Animal Clinical Pathology: Focus on Hematology and Biochemical Diagnostics

A special issue of Veterinary Sciences (ISSN 2306-7381). This special issue belongs to the section "Veterinary Biomedical Sciences".

Deadline for manuscript submissions: 10 September 2025 | Viewed by 2001

Special Issue Editor


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Department of Veterinary Sciences, Animal and Veterinary Research Centre (CECAV), University of Trás-os-Montes e Alto Douro, 5001-801 Vila Real, Portugal
Interests: immunohematology; transfusion medicine; feline blood types
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Special Issue Information

Dear Colleagues,

Animal clinical pathology is a crucial field in veterinary medicine that focuses on the diagnosis and treatment of diseases in animals through the analysis of blood and other body fluids. Hematology and biochemical diagnostics are two key components of animal clinical pathology that play a vital role in understanding the health status of animals.

Hematology involves the study of blood and its components, including red blood cells (RBCs), white blood cells (WBCs), and platelets. It is an essential tool with which veterinarians can assess the overall health of an animal and diagnose conditions such as anemia, infections, and clotting disorders. Hematology is also essential for monitoring the progression of diseases and evaluating the response to treatment.

Biochemical diagnostics, on the other hand, focuses on the analysis of biochemical markers in body fluids such as blood serum or plasma. These markers provide valuable information about the function of various organs and body systems.

Understanding hematology and biochemical diagnostics is crucial in the effective diagnosis and management of animal health. These tests provide valuable insights into the physiological and pathological states of animals, enabling timely and accurate medical interventions.

We invite researchers, clinicians, and experts in the field to contribute original research articles, reviews, and case studies that focus on all areas of animal clinical pathology.

Prof. Dr. Ana Cristina Silvestre Ferreira
Guest Editor

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Keywords

  • animal clinical pathology

  • hematology
  • biochemical diagnostics
  • veterinary medicine
  • disease diagnosis and treatment
  • biomarkers
  • coagulation
  • laboratory techniques

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Published Papers (1 paper)

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Research

7 pages, 225 KiB  
Article
Dog Blood Type DEA 1 in Two Municipalities of Luanda Province of Angola (Sub-Saharan Africa)
by Ana C. Silvestre-Ferreira, Hugo Vilhena, Ana C. Oliveira, José R. Mendoza, Maria Garcia Aura and Josep Pastor
Vet. Sci. 2024, 11(9), 449; https://doi.org/10.3390/vetsci11090449 - 22 Sep 2024
Viewed by 1058
Abstract
In dogs, the risk of an acute hemolytic transfusion reaction at the first transfusion is negligible; however, mismatched transfusions may produce alloimmunization. To avoid fatal acute hemolytic reactions in subsequent blood transfusions, it is important to recognize blood groups and to blood type [...] Read more.
In dogs, the risk of an acute hemolytic transfusion reaction at the first transfusion is negligible; however, mismatched transfusions may produce alloimmunization. To avoid fatal acute hemolytic reactions in subsequent blood transfusions, it is important to recognize blood groups and to blood type both the donor and the recipient. Prevalence of dog blood groups varies geographically and between breeds. Our aim was to determine DEA 1 prevalence in a canine population in Luanda (Angola) and to assess alloimmunization risk after a mismatched blood transfusion. Blood samples were typed using an immunochromatographic strip technique. Of the 112 dogs tested (59 males; 53 females), 52.68% were DEA 1 positive and 47.32% DEA 1 negative. Females tended to be DEA 1 positive, and males DEA 1 negative (p = 0.0085). In a first-time mismatched blood transfusion, the calculated probability of a dog becoming sensitized was 24.9% and the probability of an acute hemolytic reaction following a second incompatible blood transfusion was 6.21%. DEA 1 prevalence obtained was similar to that reported worldwide, but differs from other African countries. The risk of alloimmunization and acute hemolytic transfusion reactions in mismatched blood transfusions is higher than that in other African regions. Blood typing is recommended prior to transfusion. Full article
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