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Search Results (263)

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Keywords = ANN-MLP

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19 pages, 11009 KB  
Article
The Application of CA–MLP–ANN in Assessing Urbanisation in Quaternary Catchment X22J of Mpumalanga, South Africa
by Mary Nkosi and Fhumulani I. Mathivha
Land 2025, 14(11), 2099; https://doi.org/10.3390/land14112099 - 22 Oct 2025
Abstract
Quaternary catchment X22J boasts ecological biodiversity, making ecotourism one of the thriving industries in the catchment. However, recent population growth and the migration from rural areas to urban areas have increased urbanisation. Therefore, this study aimed to assess and predict the trajectory of [...] Read more.
Quaternary catchment X22J boasts ecological biodiversity, making ecotourism one of the thriving industries in the catchment. However, recent population growth and the migration from rural areas to urban areas have increased urbanisation. Therefore, this study aimed to assess and predict the trajectory of urban growth. Through the random forest algorithm in Google Earth Engine, this study analysed urban use in 1990, 2007 and 2024. The classification achieved an overall score of 0.89, 0.96 and 0.91 for 1990, 2007 and 2024, respectively. In addition, the Kappa coefficient varied between 0.85, 0.83 and 0.87 for 1990, 2007 and 2024. The CA–MLP–ANN algorithm was applied for the prediction of 2040 urban changes, leading to the model achieving a score of an overall Kappa coefficient of 0.52 and 74% correctness. Overall, the study predicted an increase of 4.01% in built-up areas from 2024 to 2040, maintaining the increasing trend from 1990. Consequently, a loss of 11% was observed in agricultural lands and a loss of 0.17 in waterbodies by 2040. Full article
(This article belongs to the Special Issue Land Use and Land Cover Change Analysis in Dynamic Landscapes)
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11 pages, 3762 KB  
Proceeding Paper
Multi-Layer Perceptron Neural Networks for Concrete Strength Prediction: Balancing Performance and Optimizing Mix Designs
by Younes Alouan, Seif-Eddine Cherif, Badreddine Kchakech, Youssef Cherradi and Azzouz Kchikach
Eng. Proc. 2025, 112(1), 1; https://doi.org/10.3390/engproc2025112001 - 14 Oct 2025
Viewed by 216
Abstract
Optimizing concrete production requires balancing ingredient ratios and using local resources to produce an economical material with the desired consistency, strength, and durability. Compressive strength is crucial for structural design, yet predicting it accurately is challenging due to the complex interplay of various [...] Read more.
Optimizing concrete production requires balancing ingredient ratios and using local resources to produce an economical material with the desired consistency, strength, and durability. Compressive strength is crucial for structural design, yet predicting it accurately is challenging due to the complex interplay of various factors, including component types, water–cement ratio, and curing time. This study employs a Multi-layer Perceptron Neural Network (ANN_MLP) to model the relationship between input variables and the compressive strength of normal and high-performance concrete. A dataset of 1030 samples from the literature was used for training and evaluation. The optimized ANN_MLP configuration included 16 neurons in a single hidden layer, with the ‘tanh’ activation function and ‘sgd’ solver. It achieved an R2 of 0.892, an MAE of 3.648 MPa, and an RMSE of 5.13 MPa. The model was optimized using a univariate sensitivity analysis to measure the impact of each hyperparameter on performance and select optimal values to maximize the accuracy and robustness. Full article
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18 pages, 2853 KB  
Article
Artificial Neural Network Models for the Prediction of Ammonia Concentrations in a Mediterranean Dairy Barn
by Luciano Manuel Santoro, Provvidenza Rita D’Urso, Claudia Arcidiacono, Fabio Massimo Frattale Mascioli and Salvatore Coco
Animals 2025, 15(20), 2967; https://doi.org/10.3390/ani15202967 - 14 Oct 2025
Viewed by 287
Abstract
Understanding the relationship between environmental variables and gas concentrations from livestock production is essential for evaluating the impact of pollutants on animal housing and surrounding areas. This study investigates the use of ANNs to predict NH3 concentrations in a Mediterranean dairy barn [...] Read more.
