Innovative Adsorption Materials and Extraction Technology for Food Sample Detection

A special issue of Separations (ISSN 2297-8739).

Deadline for manuscript submissions: 20 December 2025 | Viewed by 1652

Special Issue Editors


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Guest Editor
College of Food Science and Engineering, Ningbo University, Ningbo, China
Interests: sample preparation; food safety; solid phase microextraction; nanomaterials; GC-MS; LC-MS; analytical methods

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Guest Editor
Institute of Agro-Product Safety and Nutrition, Zhejiang Academy of Agricultural Sciences, Hangzhou, China
Interests: sample preparation; food safety; nanomaterials; chemical hazardous
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Special Issue Information

Dear Colleagues,

This Issue seeks to address pressing challenges in food sample detection by advancing cutting-edge methodologies for the extraction and analysis of bioactive and hazardous components in food. With growing global concerns over food contamination, adulteration, and the demand for "farm-to-table" transparency, the development of efficient, sustainable, and selective extraction technologies has become paramount. Traditional methods often face limitations in selectivity, energy consumption, or scalability, necessitating innovations in adsorption materials and extraction techniques.

This Issue emphasizes the integration of material science, process engineering, and analytical chemistry to optimize the extraction of target compounds—such as allergens, pesticides, or mycotoxins—while minimizing co-extraction of interfering substances. Advanced analytical tools, including high-resolution chromatography, tandem mass spectrometry, and hyphenated spectroscopic techniques, are critical for validating extraction efficiency, ensuring extract purity, and enabling precise quantification of trace-level analytes. Furthermore, computational modeling and machine learning applications in process design will be highlighted to bridge experimental and theoretical advancements.

We invite contributions spanning original research, methodological innovations, and comprehensive reviews that explore novel materials, scalable technologies, or interdisciplinary strategies to enhance food safety protocols. Submissions addressing real-world applications, such as rapid on-site detection or industrial-scale implementation, are particularly encouraged.

Dr. Hangzhen Lan
Prof. Dr. Peipei Qi
Guest Editors

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Keywords

  • food
  • sample preparation
  • selective extraction
  • chromatography
  • mass spectrometry
  • computational modeling
  • machine learning

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Published Papers (2 papers)

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Research

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13 pages, 1406 KB  
Article
A Comprehensive Analytical Workflow for the Quantification of Carotenoid Presence in Chicken Egg Yolks
by Eleni D. Myrtsi, Dionysios T. Pavlopoulos, Vasilios Iliopoulos, Sofia D. Koulocheri and Serkos A. Haroutounian
Separations 2025, 12(11), 317; https://doi.org/10.3390/separations12110317 - 14 Nov 2025
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Abstract
Chicken egg is included among the main components of the human diet as an important source of nutrients, such as proteins, lipids, vitamins, minerals and carotenoids. The latter are terpenoid pigments present in egg yolks, providing their color and playing a vital role [...] Read more.
Chicken egg is included among the main components of the human diet as an important source of nutrients, such as proteins, lipids, vitamins, minerals and carotenoids. The latter are terpenoid pigments present in egg yolks, providing their color and playing a vital role because of their significant bioactivities. The carotenoid content of egg yolk varies considerably since it is strongly influenced by the respective laying hens’ farming and feeding procedures, and there is therefore a need to establish an efficient method for their assessment. The absence of such a method prompted us to develop a novel procedure consisting of the extraction, saponification and quantitative assessment of contained carotenoids. For this purpose, the optimal conditions for the extraction of carotenoids from egg yolks were defined, along with the optimal saponification conditions of carotenoids, with respect to reaction duration and pH influence on the extract’s contents of lutein and zeaxanthin. The carotenoid content of extracts was determined using a novel, developed herein LC-MS/MS method that allows the accurate, fast and simultaneous quantitation of the 11 most abundant carotenoids in egg yolks. The method accuracy and reliability were validated for six different parameters determined for each analyte. The novel procedure was applied for the assessment of the carotenoid content of ten egg yolks of diverse origin, indicating the bioactive carotenoids lutein and retinol as the most abundant, while lesser amounts of the remaining natural and synthetic carotenoids were found and there was no trace of fucoxanthin or astaxanthin molecules. The results herein revealed a variation in the carotenoid content of chicken eggs that depended on the diet and farming method of egg-laying hens. Full article
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Review

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47 pages, 15185 KB  
Review
Advances in Miniaturized Liquid Chromatography for the Detection of Organic Pollutants in Food, Environmental, and Biological Samples
by Kaoma Temwani, Daodong Pan, Zhen Wu, Yan Zhang and Hangzhen Lan
Separations 2025, 12(11), 312; https://doi.org/10.3390/separations12110312 - 11 Nov 2025
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Abstract
The advancement of miniaturized liquid chromatography (M-LC) systems has drawn considerable attention for their ability to enhance sensitivity, expedite analysis, and minimize the environmental impact of chemical usage in various analytical processes. This review explores the fundamental principles and recent innovations in M-LC [...] Read more.
The advancement of miniaturized liquid chromatography (M-LC) systems has drawn considerable attention for their ability to enhance sensitivity, expedite analysis, and minimize the environmental impact of chemical usage in various analytical processes. This review explores the fundamental principles and recent innovations in M-LC technology, including diverse pump designs, advanced column techniques, and the reduction in connection devices. Emphasizing the need for components that operate efficiently at the capillary or nanoscale with minimal dead volumes, we also discuss the development of benchtop instruments and mass spectrometry integrations. The review further highlights the growing applications of M-LC in food, environmental, and biological analyses, highlighting its potential as a powerful and emerging tool in separation science. Looking forward, addressing problems such as limited robustness, fabrication complexity, and integration with sensitive detectors will be instrumental to advancing M-LC technology. Modern innovation in microfabrication, materials science, and hyphenated methods holds great promise for allowing real-time, high-throughput, and portable analytical solutions in the near future. Full article
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