Symmetry in Biosensors

A special issue of Symmetry (ISSN 2073-8994). This special issue belongs to the section "Engineering and Materials".

Deadline for manuscript submissions: 30 June 2026 | Viewed by 665

Special Issue Editor


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Guest Editor
Key Laboratory of Optoelectronic Technology and System of Ministry of Education, College of Optoelectronic Engineering, Chongqing University, Chongqing 400044, China
Interests: biophotoelectric sensing; precision testing and metrology; biophotonics
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Special Issue Information

Dear Colleagues,

We are pleased to announce a new Special Issue collection of the journal Symmetry entitled “Symmetry in Biosensors”.

Significant progress has been achieved in the field of bio-photoelectric sensing with the development of a sophisticated sensing platform that utilizes microsensors. This area of research focuses on exploring novel biosensing techniques designed for early disease detection, ensuring food safety, and monitoring environmental conditions. A notable breakthrough includes the development of a rapid liquid biopsy method that simplifies the processes of biomarker separation, enrichment, and identification in trace samples, reducing the procedure to just two minutes. The remarkable sensitivity of these detection capabilities has drastically improved the precision and effectiveness of cancer diagnostics and food safety evaluations.

This Special Issue aims to investigate how symmetry principles can enhance the sensitivity, accuracy, and reliability of biosensors in detecting biomarkers, particularly in the realms of cancer diagnostics and food safety. Topics within this Special Issue cover bio-photoelectric sensing, microsensors, trace detection techniques, liquid biopsy methods, biomarker research, and advancements in technologies related to cancer diagnostics and food safety. By highlighting the role of symmetry in biosensors, this Special Issue strives to propel advancements in the field of biosensing and pave the way for innovative solutions in healthcare and environmental monitoring. In this Special Issue, original research articles and reviews are welcome.

I look forward to receiving your contributions.

Prof. Dr. XiaoGang Lin
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Symmetry is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • bio-photoelectric sensing
  • microsensors
  • trace detection
  • liquid biopsy
  • biomarker research
  • cancer diagnostics
  • food safety

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Published Papers (1 paper)

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Review

24 pages, 7681 KB  
Review
Research Progress on Molecularly Imprinted Polymer-Aptasensors for Food Safety Detection
by Jiuyi Wang, Xiaogang Lin, Jinyu Wu, Xiao Lv, Binji Dai, Ke Wang and Jayne Wu
Symmetry 2025, 17(11), 1933; https://doi.org/10.3390/sym17111933 - 11 Nov 2025
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Abstract
The biological accumulation of microcontaminants and associated antibiotic resistance in food poses significant threats to both human and environmental health. Therefore, it is particularly crucial to design and develop methods of efficient identification and detection. Recently, molecularly imprinted polymers (MIPs) and aptamers (Apts), [...] Read more.
The biological accumulation of microcontaminants and associated antibiotic resistance in food poses significant threats to both human and environmental health. Therefore, it is particularly crucial to design and develop methods of efficient identification and detection. Recently, molecularly imprinted polymers (MIPs) and aptamers (Apts), as novel hybrid recognition elements, have received widespread attention from researchers. Because the dual recognition-based sensors have demonstrated enhanced performance and desirable characteristics, including high sensitivity, strong binding affinity, a low detection limit, and excellent stability under harsh environmental conditions, which are expected to be applied in food safety fields. This paper compares the characteristics of MIP and Apt, highlighting the significant advantages of molecularly imprinted polymer–aptamer (MIP-Apt) dual recognition in selectivity, sensitivity, and stability, which stems from their symmetric integration, akin to an extension of the ‘lock-and-key’ model. It then systematically discusses three synthetic strategies for MIP-Apt hybrid recognition systems and their applications for food safety detection, focusing on analyzing their detection strategies, sensing mechanisms, construction methodologies, performance evaluations, and potential application value. It also offers substantive perspectives on both the prevailing limitations and promising developmental pathways for MIP-Apt hybrid recognition-based sensing platforms. Full article
(This article belongs to the Special Issue Symmetry in Biosensors)
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