Digital and 3D-Printed Dental Appliances: Materials, Design, and Clinical Applications

A special issue of Prosthesis (ISSN 2673-1592). This special issue belongs to the section "Prosthodontics".

Deadline for manuscript submissions: 31 December 2026 | Viewed by 2228

Editors


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Guest Editor
Department of Orthodontics, School of Dental Medicine, University of Zagreb, 10000 Zagreb, Croatia
Interests: digital orthodontics; 3D-printed orthodontic aligners; additively manufactured orthodontic devices; dental materials; CAD/CAM workflows; biomechanical performance of dental appliances; clinical evaluation of digitally fabricated orthodontic systems

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Guest Editor
Department of Prosthodontics, School of Dental Medicine, University of Zagreb, 10000 Zagreb, Croatia
Interests: digital prosthodontics; 3D-printed removable and fixed dental prostheses; additive manufacturing in prosthetic dentistry; CAD/CAM design of prosthetic restorations; materials and accuracy of 3D-printed prostheses; clinical performance of digitally fabricated prosthetic devices
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The rapid advancement of digital technologies has profoundly transformed contemporary prosthodontic and orthodontic practice. In particular, additive manufacturing has emerged as a key enabling technology for the fabrication of patient-specific dental appliances, allowing unprecedented control over design, material distribution, and manufacturing precision. The increasing clinical adoption of 3D-printed removable and fixed prostheses, orthodontic aligners, and adjunctive orthodontic devices reflects both technological maturity and a growing body of supporting scientific evidence. Nevertheless, significant challenges remain with regard to material performance, manufacturing accuracy, biomechanical behavior, and long-term clinical outcomes.

The primary aim of this Special Issue is to provide a comprehensive and critical overview of current research on 3D-printed dental appliances within the domains of prosthodontics and orthodontics. The scope of the Special Issue aligns closely with that of the journal Prosthesis by focusing on digitally fabricated prosthetic solutions, while also acknowledging the expanding role of orthodontic devices as integral components of modern digital prosthetic workflows. By addressing both disciplines within a unified framework, this Special Issue seeks to foster interdisciplinary dialogue and advance evidence-based digital dental care.

This Special Issue invites high-quality original research articles and authoritative review papers addressing fundamental and applied aspects of additive manufacturing in dentistry. Contributions are encouraged that examine digital design strategies, material properties, manufacturing accuracy, post-processing protocols, and clinical performance of 3D-printed prosthetic and orthodontic appliances. Particular emphasis is placed on removable and fixed prosthodontic restorations, 3D-printed orthodontic aligners, and digitally manufactured orthodontic devices, as well as their mechanical, biological, and biomechanical behavior. Studies reporting in vitro, in vivo, and clinical investigations, as well as systematic and narrative reviews synthesizing current evidence, are especially welcome.

In this Special Issue, original research articles and reviews are welcome. Research areas may include (but are not limited to) the following:

  • Additive manufacturing technologies in prosthetic and orthodontic dentistry.
  • 3D-printed removable and fixed prosthodontic restorations.
  • Digitally fabricated orthodontic aligners and orthodontic devices.
  • Dental materials for additive manufacturing.
  • The accuracy, fit, and dimensional stability of printed dental appliances.
  • CAD/CAM workflows and digital design strategies.
  • The mechanical and biomechanical performance of 3D-printed devices.
  • The clinical outcomes and long-term performance of digitally fabricated appliances.

We look forward to receiving your valuable contributions.

