Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
2.6
2.1
Journals
Photonics
Special Issues
Optical Technologies for Biomedical Science
share announcement

Optical Technologies for Biomedical Science

A special issue of Photonics (ISSN 2304-6732). This special issue belongs to the section "Biophotonics and Biomedical Optics".

Deadline for manuscript submissions: 30 May 2025 | Viewed by 4988

Special Issue Editor

Dr. Geer Teng

E-Mail Website
Guest Editor
Department of Engineering Science, Institute of Biomedical Engineering, University of Oxford, Oxford OX3 7LD, UK
Interests: laser-induced breakdown spectroscopy; hyperspectral imaging; cancer diagnosis; clinical and biofilm samples monitoring; Raman spectroscopy; photoacoustic spectroscopy

Special Issue Information

Dear Colleagues,

In recent years, an increasing number of optical techniques have been applied in the field of biomedicine, playing a significant role in both diagnosis and treatment. Traditional medical diagnosis and treatment with drugs are facing many disadvantages such as damage and weak timeliness. Therefore, non-destructive detection technology and drug-free treatment auxiliary schemes will be one of the main development trends in the future.

Spectroscopy methods like Raman spectroscopy, laser-induced breakdown spectroscopy (LIBS), and fluorescence bring the chemical composition directly into the diagnosis. Microscopy, super-resolution techniques, hyperspectral imaging, and polarized optics provide more detailed space and spectral information. Optical technology has opened up new perspectives for biomedical applications, offering a fresh approach that is gradually transitioning from the laboratory to clinical practice, leading to a transformation in the field of biomedicine.

Given your expertise and significant contributions to the field, we are particularly interested in receiving a manuscript from you on your latest research findings or a review article highlighting the recent advancements in the application of optical techniques in biomedical research. We believe that your work would greatly benefit our readership and make a valuable addition to the scientific literature.

In this Special Issue, original research articles and reviews are welcome. Research areas may include (but are not limited to) the following:

  • Optics and spectroscopy in biomedical analysis;
  • Optical diagnosis (cancer, other diseases, clinical samples, etc.);
  • Multimodal imaging;
  • Molecular imaging and therapies;
  • Optical biophysics;
  • Nanophotonic biosensing;
  • Pharmaceutical analysis;
  • Non-destructive detection.

I/We look forward to receiving your contributions.

Dr. Geer Teng
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Photonics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • optics and spectroscopy in biomedical analysis
  • optical diagnosis (cancer, other diseases, clinical samples, etc.)
  • multimodal imaging
  • molecular imaging and therapies
  • optical biophysics
  • nanophotonic biosensing
  • pharmaceutical analysis
  • non-destructive detection

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.

Further information on MDPI's Special Issue policies can be found here.

Published Papers (4 papers)

Download All Papers
Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Research

11 pages, 4907 KiB  
Article
The Correction Method for Wavefront Aberration Caused by Spectrum-Splitting Filters in Multi-Modal Optical Imaging System
by Xiaolin Liu, Ying Huang, Xu Yan, Li Wang, Qiang Li, Tingcheng Zhang, Bin Hu, Wenping Lei, Shengbo Mu and Xiaohong Zhang
Photonics 2024, 11(9), 876; https://doi.org/10.3390/photonics11090876 - 19 Sep 2024
Cited by 1 | Viewed by 1021
Abstract
In current biomedical and environmental detection, multi-modal optical imaging technology is playing an increasingly important role. By utilizing information from dimensions such as spectra and polarization, it reflects the detailed characteristics and material properties of the targets. However, as detection system performance becomes [...] Read more.
In current biomedical and environmental detection, multi-modal optical imaging technology is playing an increasingly important role. By utilizing information from dimensions such as spectra and polarization, it reflects the detailed characteristics and material properties of the targets. However, as detection system performance becomes more complex, issues such as aberrations introduced by multilayered lenses, signal attenuation, decreased polarization sensitivity, and latency can no longer be ignored. These factors directly affect the assessment of image details, influencing subsequent analyses. In this paper, we propose a method for designing and optimizing spectrum-splitting filters that considers the wavefront aberration and transmittance of the multi-modal optical imaging system. The method of optimizing coating phases to minimize scalar phase aberrations while maximizing system transmission leads to substantially improved imaging performance. Simulation and experimental results demonstrate that the method can improve the imaging performance. The proposed approach has potential applications in fields such as biomedical field, multi-spectral, remote sensing and microscopy. Full article
(This article belongs to the Special Issue Optical Technologies for Biomedical Science)
►▼ Show Figures

