Anesthesiology and Intensive Care in Animal Surgical Patients

A special issue of Veterinary Sciences (ISSN 2306-7381).

Deadline for manuscript submissions: 20 June 2026 | Viewed by 1127

Special Issue Editor


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Guest Editor
Department of Surgery, School of Veterinary Medicine and Animal Science, University of São Paulo, 87 Professor Orlando Marques Paiva Ave., São Paulo 05508-270, SP, Brazil
Interests: mechanical ventilation; anesthesia; pain; intensive care

Special Issue Information

Dear Colleagues,

The Special Issue focuses on the critical aspects of anesthesia management and postoperative care in veterinary surgical patients, emphasizing developments and updated practices that have emerged over the past 5–8 years and key cross‑overs from human anesthesia and analgesia. It will encompass a broad scope, addressing various anesthetic techniques, mechanical ventilation, monitoring strategies, pain control, and intensive‑care protocols tailored to different species and surgical procedures. This Special Issue seeks to enhance understanding of anesthetic practices and their impact on the outcomes of surgical interventions in animals, ultimately contributing to improved patient safety and recovery.

This Special Issue will usefully supplement the existing literature by providing updated insights into research articles and literature reviews that bridge gaps in current knowledge. By highlighting innovative practices and recent advancements in anesthesiology and critical care, this Special Issue will serve as a valuable, up‑to‑date resource for veterinary professionals seeking to refine their skills and enhance patient care.

Dr. Aline Ambrósio
Guest Editor

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Keywords

  • anesthesiology
  • intensive care
  • mechanical ventilation
  • pain
  • anesthetic techniques
  • postoperative care

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Published Papers (1 paper)

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Research

12 pages, 487 KB  
Article
Dose–Response Evaluation of Sugammadex for Reversal of Deep Rocuronium-Induced Neuromuscular Block in Cats
by Natália Mesquita Cesnik, Karina D’Angelo Campos, Jéssica Sperandio Cavaco, Carolina Soares Navarro, André Gustavo Alves Holanda, Julia Maria Matera and Aline Magalhães Ambrósio
Vet. Sci. 2025, 12(12), 1135; https://doi.org/10.3390/vetsci12121135 - 29 Nov 2025
Viewed by 618
Abstract
Background: Sugammadex is a selective γ-cyclodextrin compound that encapsulates steroidal neuromuscular blocking agents such as rocuronium, allowing rapid and predictable recovery from neuromuscular block (NMB). However, dose–response information in feline patients remains limited. Methods: In this prospective, randomized, and blinded experimental study, three [...] Read more.
Background: Sugammadex is a selective γ-cyclodextrin compound that encapsulates steroidal neuromuscular blocking agents such as rocuronium, allowing rapid and predictable recovery from neuromuscular block (NMB). However, dose–response information in feline patients remains limited. Methods: In this prospective, randomized, and blinded experimental study, three intravenous doses of sugammadex (2, 4, and 8 mg kg−1) were compared for the reversal of profound rocuronium-induced NMB (0.6 mg kg−1) in thirty adult ASA I cats anesthetized with sevoflurane. Neuromuscular function was continuously assessed using acceleromyography (train-of-four stimulation). The onset and recovery times for T1/T0 ratios of 25–90%, T4/T1 ratios, and recovery index were measured, along with cardiovascular and respiratory parameters. Results: Sugammadex shortened the recovery time in a dose-dependent manner. The mean time to achieve T1/T0 = 90% was 519 s (2 mg kg−1), 300 s (4 mg kg−1), or 256.8 s (8 mg kg−1). The 43-s difference between the two higher doses was not statistically significant (p = 0.317) and, therefore, not clinically relevant. Greater interindividual variability in the reversal time was observed at a dose of 4 mg kg−1. One cat in this group experienced transient recurarization, and no adverse cardiovascular effects were detected. Conclusions: Both 4 and 8 mg kg−1 of sugammadex produced rapid and complete reversal of profound rocuronium-induced NMB in sevoflurane-anesthetized cats without hemodynamic compromise. These results apply to healthy ASA I cats, and further studies are warranted in animals with systemic disease. Full article
(This article belongs to the Special Issue Anesthesiology and Intensive Care in Animal Surgical Patients)
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