Dr. Luka Šimunović
Prof. Dr. Samir Čimić
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Prosthesis is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • three-dimensional printing
  • additive manufacturing
  • prosthodontics
  • orthodontic devices
  • digital dentistry
  • dental materials
  • CAD/CAM

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Published Papers (2 papers)

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12 pages, 3886 KB  
Case Report
Full-Arch Rehabilitation of an Edentulous Mandible with a Subperiosteal Implant Following Oncologic Reconstruction: A Case Report
by Justine Sanslaville Andres, Pauline Dussueil, Nicolas Lamy, Ramzi Ouadah and Hervé Moizan
Prosthesis 2026, 8(5), 47; https://doi.org/10.3390/prosthesis8050047 - 15 May 2026
Viewed by 672
Abstract
Background: Rehabilitation of edentulous mandibles in a post-oncologic setting remains a major clinical challenge. In such situations, placement of conventional endosseous implants may be compromised by severe bone deficiency, a history of peri-implant infection, and constraints related to reconstructive soft tissues. Customized [...] Read more.
Background: Rehabilitation of edentulous mandibles in a post-oncologic setting remains a major clinical challenge. In such situations, placement of conventional endosseous implants may be compromised by severe bone deficiency, a history of peri-implant infection, and constraints related to reconstructive soft tissues. Customized titanium subperiosteal implants, made possible by three-dimensional imaging, computer-aided design, and additive manufacturing, represent a potential alternative when conventional options are unfavorable. This case report describes a full-arch fixed rehabilitation of an edentulous mandible in a patient previously treated for squamous cell carcinoma of the floor of the mouth. Methods: A patient-specific titanium additively manufactured subperiosteal jaw implant (AMSJI) made of biocompatible titanium was designed using a digital planning workflow. Implant placement was performed in a single surgical session under general anesthesia, with fixation using osteosynthesis screws. A screw-retained full-arch provisional prosthesis was delivered intraoperatively, allowing immediate loading with adjustments aimed at avoiding compression of the healing soft tissues. Results: The patient achieved satisfactory functional and esthetic rehabilitation. Postoperative follow-up showed overall favorable mucosal tolerance; an early, limited peri-abutment mucosal dehiscence was observed and managed with suturing under local anesthesia, without compromising implant stability. Conclusions: This case highlights the clinical interest of patient-specific titanium subperiosteal implants as a fixed rehabilitation option in post-oncologic patients with major osseous and mucosal constraints and a history of reconstructive procedures. The combination of accurate digital planning and custom-made manufacturing may avoid the need for extensive bone grafting. However, these findings should be interpreted with caution due to the short-term follow-up and the inherent limitations of a single-case report, which limit the level of evidence and generalizability. Full article
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15 pages, 1951 KB  
Case Report
Minimally Invasive Rehabilitation of a Missing Maxillary Lateral Incisor Using a Lithium Disilicate Cantilever Resin-Bonded Prosthesis: A Clinical Case Report
by Mohanned M. Toras, Ossama Raffa, Hanaa Ashkar, Faris Alsufi and Loai Alsofi
Prosthesis 2026, 8(2), 17; https://doi.org/10.3390/prosthesis8020017 - 17 Feb 2026
Viewed by 1083
Abstract
This case report describes the esthetic and functional rehabilitation of a 45-year-old male patient presenting with a missing maxillary right lateral incisor (#12). Due to persistent insufficiency of alveolar ridge width following multiple augmentation procedures, implant placement was contraindicated. A minimally invasive prosthetic [...] Read more.
This case report describes the esthetic and functional rehabilitation of a 45-year-old male patient presenting with a missing maxillary right lateral incisor (#12). Due to persistent insufficiency of alveolar ridge width following multiple augmentation procedures, implant placement was contraindicated. A minimally invasive prosthetic approach was therefore selected, consisting of a single-retainer lithium disilicate resin-bonded fixed dental prosthesis (RBFDP) combined with laminate veneers to optimize anterior esthetics. The cantilever design and adhesive protocol were selected based on biomechanical principles aimed at minimizing interfacial stresses and preserving enamel structure. The prosthesis was fabricated using a fully digital workflow, and adhesive bonding was performed following established ceramic and enamel surface conditioning protocols. The restoration fulfilled the patient’s esthetic and functional expectations, and clinical follow-up at 18 months demonstrated stable bonding, healthy peri-abutment tissues, and absence of technical or biological complications. This case highlights the role of lithium disilicate cantilever RBFDPs as a minimally invasive and clinically viable treatment option for the replacement of maxillary lateral incisors when implant therapy is contraindicated, with outcomes limited to short- to medium-term observation. Full article
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