1 author+ 0 author

The extent of the deployment of Intelligent Transportation Systems (ITSs) for work zone construction projects has increased in recent years. However, highway agencies are unable to meet the full demand of the deployment of ITSs in work zones in a fis...

  • Feature Paper
  • Article
  • Open Access
6 Citations
5,801 Views
20 Pages

Characterization of Flavoured Olive Oils of ‘Madural’ Variety

  • María Helena Chéu-Guedes,
  • M. Dolores La Rubia,
  • Sebastián Sánchez,
  • Natividad Ramos and
  • Rafael Pacheco

9 January 2023

Flavoured oils arouse great interest among consumers in many countries due to their variety of flavours and versatility, especially in the culinary field. The aromatization of oils seeks to improve their sensory and nutritional properties, and extend...

(This article belongs to the Special Issue Innovations and New Processes in the Olive Oil Industry)
  • Article
  • Open Access
10 Citations
3,613 Views
14 Pages

Quinazolinone-Peptido-Nitrophenyl-Derivatives as Potential Inhibitors of SARS-CoV-2 Main Protease

  • Huynh-Nguyet-Huong Giang,
  • Feng-Pai Chou,
  • Ching-Yun Chen,
  • Shen-Chieh Chou and ,
  • Sheng-Cih Huang,
  • Tuoh Wu,
  • Bui-Thi-Buu Hue,
  • Hong-Cheu Lin and
  • Tung-Kung Wu
  • + 4 authors+ 0 author

19 January 2023

The severe acute respiratory syndrome coronavirus 2 main protease (SARS-CoV-2-Mpro) plays an essential role in viral replication, transcription, maturation, and entry into host cells. Furthermore, its cleavage specificity for viruses, but not humans,...

(This article belongs to the Section Viral Immunology, Vaccines, and Antivirals)
  • Communication
  • Open Access
15 Citations
3,452 Views
8 Pages

Updated Mineral Composition and Potential Therapeutic Properties of Different Varieties of Olive Leaves from Olea europaea

  • Natália M. de Oliveira,
  • Lara Lopes,
  • Maria Helena Chéu,
  • Eugénio Soares and ,
  • Diana Meireles and
  • Jorge Machado
  • + 1 author+ 0 author

17 February 2023

Olea europaea L. folium has been studied for its potential nutraceutical properties. Quantitative and qualitative analyses were conducted on samples of Madural, Verdeal, and Cobrançosa elementary leaves and leave sprouts (mamões) collec...

(This article belongs to the Special Issue Identification and Analysis of Bioactive Components from Plants)
  • Article
  • Open Access
27 Citations
6,401 Views
19 Pages

Updated Organic Composition and Potential Therapeutic Properties of Different Varieties of Olive Leaves from Olea europaea

  • Diana Melo Ferreira,
  • Natália M. de Oliveira,
  • Maria Helena Chéu,
  • Diana Meireles and ,
  • Lara Lopes,
  • Maria Beatriz Oliveira and
  • Jorge Machado
  • + 2 authors+ 0 author

3 February 2023

Olea europaea L. folium merits further exploration of the potential of its substrates for therapeutic supplements. Quantitative and qualitative analyses were conducted on samples of Madural, Verdeal, and Cobrançosa elementary leaves and leaf s...

(This article belongs to the Special Issue Identification and Analysis of Bioactive Components from Plants)
  • Article
  • Open Access
2 Citations
3,945 Views
15 Pages

Plant Viruses Can Alter Aphid-Triggered Calcium Elevations in Infected Leaves

  • Christiane Then,
  • Fanny Bellegarde,
  • Geoffrey Schivre,
  • Alexandre Martinière and ,
  • Jean-Luc Macia,
  • Tou Cheu Xiong and
  • Martin Drucker
  • + 2 authors+ 0 author

14 December 2021

Alighting aphids probe a new host plant by intracellular test punctures for suitability. These induce immediate calcium signals that emanate from the punctured sites and might be the first step in plant recognition of aphid feeding and the subsequent...

(This article belongs to the Section Plant, Algae and Fungi Cell Biology)
  • Article
  • Open Access
14 Citations
5,631 Views
31 Pages

Potential Therapeutic Properties of Olea europaea Leaves from Selected Cultivars Based on Their Mineral and Organic Profiles

  • Natália M. de Oliveira,
  • Jorge Machado,
  • Maria Helena Chéu,
  • Lara Lopes and ,
  • M. Fátima Barroso,
  • Aurora Silva,
  • Sara Sousa,
  • Valentina F. Domingues and
  • Clara Grosso
  • + 4 authors+ 0 author

22 February 2024

Olive leaves are consumed as an extract or as a whole herbal powder with several potential therapeutic benefits attributed to polyphenols, tocopherol’s isomers, and flavonoids, among others. This study assessed the potential variance in the fun...

(This article belongs to the Special Issue Neuroprotective Potential of Natural Products: A Shield against Brain Decay)
  • Review
  • Open Access
34 Citations
31,356 Views
34 Pages

Therapeutic Potential of Olive Leaf Extracts: A Comprehensive Review

  • Natália M. de Oliveira,
  • Jorge Machado,
  • Maria Helena Chéu,
  • Lara Lopes and
  • Maria Begoña Criado

22 September 2024

The olive tree is currently cultivated worldwide, with higher incidence in Mediterranean Basin. Its climate is highly favorable to the synthesis of phenolic compounds, stored in olive leaves; their consumption has been linked to a lower incidence of...

