Special Issue "Comprehensive Multidimensional Gas Chromatography"

A special issue of Separations (ISSN 2297-8739).

Deadline for manuscript submissions: 30 June 2019

Special Issue Editors

Guest Editor
Dr. Katelynn A. Perrault

Laboratory of Forensic and Bioanalytical Chemistry, Division of Natural Sciences and Mathematics, Chaminade University of Honolulu, Honolulu HI 96815, USA
Website | E-Mail
Interests: forensic science, separation science and chromatography, decomposition chemistry, GC-MS
Guest Editor
Dr. Pierre-Hugues Stefanuto

Organic and Biological Analytical Chemistry Laboratory, University of Liège, Liège 4000, Belgium
Website | E-Mail
Interests: analytical chemistry, GCxGC, mass spectrometry, sample preparation

Special Issue Information

Dear Colleagues,

The next generation of cutting-edge separation technology is built on the concept of multidimensional systems. Recent developments in comprehensive two-dimensional gas chromatography (GC×GC) have caused the increased adoption of the technique across the analytical sciences and its extended applications across many “omics” fields. Software improvements, increased compatibility with a wider range of detectors, and the increased availability of commercial options have all contributed to a change in the landscape of GC×GC research and industry standards. However, a number of challenges remain in the field, including the standardization of data processing strategies, dealing with the high dimensionality of datasets using statistics, minimizing software bottlenecks, etc. Current fundamental developments in column and modulation technologies, as well as in prediction and data processing software, are essential to make it available to all potential users.

This Special Issue is intended to highlight advancements in the use of GC×GC and stimulate dialogue about major obstacles that are still preventing widespread adoption of GC×GC in relevant disciplines. Articles highlighting basic principles of GC×GC for new users are encouraged, in addition to new and emerging applications. Fundamental work on new developments, such as sample introduction, modulation, column technology, detector coupling, chemometrics, and others are also encouraged. This Special Issue is also an opportunity to highlight work presented during the 10th Multidimensional Chromatography Workshop, organized in Liège, Belgium (www.multidimensionalchromatography.com).

Dr. Katelynn A. Perrault
Dr. Pierre-Hugues Stefanuto
Guest Editors
Chairs of the 10th Multidimensional Chromatography Workshop

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Separations is an international peer-reviewed open access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 350 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • multidimensional chromateography
  • GCxGC
  • mass spectrometry
  • complex sample characterization
  • chemometrics
  • data processing
  • column technology
  • modulation
  • hyphenated systems
  • orthogonality
  • comprehensive chromatography

Published Papers

This special issue is now open for submission.
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