Development of Diagnostics and Therapeutic Interventions for Viral Infections of the Central Nervous System
A special issue of Viruses (ISSN 1999-4915). This special issue belongs to the section "Viral Immunology, Vaccines, and Antivirals".
Deadline for manuscript submissions: 30 September 2025 | Viewed by 128
Special Issue Editors
Interests: virus infection of the central nervous system (CNS); viral-mediated neurological diseases
Special Issue Information
Dear Colleagues,
Each year, thousands of people suffer from viral encephalitis, with many cases attributed to infections with herpes simplex virus (HSV), varicella-zoster virus (VSV), enteroviruses, or arthropod-borne viruses. It is estimated that as many as 40% of viral encephalitis cases go undiagnosed. Two major limitations in treating viral encephalitis are the lack of specific, timely diagnostics for the causative agent as well as effective therapeutic interventions. Diagnosis often relies on a combination of molecular and serologic techniques. No multiplex assays are commercially available, necessitating specimens to be tested individually to a single organism which can be time-consuming leading to delays in administration of therapeutic interventions. Besides acyclovir treatment for patients with HSV infections, few therapeutics are available to treat patients with other viral infections. Treatment in these circumstances may rely on supportive care.
In this Special Issue, we will focus on the most recent advances in the development of timely diagnostics for the determination of viral encephalitis and/or identifying the causative viral agent. We will also examine progress on new therapeutics for the treatment of either specific viruses or encephalitis in general. We hope this issue will be a mix of both new and exciting research publications as well as reviews and thought-provoking opinion articles.
Dr. Karin E. Peterson
Dr. Amanda E. Calvert
Guest Editors
Manuscript Submission Information
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Keywords
- encephalitis
- arbovirus
- diagnosis
- treatment
- neurovirology
- antibody therapeutics
- agnostic therapeutics
- point of care diagnostics
- rapid diagnostics
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