(This article belongs to the Special Issue Plant Natural Compounds: From Discovery to Application)
  • Article
  • Open Access
13 Citations
3,221 Views
10 Pages

This study applied ARIMA modeling to analyze the energy consumption patterns of laboratory equipment over one month, focusing on enhancing energy management in the laboratory. By explicitly examining AC and DC equipment, this study obtained detailed...

  • Article
  • Open Access
7,910 Views
18 Pages

Synergistic Effect of Human Papillomavirus and Environmental Factors on Skin Squamous Cell Carcinoma, Basal Cell Carcinoma, and Melanoma: Insights from a Taiwanese Cohort

  • Chun-Chia Chen,
  • Ci-Wen Luo,
  • Stella Chin-Shaw Tsai,
  • Jing-Yang Huang and ,
  • Shun-Fa Yang and
  • Frank Cheu-Feng Lin
  • + 1 author+ 0 author

20 June 2024

Human papillomavirus (HPV) has been implicated in various cancers, including those affecting the skin. The study assessed the long-term risk of skin cancer associated with HPV infection in Taiwan region, using data from the National Health Insurance...

(This article belongs to the Special Issue Viruses in Cancer Etiology)
  • Article
  • Open Access
10 Citations
7,325 Views
24 Pages

Nonclinical Pharmacokinetics and Pharmacodynamics Characterization of Anti-CD79b/CD3 T Cell-Dependent Bispecific Antibody Using a Surrogate Molecule: A Potential Therapeutic Agent for B Cell Malignancies

  • Rajbharan Yadav,
  • Siddharth Sukumaran,
  • Tanja S. Zabka,
  • Jinze Li and ,
  • Amy Oldendorp,
  • Gary Morrow,
  • Arthur Reyes,
  • Melissa Cheu,
  • Jessica Li and
  • Meric A. Ovacik
  • + 14 authors+ 9 authors

The T cell-dependent bispecific (TDB) antibody, anti-CD79b/CD3, targets CD79b and CD3 cell-surface receptors expressed on B cells and T cells, respectively. Since the anti-CD79b arm of this TDB binds only to human CD79b, a surrogate TDB that binds to...

(This article belongs to the Section Pharmacokinetics and Pharmacodynamics)
  • Article
  • Open Access
4 Citations
688 Views
29 Pages

A Hybrid Mechanistic–AI Framework for Degradation-Aware Energy Analysis and Maintenance-Oriented Decision Support in Bioethanol Production

  • Yitong Niu,
  • Natra Joseph,
  • Ireland LaBass,
  • Sicheng Wang and ,
  • Chee Keong Lee,
  • Cheu Peng Leh and
  • Ting Han
  • + 2 authors+ 0 author

1 June 2026

Bioethanol production from lignocellulosic biomass remains energy-intensive, and its energy performance can be affected by equipment degradation, utility disturbances, and operating variability. This study developed a degradation-aware mechanistic&nd...

(This article belongs to the Special Issue Energy Efficiency, Renewable Integration, and Systematic Energy Management for Decarbonisation of Industrial and Agricultural Processes)
  • Article
  • Open Access
7 Citations
3,579 Views
16 Pages

Developmental Disorder Probability Scores at 6–18 Years Old in Relation to In-Utero/Peripartum Antiretroviral Drug Exposure among Ugandan Children

  • Jorem Emmillian Awadu,
  • Alla Sikorskii,
  • Sarah Zalwango,
  • Audrey Coventry and ,
  • Bruno Giordani and
  • Amara E. Ezeamama
  • + 1 author+ 0 author

(1) We examined the hypothesis that in utero/peripartum antiretroviral (IPA) exposure may affect the likelihood of developmental disorders—i.e., attention deficit and hyperactivity disorder (ADHD), autism spectrum disorder (ASD), and functional...

(This article belongs to the Special Issue Health Consequences of Prenatal Exposure to Adverse Environmental Factors in Infants and Children)
  • Article
  • Open Access
2 Citations
2,806 Views
16 Pages

Vitamin D and Probability of Developmental Disorders among Perinatally HIV-Affected and Unaffected Ugandan Children

  • Jorem E. Awadu,
  • Bruno Giordani,
  • Alla Sikorskii,
  • Catherine Abbo and ,
  • Jenifer I. Fenton,
  • Sarah Zalwango and
  • Amara Esther Ezeamama
  • + 2 authors+ 0 author

22 April 2023

We tested the hypothesis that vitamin D deficiency (VDD) is associated with higher developmental disorder probability in 604 children with perinatal HIV infection (CPHIV, n = 199), HIV exposed and uninfected (CHEU, n = 196), and HIV unexposed uninfec...

(This article belongs to the Section Nutrition and Public Health)
  • Review
  • Open Access
12 Citations
8,018 Views
17 Pages

Recent Advances in Endoscopic Ultrasound for Gallbladder Disease Diagnosis

  • Kosuke Takahashi,
  • Eisuke Ozawa,
  • Akane Shimakura,
  • Tomotaka Mori and ,
  • Hisamitsu Miyaaki and
  • Kazuhiko Nakao
  • + 1 author+ 0 author

Gallbladder (GB) disease is classified into two broad categories: GB wall-thickening and protuberant lesions, which include various lesions, such as adenomyomatosis, cholecystitis, GB polyps, and GB carcinoma. This review summarizes recent advances i...

(This article belongs to the Section Pathology and Molecular Diagnostics)