Special Issue "Phage Lytic Enzymes and Their Applications"
Deadline for manuscript submissions: closed (30 November 2018).
Interests: endolysins; endolysin engineering; synthetic biology of modular proteins
Lytic enzymes encoded by bacteriophages are increasingly recognized as highly effective antibacterials with broad applications in (veterinary) medicine, diagnostics, and food conservation. Although diverse in structure and enzymatic specificity, they share a rapid and bactericidal killing mechanism through peptidoglycan degradation followed by osmotic lysis. Virtually each pathogen can be killed by this novel class of antibacterials. Significant progress has been realized in (pre)clinical analysis, formulation and administration routes of phage-encoded lytic enzymes. The last decade protein engineering has been extensively applied to improve their properties or to expand their applications to Gram-negative pathogens. In addition, single domains derived from phage-encoded lytic enzymes are increasingly used in diverse applications.
In this Special Issue of Viruses, we aim for research papers that contribute to an improved understanding of phage-derived lytic enzymes or that report on the development of phage-derived lytic enzymes (or their domains) for diverse applications.
Prof. Dr. Yves Briers
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Viruses is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- peptidoglycan degradation
- (pre)clinical analysis
- enzyme engineering