Understanding the relationship between environmental variables and gas concentrations from livestock production is essential for evaluating the impact of pollutants on animal housing and surrounding areas. This study investigates the use of ANNs to predict NH3 concentrations in a Mediterranean dairy barn under seasonal conditions—namely, hot, cold, and transitional weather. A Multi-Layer Perceptron (MLP) structure was employed, trained using Levenberg–Marquardt and Bayesian Regularization algorithms. The input dataset included ten variables related to internal and external environmental conditions, NH3 concentrations, and time of day. The models were evaluated using R2, R, MAE, MSE, and RMSE as performance metrics. Results showed strong predictive capabilities, with R2 values ranging from 0.75 to 0.96 and RMSE values between 0.47 and 0.80 due to the number of input data (different days) and environmental conditions. These findings highlight the potential of ANNs as effective tools for real-time pollutant prediction, supporting Precision Livestock Farming (PLF) strategies. Full article
(This article belongs to the Special Issue Sustainable Strategies for Intensive Livestock Production Systems)
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19 pages, 6709 KB  
Article
Experimental and Dynamic Modeling of a Variable-Pitch VAWT Using a Neural Network and the DMST Model
by Luz M. Sanchez-Rivera, Jorge Díaz-Salgado, Oliver M. Huerta-Chávez and Jesús García-Barrera
Appl. Sci. 2025, 15(20), 10989; https://doi.org/10.3390/app152010989 - 13 Oct 2025
Viewed by 204
Abstract
The mathematical modeling and experimental validation of a non-conventional vertical-axis wind turbine (VAWT) with a variable-pitch angle are presented, employing the Double-Multiple Streamtube (DMST) method to simulate aerodynamic performance. The aerodynamic coefficients required by the model are obtained through a data-driven approach using [...] Read more.
The mathematical modeling and experimental validation of a non-conventional vertical-axis wind turbine (VAWT) with a variable-pitch angle are presented, employing the Double-Multiple Streamtube (DMST) method to simulate aerodynamic performance. The aerodynamic coefficients required by the model are obtained through a data-driven approach using a multi-input, two-output multilayer perceptron artificial neural network (MLP–ANN). The model is validated through numerical simulations under two distinct wind input profiles. An experimental evaluation with a prototype replicates the step input. It shows strong agreement with the simulations, particularly in the angular velocity response, which fluctuates between 35 and 55 RPM, with an average value in the range of 40–45 RPM. This hybrid methodology enhances the modeling fidelity of VAWTs and provides a scalable framework for real-time aerodynamic analysis and control. Full article
(This article belongs to the Special Issue Advanced Wind Turbine Control and Optimization)
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32 pages, 5321 KB  
Article
Optimization of Artificial Neural Networks for Predicting the Radiological Risks of Thermal Waters in Türkiye
by Selin Erzin
Appl. Sci. 2025, 15(20), 10891; https://doi.org/10.3390/app152010891 - 10 Oct 2025
Viewed by 170
Abstract
In this study, the prediction of four radiological risk parameters of thermal waters in Türkiye (dose contribution (DE) from radon release in thermal water to air for workers and visitors, the annual effective dose from radon ingestion (Ding [...] Read more.
