Mammary Development and Health: Challenges and Advances

A special issue of Veterinary Sciences (ISSN 2306-7381). This special issue belongs to the section "Anatomy, Histology and Pathology".

Deadline for manuscript submissions: 28 February 2026 | Viewed by 643

Special Issue Editors


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Guest Editor
College of Veterinary Medicine, Shandong Agricultural University, Tai’an 271018, China
Interests: lactation physiology; nutritional and metabolic diseases; mammary development

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Guest Editor
College of Veterinary Medicine, Shandong Agricultural University, Tai’an 271018, China
Interests: mammary development; lactation physiology; nutritional regulation

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Guest Editor
College of Animal Science and Technology, Shandong Agricultural University, Tai’an 271018, China
Interests: host–microbiota interaction; ruminant nutrition; rumen phage; gut microbiota

Special Issue Information

Dear Colleagues,

As a unique organ in mammals, the mammary gland’s efficient development and healthy lactation are pivotal for determining both the economic performance and reproductive capability of livestock. Mammary development commences during the embryonic stage, progresses through extensive ductal branching in puberty, and culminates in the formation of alveoli during gestation, ultimately reaching functional maturity during lactation. Throughout this prolonged development process, the mammary gland is intricately regulated by nutritional, environmental, and various other factors. Once lactation begins—particularly in ruminants—mammary diseases, most notably mastitis, emerge as the most prevalent and challenging issues, with prognoses influenced by pathogenic microorganisms, environmental conditions, and stress factors. Consequently, ensuring optimal mammary development before lactation, while effectively reducing disease incidence during lactation and sustaining lactational performance, represents a critical scientific challenge. This Special Issue warmly invites publication submissions addressing any aspect of “mammary gland developmental regulation” and “mammary disease prevention and treatment” in both livestock and model organisms. We hope that this Special Issue will further stimulate deep interdisciplinary collaboration among scientists in lactation physiology, developmental biology, microbiology, and related fields.

Prof. Dr. Qiuling Hou
Dr. Xusheng Dong
Dr. Yingyu Mu
Guest Editors

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Keywords

  • mammary
  • mammary development
  • lactation physiology
  • mastitis
  • pathogenic microorganism
  • mammary disease
  • livestock
  • model animal

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Published Papers (1 paper)

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Review

42 pages, 1210 KB  
Review
Comprehensive Prevention and Control of Mastitis in Dairy Cows: From Etiology to Prevention
by Wenjing Yu, Zixuan Zhang, Zhonghua Wang, Xueyan Lin, Xusheng Dong and Qiuling Hou
Vet. Sci. 2025, 12(9), 800; https://doi.org/10.3390/vetsci12090800 - 23 Aug 2025
Viewed by 545
Abstract
Mastitis, an inflammatory disease caused by the invasion of various pathogenic microorganisms into mammary gland tissue, is a core health issue plaguing the global dairy industry. The consequences of this disease are manifold. In addition to directly compromising the health and welfare of [...] Read more.
Mastitis, an inflammatory disease caused by the invasion of various pathogenic microorganisms into mammary gland tissue, is a core health issue plaguing the global dairy industry. The consequences of this disease are manifold. In addition to directly compromising the health and welfare of dairy cows, it also precipitates a substantial decline in lactation function, a precipitous drop in raw milk production, and alterations in milk composition (e.g., increased somatic cell counts and imbalanced ratios of milk protein to fat). These changes result in a marked degradation of milk quality and safety, and in turn, engender significant economic losses for the livestock industry. Therefore, the establishment and implementation of a comprehensive prevention and control system is a key strategy to effectively curb the occurrence of mastitis, reduce its incidence rate, and minimise economic losses. This review systematically explores the complex etiological factors and pathogenic mechanisms of mastitis in dairy cows, and summarises various diagnostic methods, including milk apparent indicators monitoring, pathogen detection, physiological parameter monitoring, omics technologies, and emerging technologies. Furthermore, it undertakes an analysis of treatment protocols for mastitis in dairy cows, with a particular emphasis on the significance of rational antibiotic use and alternative therapies. Moreover, it delineates preventive measures encompassing both environmental and hygiene management, and dairy cow health management. The objective of this paper is to provide a comprehensive and scientific theoretical basis and practical guidance for dairy farming practices. This will help to improve the health of dairy cows, ensure a stable supply of high-quality dairy products, and promote the sustainable and healthy development of the dairy farming industry. Full article
(This article belongs to the Special Issue Mammary Development and Health: Challenges and Advances)
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