Advances in Research on Animal Infectious Diseases

A special issue of Veterinary Sciences (ISSN 2306-7381).

Deadline for manuscript submissions: closed (20 January 2023) | Viewed by 2242

Special Issue Editors

College of Veterinary Medicine, Yangzhou University, Yangzhou 225012, China
Interests: zoonotic pathogens; epidemiology; veterinary immunology
College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, China
Interests: mucosal immunology; avian RNA virus; dendritic cells; RNA interference

Special Issue Information

Dear Colleagues,

Animal infectious disease, which is caused by pathogenic microorganisms, can lead to major economic losses in the animal raising industry, especially in the porcine and poultry industry. There are many animal infectious diseases with high morbidity, including viral infectious diseases such as African swine fever (ASF), porcine pseudorabies, porcine reproductive and respiratory syndrome (PRRS), porcine parvovirus disease (PPD), porcine epidemic diarrhea (PED), Newcastle disease (ND), avian influenza (AI), infectious bronchitis (IB), infectious laryngotracheitis (ILT), Marek’s disease (MD), infectious bursal disease (IBD), avian leukosis, etc.; as well as bacterial infectious diseases such as colibacillosis, salmonellosis, pasteurellosis, streptococcosis, etc. Animal infectious diseases may not only cause animal infection and death, but some zoonotic diseases also introduce serious threats to human health. Currently, emerging and re-emerging infectious diseases pose a new challenge for veterinarians and researchers. However, the epidemic patterns, pathogenesis, and immune regulation mechanism of many animal infectious diseases have not been thoroughly clarified. Therefore, this Special Issue on the “Epidemiology, Pathogenesis, and Immune Mechanism of Animal Infectious Disease” welcomes all types of manuscripts (e.g., reviews, research articles, and short communications), covering the latest findings regarding animal infectious diseases and providing novel knowledge in this research area.

Topics of interest include but are not limited to:

  • Epidemiology
  • Pathogenic mechanisms of veterinary pathogens
  • Immune regulation mechanisms of veterinary pathogens
  • Zoonosis

Dr. Tao Qin
Dr. Jian Lin
Guest Editors

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Keywords

  • epidemiology
  • emerging animal infectious diseases
  • pathogenicity
  • immunity and infection
  • vaccines
  • porcine infectious diseases
  • poultry infectious diseases

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Published Papers (1 paper)

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Research

17 pages, 1752 KiB  
Article
Preliminary Study on the Host Response to Bivalent and Monovalent Autogenous Vaccines against Mycoplasma agalactiae in Dairy Sheep
by Hany A. Hussein, Marco Tolone, Lucia Condorelli, Paola Galluzzo, Roberto Puleio, Irene Vazzana, Maria Luisa Scatassa, Gavino Marogna, Santino Barreca, Guido Ruggero Loria, Lucia Galuppo and Sergio Migliore
Vet. Sci. 2022, 9(12), 651; https://doi.org/10.3390/vetsci9120651 - 22 Nov 2022
Cited by 1 | Viewed by 1690
Abstract
In Italy, dairy sheep farming represents a vital agro-industry sector, but it is still challenged by contagious agalactia (CA), which is endemic there, and vaccination is the most economical and sustainable tool for control. This study aimed to evaluate the combined Mycoplasma agalactiae [...] Read more.
In Italy, dairy sheep farming represents a vital agro-industry sector, but it is still challenged by contagious agalactia (CA), which is endemic there, and vaccination is the most economical and sustainable tool for control. This study aimed to evaluate the combined Mycoplasma agalactiae (Ma)-Staphylococcus aureus (Sa) vaccine (Ma–Sa) against the Ma monovalent vaccine in ewes. Twelve primiparous Ma-free ewes were randomly grouped into three equal groups: first, the control group injected with placebo, second, the group vaccinated with the Ma monovalent vaccine, and third, the group vaccinated with Ma–Sa combined vaccine, with two S/C doses at 45-day intervals. The animals were examined for serological, hematological, and somatic cell count (SCC) changes for 17 successive weeks. A significant increase in anti-Ma antibody mean titers, leukocytes, and platelets was observed in the vaccinated animals, with the highest values in those who received the combined vaccine. Neutrophils were high only in the animals who received the combined vaccine. SCC was lower in the vaccinated animals during the first six weeks. This study concludes that the combined Ma–Sa vaccines enhance immune response and potentiate its efficacy against Ma. This improvement might be attributed to the sensitization/activation effect of S. aureus on platelets, which are recoded to act as a key regulator for the coordination of all components of the innate immune system. Even though this study included a small number of animals, its findings about the potentialities of this inactivated vaccine in the control of CA are strongly encouraging. Further confirmation might be needed through additional replicates and a challenge study is needed before proceeding with widespread use. Full article
(This article belongs to the Special Issue Advances in Research on Animal Infectious Diseases)
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