Micro- and Nanotechnology Empowering Combination Therapy of Cancer and Chronic Diseases

A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Nanomedicine and Nanotechnology".

Deadline for manuscript submissions: 31 December 2025 | Viewed by 45

Special Issue Editor


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Guest Editor
Precision Regenerative Medicine Research Center, Medical Science Division, Macau University of Science and Technology, Macau, China
Interests: nanotechnology; drug delivery; computer-aided design; nanomedicine; hydrogel; long-acting injectable; controlled drug release; combination therapy; bioavailability; biological barrier
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Special Issue Information

Dear Colleagues,

Combination therapy has shown significance in clinical practice for cancer and many chronic diseases due to its promise in outpacing the efficiency of any singular treatment method. The novel approach strategically amalgamates various treatment modalities, including but not limited to the synergistic combination of chemo-drugs and/or molecular therapy, the combination of small-molecule drugs such as antibiotics and steroids, the integration of immunotherapy into traditional chemotherapy, theranostics, and multicomponent natural medicine extract. Drug formulation is a critical aspect of pharmaceutical development to create viable drug products of combination therapy with desired properties. An optimized design and preparation of formulation/drug delivery system can meet the growth demand for safer and more effective combination treatment.

To adeptly address the complexity of disease heterogeneity and treatment resistance, this Special Issue highlights and captures the recent progress and contemporary landscape of combination therapy in various modalities/formulations/dosage forms empowered by the advent of micro- and nanotechnologies as well as supervised artificial intelligence. We are pleased to invite you to submit all types of pertinent articles, and topics of interest include (but are not limited to) drug delivery technologies/methods, design and characterization (e.g., drug release and excipient selection), therapeutic evaluations in cancer and chronic diseases, and novel treatment regimens.

Dr. Rui Xue Zhang
Guest Editor

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Keywords

  • nanotechnology
  • drug delivery
  • computer-aided design
  • nanomedicine
  • hydrogel
  • long-acting injectable
  • controlled drug release
  • combination therapy
  • bioavailability
  • biological barrier

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Published Papers

This special issue is now open for submission.
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