Advances in Nanoemulsion for Drug Delivery
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Drug Delivery and Controlled Release".
Deadline for manuscript submissions: 28 February 2026 | Viewed by 100
Special Issue Editors
Interests: long acting implan; amorphous solid dispersion; continuous manufacturing
Special Issue Information
Dear Colleagues,
Nanoemulsions are kinetically stable, isotropic dispersions of oil and water that are stabilized by surfactants; they typically exhibit droplet sizes of 20–200 nm. Their unique properties—such as their high surface area, optical transparency, and improved stability—make them an attractive platform for drug delivery by increasing the solubility of poorly water-soluble drugs, enhancing bioavailability, enabling controlled release, and improving targeting to specific tissues or cells. Furthermore, nanoemulsions have been engineered as multifunctional platforms for diagnostic and theranostic applications, advancing precision medicine. Despite significant progress being made in relation to formulation strategies, nanoemulsion-based delivery systems still face key challenges in stability, scalable manufacturing, efficient drug loading, controlled release, extrahepatic targeting, and concerns related to immunogenicity and toxicity.
This Special Issue aims to showcase recent cutting-edge research and technologies that advance the design, characterization, and application of novel nanoemulsion-based systems for drug delivery and disease diagnosis. We invite original research articles and reviews that deepen our understanding of fundamental principles, develop innovative technologies, and address translational challenges and clinical gaps from bench to bedside. In particular, topics of interest include (but are not limited to) the following:
- Formulation technologies for nanoemulsions, including novel emulsifiers, processing techniques, and scale-up approaches.
- Nano–bio interactions, including cellular uptake, biodistribution, immune response, and toxicity studies.
- Targeted delivery of small molecules, peptides, proteins, and nucleic acids.
- Nanoemulsion-based imaging and theranostic applications.
- Nanoemulsion-based adjuvants for vaccines and immunotherapies.
- Translational and clinical challenges, including regulatory considerations, safety, and manufacturing.
- Emerging applications in oncology, infectious diseases, pulmonary diseases, and beyond.
Dr. Feng Zhang
Dr. Qian Zhong
Guest Editors
Manuscript Submission Information
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Keywords
- nanoemulsion formulations and stability
- topical delivery
- poorly soluble drugs
- targeted drug and biologics delivery
- theranostic platform and imaging
- vaccines and adjuvants
- cancer
- infectious diseases
- pulmonary diseases
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