In this study, the prediction of four radiological risk parameters of thermal waters in Türkiye (dose contribution (DE) from radon release in thermal water to air for workers and visitors, the annual effective dose from radon ingestion (Ding) and the annual effective dose to the stomach from radon ingestion (Dsto)) from three physicochemical properties of thermal waters (electrical conductivity (EC), pH and temperature (T)) was investigated using multilayer perceptron (MLP) and radial basis function (RBF) artificial neural networks (ANNs). To achieve this, two separate MLPANN and RBFANN models were constructed using data from the literature. The MLPANN and RBFANN models were verified using performance metrics (relative absolute error (RAE), root mean square error (RMSE), mean absolute error (MAE), and ratio of RMSE to data standard deviation (RSR)). The comparison of performance metrics shows that MLPANN models achieved approximately 54% lower error metrics than RBF models. The performance of the developed models was further examined using rank analysis, Taylor and Scaled Percentage Error (SPE) plots. Rank analysis and Taylor and SPE graphs showed that MLPANN models predicted the values of four radiological risk parameters of thermal waters more correctly than RBFANN models. This study demonstrates that MLPANNs significantly outperformed RBFANNs in predicting the radiological risks of thermal waters in Türkiye. Full article
(This article belongs to the Special Issue Measurement and Assessment of Environmental Radioactivity)
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39 pages, 10741 KB  
Article
Modeling the Dynamics of the Jebel Zaghouan Karst Aquifer Using Artificial Neural Networks: Toward Improved Management of Vulnerable Water Resources
by Emna Gargouri-Ellouze, Tegawende Arnaud Ouedraogo, Fairouz Slama, Jean-Denis Taupin, Nicolas Patris and Rachida Bouhlila
Hydrology 2025, 12(10), 250; https://doi.org/10.3390/hydrology12100250 - 26 Sep 2025
Viewed by 548
Abstract
Karst aquifers are critical yet vulnerable water resources in semi-arid Mediterranean regions, where structural complexity, nonlinearity, and delayed hydrological responses pose significant modeling challenges under increasing climatic and anthropogenic pressures. This study examines the Jebel Zaghouan aquifer in northeastern Tunisia, aiming to simulate [...] Read more.
Karst aquifers are critical yet vulnerable water resources in semi-arid Mediterranean regions, where structural complexity, nonlinearity, and delayed hydrological responses pose significant modeling challenges under increasing climatic and anthropogenic pressures. This study examines the Jebel Zaghouan aquifer in northeastern Tunisia, aiming to simulate its natural discharge dynamics prior to intensive exploitation (1915–1944). Given the fragmented nature of historical datasets, meteorological inputs (rainfall, temperature, and pressure) were reconstructed using a data recovery process combining linear interpolation and statistical distribution fitting. The hyperparameters of the artificial neural network (ANN) model were optimized through a Bayesian search. Three deep learning architectures—Multi-Layer Perceptron (MLP), Convolutional Neural Network (CNN), and Long Short-Term Memory (LSTM)—were trained to model spring discharge. Model performance was evaluated using Kling–Gupta Efficiency (KGE′), Nash–Sutcliffe Efficiency (NSE), and R2 metrics. Hydrodynamic characterization revealed moderate variability and delayed discharge response, while isotopic analyses (δ18O, δ2H, 3H, 14C) confirmed a dual recharge regime from both modern and older waters. LSTM outperformed other models at the weekly scale (KGE′ = 0.62; NSE = 0.48; R2 = 0.68), effectively capturing memory effects. This study demonstrates the value of combining historical data rescue, ANN modeling, and hydrogeological insight to support sustainable groundwater management in data-scarce karst systems. Full article
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16 pages, 14433 KB  
Article
Groundwater Fluoride Prediction for Sustainable Water Management: A Comparative Evaluation of Machine Learning Approaches Enhanced by Satellite Embeddings
by Yunbo Wei, Rongfu Zhong and Yun Yang
Sustainability 2025, 17(18), 8505; https://doi.org/10.3390/su17188505 - 22 Sep 2025
Cited by 1 | Viewed by 460
Abstract
Groundwater fluoride contamination poses a significant threat to sustainable water resources and public health, yet conventional water quality analysis is both time-consuming and costly, making large-scale, sustainable monitoring challenging. Machine learning methods offer a promising, cost-effective, and sustainable alternative for assessing the spatial [...] Read more.