Figure 1

18 pages, 4978 KiB  
Article
Detection of Abnormal Blood Flow Region Based on Near Infrared Correlation Spectroscopy
by Huiyan Hao, Wenyu Liu and Xulin Yu
Photonics 2024, 11(9), 798; https://doi.org/10.3390/photonics11090798 - 27 Aug 2024
Viewed by 688
Abstract
Blood flow measurement of microvessels in human tissues is of vital importance for the diagnosis and treatment of many diseases. In this paper, the detection method of abnormal blood flow regions based on near-infrared correlation spectroscopy is studied. We used the NL-Bregman-TV imaging [...] Read more.
Blood flow measurement of microvessels in human tissues is of vital importance for the diagnosis and treatment of many diseases. In this paper, the detection method of abnormal blood flow regions based on near-infrared correlation spectroscopy is studied. We used the NL-Bregman-TV imaging algorithm to realize Blood flow imaging. However, due to the limitation of the number and distribution of detectors, the pixels obtained from images are extremely low, which cannot meet the practical requirements of the visual and the abnormal blood flow range measurement. In this paper, the bicubic interpolation method is used to improve the resolution of low-pixel blood flow images. The parameter index of the normalized similarity was proposed to help judge the effect of the interpolation method on the resolution of this kind of image. Aiming at the extraction of abnormal regions, a threshold segmentation algorithm based on the histogram difference method and a morphological processing algorithm is proposed to extract the contour of abnormal blood flow. The method proposed in this paper can be used to accurately locate and extract the clear and smooth contour of abnormal blood flow. Full article
(This article belongs to the Special Issue Optical Technologies for Biomedical Science)
►▼ Show Figures

Figure 1

15 pages, 3068 KiB  
Article
Illuminating Life Sciences: A Biophysical Guide to the Use of Chromatic and White Light Sources in Photobiology
by Mira Mutschlechner and Harald Schöbel
Photonics 2024, 11(6), 487; https://doi.org/10.3390/photonics11060487 - 21 May 2024
Cited by 1 | Viewed by 962
Abstract
With the increasing availability of LEDs, researchers in photobiology have easier access to customized light sources. However, the abundance of different light sources poses new challenges for the correct characterization of existing light conditions. The photobiological effect of a light source depends mainly [...] Read more.
With the increasing availability of LEDs, researchers in photobiology have easier access to customized light sources. However, the abundance of different light sources poses new challenges for the correct characterization of existing light conditions. The photobiological effect of a light source depends mainly on the number of photons involved and the spectral composition. However, light sources are mainly described by parameters such as radiant flux, dominant or peak wavelength, and correlated color temperature (CCT). Therefore, in this work, chromatic and white light sources were measured for their spectral composition, various characterization parameters were determined, and the resulting photon flux densities were calculated, focusing on dominant versus peak wavelength for chromatic LEDs and the CCT for white LEDs and fluorescent tubes. The use of the dominant wavelength is inappropriate as it is partly outside the actual spectral range. It was also shown that white light sources with the same CCT have significantly different spectral compositions and, therefore, may have different photobiological effects. The results of this work should serve as a basis for life scientists to better compare light sources, to correctly interpret existing parameters, and to describe light conditions in a standardized and comparable way. Full article
(This article belongs to the Special Issue Optical Technologies for Biomedical Science)
►▼ Show Figures

Figure 1

13 pages, 3274 KiB  
Article
An Optically Augmented Visual Aid for Individuals with Age-Related Macular Degeneration
by Nahed H. Solouma, Noura Negm, Hafsah Ahmad and Yusuf Gamal
Photonics 2024, 11(3), 245; https://doi.org/10.3390/photonics11030245 - 8 Mar 2024
Viewed by 1471
Abstract
Normal vision is a precious gift to mankind. Any vision defect or degradation is actually an intimidating problem for individuals and societies. Therefore, researchers are continually working to find effective solutions for vision disorders. In some retinal diseases such as Age-related Macular Degeneration [...] Read more.
Normal vision is a precious gift to mankind. Any vision defect or degradation is actually an intimidating problem for individuals and societies. Therefore, researchers are continually working to find effective solutions for vision disorders. In some retinal diseases such as Age-related Macular Degeneration (AMD), visual aids are required to improve vision ability and/or stop the progress of the disease. Recently, augmented vision techniques have been used to provide aid to people suffering from retinal impairment. However, in such techniques, the images of real scenes are electronically deformed to compensate for vision impairment. Therefore, the natural scene is displayed as an electronic image on glasses. Intuitively, it is annoying to the patient to see electronic rather than natural scenes. Moreover, these visual aids are bulky and produce electric fields that might be harmful with continuous use. In this work, a novel optical solution to provide a visual aid to patients with central vision loss has been proposed. The proposed optical solution deforms the wavefront of the scene to entirely fall on the healthy parts of the retina. This, in turn, conveys all scene information to the brain to be perceived by the patient. As it provides optical processing, the proposed solution overcomes all drawbacks of the electronic solutions. To prove the validity of the proposed solution, three lenses were designed, fabricated, and tested to visualize simple shapes, reading, and obtaining aid during walking and driving. Obtaining the expected results from these tests, they were tried by three volunteers to clinically prove the validity and feasibility of the proposed optical aid. The feedback from the three patients was promising since all of them could recognize some of the details they used to miss with at least one of the lenses. Full article
(This article belongs to the Special Issue Optical Technologies for Biomedical Science)
►▼ Show Figures

Figure 1

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-4
Back to TopTop