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Approximately 50% of all cancer patients receive ionizing radiation therapy (RT) that contributes towards curative treatment in around 40% of cases. Despite improvements in target delineation, radiation techniques and dose fractionation and local and distant recurrences can occur, determining tre...

We publish high-quality Research Article and Reviews including basic, translational, clinical studies on the use of radiations for medical imaging including the following fields:

• radiology
• nuclear medicine
• dosimetry
• radiation protection
• radiopharmacy
• radiochemistry
• radiobiology
• radiation physics

Ionizing radiation induces a variety of lesions in DNA, of which double-strand breaks (DSBs) are considered the most lethal. Following irradiation, a multicomponent of signal transduction network referred as DNA damage response (DDR) is activated to sense DNA damages,...