Groundwater fluoride contamination poses a significant threat to sustainable water resources and public health, yet conventional water quality analysis is both time-consuming and costly, making large-scale, sustainable monitoring challenging. Machine learning methods offer a promising, cost-effective, and sustainable alternative for assessing the spatial distribution of fluoride. This study aimed to develop and compare the performance of Random Forest (RF), Support Vector Machine (SVM), and Artificial Neural Network (ANN) models for predicting groundwater fluoride contamination in the Datong Basin with the help of satellite embeddings from the AlphaEarth Foundation. Data from 391 groundwater sampling points were utilized, with the dataset partitioned into training (80%) and testing (20%) sets. The ANOVA F-value of each feature was calculated for feature selection, identifying surface elevation, pollution, population, evaporation, vertical distance to the rivers, distance to the Sanggan river, and nine extra bands from the satellite embeddings as the most relevant input variables. Model performance was evaluated using the confusion matrix and the area under the receiver operating characteristic curve (ROC-AUC). The results showed that the SVM model demonstrated the highest ROC-AUC (0.82), outperforming the RF (0.80) and MLP (0.77) models. The introduction of satellite embeddings improved the performance of all three models significantly, with the prediction errors decreasing by 13.8% to 23.3%. The SVM model enhanced by satellite embeddings proved to be a robust and reliable tool for predicting groundwater fluoride contamination, highlighting its potential for use in sustainable groundwater management. Full article
(This article belongs to the Topic Water Management in the Age of Climate Change)
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17 pages, 1671 KB  
Article
Early-Stage Prediction of Steel Weight in Industrial Buildings Using Neural Networks
by Johnny Setiawan, Ridho Bayuaji, Mohammad Arif Rohman and Delima Canny Valentine Simarmata
Symmetry 2025, 17(9), 1579; https://doi.org/10.3390/sym17091579 - 22 Sep 2025
Viewed by 363
Abstract
In industrial building projects, steel is the main material used to create sturdy structures that have large open spaces without many columns in the center of the building. To estimate the cost of constructing a building before it enters the detailed design stage, [...] Read more.
In industrial building projects, steel is the main material used to create sturdy structures that have large open spaces without many columns in the center of the building. To estimate the cost of constructing a building before it enters the detailed design stage, engineers and stakeholders must have the right tools and guidelines. Steel is an important construction material used at high volumes in industrial buildings, and it plays a significant role in determining the total cost of a project. This study develops and evaluates an artificial neural network (ANN) model based on multilayer perceptron (MLP) to predict the weight of steel structures in industrial buildings. The data collected include actual projects from 180 industrial building projects, using parameters that influence the weight of steel. The findings show that the ANN method can accurately estimate the weight of steel at an early stage in the building project, even before the detailed design phase. It was found that ANN has the ability to predict the weight of steel for industrial buildings with an excellent degree of accuracy, with a coefficient of correlation (R2) of 94.85% and prediction accuracy (PA) of 94.23%. This indicates that the relationship between the independent and dependent variables of the developed models is good and the predicted values from the forecast model fit with the real-life data. Full article
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32 pages, 1727 KB  
Article
Client-Oriented Highway Construction Cost Estimation Models Using Machine Learning
by Fani Antoniou and Konstantinos Konstantinidis
Appl. Sci. 2025, 15(18), 10237; https://doi.org/10.3390/app151810237 - 19 Sep 2025
Viewed by 718
Abstract
Accurate cost estimation during the conceptual and feasibility phase of highway projects is essential for informed decision making by public contracting authorities. Existing approaches often rely on pavement cross-section descriptors, general project classifications, or quantity estimates of major work categories that are not [...] Read more.
