Special Issue "Viruses and Autophagy"
Deadline for manuscript submissions: closed (31 July 2017).
Interests: antigen processing; LC3- associated phagocytosis; viral regulation of autophagy; MHC restricted antigen presentation; Atg supported exocytosis
Autophagy is a group of cytoplasmic degradation pathways that utilize lysosmal hydrolysis to recycle intracellular organelles and macromolecules. More than 30 autophagy related gene (atg) products remodel cellular membranes to achieve this function. Viruses as some of the most successful intracellular pathogens face destruction by these pathways and have developed various strategies to inhibit autophagy or utilize autophagic membranes for their own replication. These include the assembly of their replication machineries on autophagic membranes and recruiting them for viral envelope acquisition. During viral evasion from autophagy and hijacking of autophagic membranes not only canonical autophagy functions of atgs are used, but also alternative roles of atgs in other membrane remodelling pathways.
The series of reviews and primary research articles in this special issue is dedicated to the rapidly growing field of interactions between the autophagic machinery and viruses. This series might include articles on viral restriction by autophagy, viral escape mechanisms from autophagy, utilization of autophagic membranes during viral replication, regulation of innate and adaptive immune responses to viruses by autophagy and utilization of autophagy for vaccination against viral diseases. It will provide a valuable overview over the many mechanisms, by which viruses interact with autophagy, and will hopefully point out new exciting research areas of how to study autophagy with viruses as well as how to use autophagy for therapeutic intervention against viral diseases.
Prof. Dr. Christian Münz
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Viruses is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- viral restriction by autophagy
- intrinsic immunity by autophagy
- viral immune escape from autophagy
- viral exocytosis via autophagy
- autophagic membranes in viral envelopes
- LC3-associated phagocytosis during viral infections
- autophagic regulation of cytokine production during viral infections
- regulation of adaptive anti-viral immune responses by autophagy