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Advances in Fluorescence and Raman Spectroscopy Techniques

A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Nanosensors".

Deadline for manuscript submissions: closed (30 November 2024) | Viewed by 2762

Special Issue Editor


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Guest Editor
Department of Physics & Astronomy, San Francisco State University, San Francisco, CA, USA
Interests: plasmonic; nanowire; fluorescence spectroscopy

Special Issue Information

Dear Colleagues,

Thanks to advances in computing technology (affordable and powerful hardware and software), laser technology and nanotechnology (leading to the invention of novel biomarkers, sensors, etc.), many exciting developments in fluorescence and Raman spectroscopy techniques have been achieved in the recent decades. These developments have opened novel ways for interrogating systems in life and physical sciences at single-molecule sensitivity and subnanometer resolution, evident from examples such as the invention of the super-resolution fluorescence microscopy technique. Such advanced imaging and spectroscopy techniques have found applications in biomedicine (e.g., the study of disease mechanisms at the molecular level and disease diagnostics in clinical settings), environmental sensing and information technology. This Special Issue aims to provide a venue for researchers to share their work and continued efforts towards the advancement of optical microscopy and spectroscopy techniques, with the hopes of finding novel applications for such techniques.

Original research and review articles for this Special Issue can include, but are not limited to:

  • Laser sources and detectors for advanced fluorescence and Raman spectroscopy techniques;
  • The simulation, design and fabrication of novel sensors and biomarkers with improved efficiency;
  • Algorithms and methods for data processing and analysis;
  • Nanomaterials and optical nanostructures for improved resolution and sensitivity, including simulation, design, synthesis, growth and fabrication technologies;
  • The application of advanced optical spectroscopy techniques in biomedicine, environmental sciences and information technology.

Dr. Huizhong Xu
Guest Editor

Manuscript Submission Information

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Keywords

  • bioimaging
  • biomarkers
  • biophotonics
  • fluorescence correlation spectroscopy
  • nanomaterials
  • nanoscopic spectroscopy
  • nano-optics
  • optical nanostructures
  • plasmonic nanostructures
  • single-molecule spectroscopy
  • super-resolution microscopy
  • surface-enhanced Raman spectroscopy (SERS)
  • tip-enhanced Raman spectroscopy (TERS)

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Published Papers (1 paper)

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Research

10 pages, 1579 KiB  
Communication
Characterizing Conformational Change of a Thermoresponsive Polymeric Nanoparticle with Raman Spectroscopy
by Luis Trabucco, Savannah Heath, Jonathan Shaw, Sean McFadden, Xiaodu Wang and Jing Yong Ye
Sensors 2023, 23(12), 5713; https://doi.org/10.3390/s23125713 - 19 Jun 2023
Cited by 2 | Viewed by 1815
Abstract
Molecular conformational changes in the collapsing and reswelling processes occurring during the phase transition at the lower critical solution temperature (LCST) of the polymer are not well understood. In this study, we characterized the conformational change of Poly(oligo(Ethylene Glycol) Methyl Ether Methacrylate)-144 (POEGMA-144) [...] Read more.
Molecular conformational changes in the collapsing and reswelling processes occurring during the phase transition at the lower critical solution temperature (LCST) of the polymer are not well understood. In this study, we characterized the conformational change of Poly(oligo(Ethylene Glycol) Methyl Ether Methacrylate)-144 (POEGMA-144) synthesized on silica nanoparticles using Raman spectroscopy and zeta potential measurements. Changes in distinct Raman peaks associated with the oligo(Ethylene Glycol) (OEG) side chains (1023, 1320, and 1499 cm−1) with respect to the methyl methacrylate (MMA) backbone (1608 cm−1) were observed and investigated under increasing and decreasing temperature profiles (34 °C to 50 °C) to evaluate the polymer collapse and reswelling around its LCST (42 °C). In contrast to the zeta potential measurements that monitor the change in surface charges as a whole during the phase transition, Raman spectroscopy provided more detailed information on vibrational modes of individual molecular moieties of the polymer in responding to the conformational change. Full article
(This article belongs to the Special Issue Advances in Fluorescence and Raman Spectroscopy Techniques)
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