Accurate cost estimation during the conceptual and feasibility phase of highway projects is essential for informed decision making by public contracting authorities. Existing approaches often rely on pavement cross-section descriptors, general project classifications, or quantity estimates of major work categories that are not reliably available at the early planning stage, while focusing on one or more key asset categories such as roadworks, bridges or tunnels. This study makes a novel contribution to both scientific literature and practice by proposing the first early-stage highway construction cost estimation model that explicitly incorporates roadworks, interchanges, tunnels and bridges, using only readily available or easily derived geometric characteristics. A comprehensive and practical approach was adopted by developing and comparing models across multiple machine learning (ML) methods, including Multilayer Perceptron-Artificial Neural Network (MLP-ANN), Radial Basis Function-Artificial Neural Network (RBF-ANN), Multiple Linear Regression (MLR), Random Forests (RF), Support Vector Regression (SVR), XGBoost Technique, and K-Nearest Neighbors (KNN). Results demonstrate that the MLR model based on six independent variables—mainline length, service road length, number of interchanges, total area of structures, tunnel length, and number of culverts—consistently outperformed more complex alternatives. The full MLR model, including its coefficients and standardized parameters, is provided, enabling direct replication and immediate use by contracting authorities, hence supporting more informed decisions on project funding and procurement. Full article
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19 pages, 1227 KB  
Article
Hierarchical Sectorized ANN Model for DoA Estimation in Smart Textile Wearable Antenna Array Under Strong Noise Conditions
by Zoran Stanković, Olivera Pronić-Rančić and Nebojša Dončov
Sensors 2025, 25(18), 5704; https://doi.org/10.3390/s25185704 - 12 Sep 2025
Viewed by 341
Abstract
A novel hierarchical sectorized neural network module for a fast direction of arrival (DoA) estimation (HSNN-DoA) of the signal received by a textile wearable antenna array (TWAA) under strong noise conditions is presented. The developed DoA module accounts for variations in antenna element [...] Read more.
A novel hierarchical sectorized neural network module for a fast direction of arrival (DoA) estimation (HSNN-DoA) of the signal received by a textile wearable antenna array (TWAA) under strong noise conditions is presented. The developed DoA module accounts for variations in antenna element gain, inter-element spacing, and resonant frequencies under the conditions of textile crumpling caused by the motion of the TWAA wearer. The proposed model consists of a sector identification phase, which aims to determine the spatial sector in which the radio gateway (RG) is currently located based on the elements of the spatial correlation matrix of the signal sampled by the TWAA, and a DoA estimation phase, which aims to accurately determine the angular position of the RG in the azimuthal plane. The architecture of the HSNN-DoA module, with different time window lengths in which angular position of RG is recorded, is investigated and compared with the DoA module based on a stand-alone MLP network and the corresponding Root-MUSIC DoA module in terms of accuracy and speed of DoA estimation under variable noise conditions. Full article
(This article belongs to the Section Wearables)
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13 pages, 1842 KB  
Article
Artificial Neural Network Model for Predicting Local Equilibrium Scour Depth at Pile Groups in Steady Currents
by Xinao Zhao, Ping Dong, Yan Li, Yan Zhou, Xiaoying Zhao, Qing Wang and Chao Zhan
J. Mar. Sci. Eng. 2025, 13(9), 1742; https://doi.org/10.3390/jmse13091742 - 10 Sep 2025
Viewed by 299
Abstract
Piles are common support elements for marine and coastal structures. The scour around pile foundations caused by currents is a major threat to the stability and safety of these structures. The empirical equations commonly used for estimating the equilibrium scour depth around pile [...] Read more.
Piles are common support elements for marine and coastal structures. The scour around pile foundations caused by currents is a major threat to the stability and safety of these structures. The empirical equations commonly used for estimating the equilibrium scour depth around pile groups are limited in their predicative capability, especially when the current approaches the pile group at an angle. This study applies a Multi-Layer Perceptron Backpropagation (MLP/BP) neural network to develop a general model for predicting the local maximum equilibrium scour depth around pile groups in steady currents. The input parameters for the model include all relevant non-dimensional hydrodynamic and structural variables taking full account of the effects of the pile group arrangement and its orientation relative to the approaching current. The model’s performance was evaluated by comparing its predictions against those generated by multiple other machine learning methods, as well as against results from widely used empirical formulas. A comprehensive sensitivity analysis is carried out to determine the importance ranking of the input parameters on model accuracy. Full article
(This article belongs to the Section Ocean Engineering)
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18 pages, 2654 KB  
Article
Modeling the Electrochemical Synthesis of Zinc Oxide Nanoparticles Using Artificial Neural Networks
by Sławomir Francik, Michał Hajos, Beata Brzychczyk, Jakub Styks, Renata Francik and Zbigniew Ślipek
Materials 2025, 18(17), 4187; https://doi.org/10.3390/ma18174187 - 6 Sep 2025
Viewed by 824
Abstract
A neural model was developed to predict the distribution of ZnO nanoparticles obtained by electrochemical synthesis. It is a three-layer multilayer perceptron (MLP) artificial neural network (ANN) with five neurons in the input layer, eight neurons in the hidden layer, and one neuron [...] Read more.
