Advancing Drug Delivery Systems and Pharmaceutical Formulations

A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Drug Delivery and Controlled Release".

Deadline for manuscript submissions: 30 September 2026 | Viewed by 231

Editors


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Guest Editor
Department of Clinical Pharmacy, Lithuanian University of Health Sciences, Sukileliy Street 13, LT-50161 Kaunas, Lithuania
Interests: natural compounds; plant extract; analytical chemistry; pharmaceutical development; drug delivery
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Department of Drug Technology and Social Pharmacy, Lithuanian University of Health Sciences, LT-50161 Kaunas, Lithuania
Interests: natural ingredients; pharmaceutical forms; microencapsulation; 3D printing

Special Issue Information

Dear Colleagues,

Despite continuous advances in pharmaceutical sciences, the efficient delivery of active pharmaceutical ingredients to their intended sites of action remains a major challenge limiting therapeutic efficacy. Many drug candidates suffer from unfavorable physicochemical properties, such as poor aqueous solubility, limited permeability, chemical or physical instability and unpredictable pharmacokinetics. Consequently, the rational design of advanced drug delivery systems and pharmaceutical formulations has become a critical focus for improving drug performance, safety and patient outcomes.

Recent progress in formulation science has enabled the development of sophisticated delivery systems capable of enhancing drug bioavailability, protecting labile compounds from degradation, modulating release kinetics and enabling site-specific or stimuli-responsive delivery. These advances span a wide range of technologies, including particulate and nanoscale systems, lipid- and polymer-based carriers, amorphous and solid-state formulations, hybrid materials and advanced manufacturing and processing approaches. Equally important are improvements in formulation characterization, in vitro–in vivo correlation and predictive tools supporting rational formulation design.

This Special Issue aims to highlight cutting-edge research and comprehensive reviews addressing the development, characterization and performance of advanced drug delivery systems and pharmaceutical formulations. Contributions are welcome on formulation strategies, processing and manufacturing technologies, physicochemical and biopharmaceutical evaluation, as well as in vitro and in vivo studies elucidating drug transport, release, absorption and therapeutic efficacy. Studies emphasizing translational relevance, scalability, quality-by-design principles and regulatory considerations are particularly encouraged.

By integrating multidisciplinary perspectives, this Special Issue seeks to advance the fundamental and applied understanding of drug delivery science and to foster innovative formulation approaches that enable more effective, reliable and patient-centered therapies.

Prof. Dr. Kristina Ramanauskienė
Dr. Lauryna Pudžiuvelytė
Guest Editors

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceutics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • drug delivery systems
  • pharmaceutical formulations
  • active pharmaceutical ingredients
  • bioavailability
  • nanoscale systems
  • lipid-based carriers
  • polymer-based carriers
  • amorphous formulations
  • solid-state formulations
  • hybrid materials
  • controlled release
  • stimuli-responsive delivery
  • site-specific delivery
  • physicochemical characterization
  • biopharmaceutical evaluation
  • in vitro-in vivo correlation
  • translational research
  • quality-by-design
  • scalable manufacturing
  • therapeutic efficacy

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Published Papers

This special issue is now open for submission.
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