A neural model was developed to predict the distribution of ZnO nanoparticles obtained by electrochemical synthesis. It is a three-layer multilayer perceptron (MLP) artificial neural network (ANN) with five neurons in the input layer, eight neurons in the hidden layer, and one neuron in the output layer. This network has a hyperbolic tangent activation function for the neurons in the hidden layer and an exponential activation function for the neuron in the output layer. The input (independent) variables are particle size (nm), solvent type, and temperature (°C), and the output (dependent) variable is fraction share (%). The best neural model (ann08) has a root mean square error (RMSE) 0.84% for the training subset, 0.98% for the testing subset, and 1.27% for the validation subset. The RMSE values are therefore small, which enables practical use of the ANN model. Full article
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14 pages, 1938 KB  
Article
Daily Reservoir Evaporation Estimation Using MLP and ANFIS: A Comparative Study for Sustainable Water Management
by Funda Dökmen, Çiğdem Coşkun Dilcan and Yeşim Ahi
Water 2025, 17(17), 2623; https://doi.org/10.3390/w17172623 - 5 Sep 2025
Cited by 1 | Viewed by 900
Abstract
Reservoir evaporation is a vital component of the hydrological cycle and presents considerable challenges for sustainable water management, especially in arid and semi-arid regions. This study assesses the effectiveness of two Artificial Intelligence (AI) methods: Multilayer Perceptron (MLP) and Adaptive Neuro-Fuzzy Inference System [...] Read more.
Reservoir evaporation is a vital component of the hydrological cycle and presents considerable challenges for sustainable water management, especially in arid and semi-arid regions. This study assesses the effectiveness of two Artificial Intelligence (AI) methods: Multilayer Perceptron (MLP) and Adaptive Neuro-Fuzzy Inference System (ANFIS), a combination ANN with fuzzy logic, in estimating daily evaporation from a large reservoir in a semi-arid region. Using eight years of hydrometeorological data from a nearby station, the study employed the ReliefF algorithm as a feature selection method for relevant input variables. The dataset was divided into training, validation, and testing subsets with 5% and 10% validation ratios, using four train–test splits of 70:30, 75:25, 80:20, and 85:15. Various training algorithms (e.g., Levenberg–Marquardt) and membership functions (e.g., generalized bell-shaped functions) were tested for both models. MLP consistently outperformed ANFIS on the test sets, showing higher R2 and lower RMSE values. In the best-performing 70:30 split, MLP achieved an R2 of 0.8069 and RMSE of 0.0923, compared to ANFIS with an R2 of 0.3192 and RMSE of 0.2254. The findings highlight the AI-based approaches’ potential to support improved evaporation forecasting and integration into decision support tools for water resource planning amid changing climatic conditions. Full article
(This article belongs to the Special Issue Machine Learning Applications in the Water Domain)
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23 pages, 3031 KB  
Article
Integrated Capuchin Search Algorithm-Optimized Multilayer Perceptron for Robust and Precise Prediction of Blast-Induced Airblast in a Blasting Mining Operation
by Kesalopa Gaopale, Takashi Sasaoka, Akihiro Hamanaka and Hideki Shimada
Geosciences 2025, 15(8), 306; https://doi.org/10.3390/geosciences15080306 - 6 Aug 2025
Viewed by 566
Abstract
Blast-induced airblast poses a significant environmental and operational issue for surface mining, affecting safety, regulatory adherence, and the well-being of surrounding communities. Despite advancements in machine learning methods for predicting airblast, present studies neglect essential geomechanical characteristics, specifically rock mass strength (RMS), which [...] Read more.
Blast-induced airblast poses a significant environmental and operational issue for surface mining, affecting safety, regulatory adherence, and the well-being of surrounding communities. Despite advancements in machine learning methods for predicting airblast, present studies neglect essential geomechanical characteristics, specifically rock mass strength (RMS), which is vital for energy transmission and pressure-wave attenuation. This paper presents a capuchin search algorithm-optimized multilayer perceptron (CapSA-MLP) that incorporates RMS, hole depth (HD), maximum charge per delay (MCPD), monitoring distance (D), total explosive mass (TEM), and number of holes (NH). Blast datasets from a granite quarry were utilized to train and test the model in comparison to benchmark approaches, such as particle swarm optimized artificial neural network (PSO-ANN), multivariate regression analysis (MVRA), and the United States Bureau of Mines (USBM) equation. CapSA-MLP outperformed PSO-ANN (RMSE = 1.120, R2 = 0.904 compared to RMSE = 1.284, R2 = 0.846), whereas MVRA and USBM exhibited lower accuracy. Sensitivity analysis indicated RMS as the main input factor. This study is the first to use CapSA-MLP with RMS for airblast prediction. The findings illustrate the significance of metaheuristic optimization in developing adaptable, generalizable models for various rock types, thereby improving blast design and environmental management in mining activities. Full article
(This article belongs to the Section Geomechanics)
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11 pages, 551 KB  
Article
Artificial Neural Network for the Fast Screening of Samples from Suspected Urinary Tract Infections
by Cristiano Ialongo, Marco Ciotti, Alfredo Giovannelli, Flaminia Tomassetti, Martina Pelagalli, Stefano Di Carlo, Sergio Bernardini, Massimo Pieri and Eleonora Nicolai
Antibiotics 2025, 14(8), 768; https://doi.org/10.3390/antibiotics14080768 - 30 Jul 2025
Viewed by 626
Abstract
Background: Urine microbial analysis is a frequently requested test that is often associated with contamination during specimen collection or storage, which leads to false-positive diagnoses and delayed reporting. In the era of digitalization, machine learning (ML) can serve as a valuable tool to [...] Read more.
Background: Urine microbial analysis is a frequently requested test that is often associated with contamination during specimen collection or storage, which leads to false-positive diagnoses and delayed reporting. In the era of digitalization, machine learning (ML) can serve as a valuable tool to support clinical decision-making. Methods: This study investigates the application of a simple artificial neural network (ANN) to pre-identify negative and contaminated (false-positive) specimens. An ML model was developed using 8181 urine samples, including cytology, dipstick tests, and culture results. The dataset was randomly split 2:1 for training and testing a multilayer perceptron (MLP). Input variables with a normalized importance below 0.2 were excluded. Results: The final model used only microbial and either urine color or urobilinogen pigment analysis as inputs; other physical, chemical, and cellular parameters were omitted. The frequency of positive and negative specimens for bacteria was 6.9% and 89.6%, respectively. Contaminated specimens represented 3.5% of cases and were predominantly misclassified as negative by the MLP. Thus, the negative predictive value (NPV) was 96.5% and the positive predictive value (PPV) was 87.2%, leading to 0.82% of the cultures being unnecessary microbial cultures (UMC). Conclusions: These results suggest that the MLP is reliable for screening out negative specimens but less effective at identifying positive ones. In conclusion, ANN models can effectively support the screening of negative urine samples, detect clinically significant bacteriuria, and potentially reduce unnecessary cultures. Incorporating morphological information data could further improve the accuracy of our model and minimize false negatives. Full article
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