The Integration of Novel Approaches in Laboratory Medicine into Precision Pharmacotherapy
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Pharmacokinetics and Pharmacodynamics".
Deadline for manuscript submissions: 31 December 2025 | Viewed by 33
Special Issue Editor
Interests: therapeutic drug monitoring; pharmacokinetics; liquid chromatography; mass spectrometry
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
In the past few decades, laboratory medicine has evolved into a multidisciplinary field, with an abundance of various approaches having become available to support the screening, diagnosis, monitoring and prognostics of human diseases. The routine laboratory toolkit now comprises automated and special clinical chemistry, hematology, hemostasis, immunology, genetics and microbiology, and the integrated application of skills related to these disciplines is of increasing interest in clinical care. Relevant clinical areas include PK-PD-guided antibiotic treatment, biological therapies, organ transplant, targeted therapies in oncology, or the laboratory assessment of adverse drug effects. As a result, the pharmaceutical community is increasingly recognizing the importance of having skills related to laboratory and point-of-care investigations.
Bioinformatics is an essential tool used to integrate the results of laboratory assays into precision pharmacotherapy. Its importance is particularly prevalent in pharmacokinetic and pharmacodynamic analyses, omics, and the analysis of big datasets for identifying confounding biomarkers for diagnosing a pathological condition, as well as for revealing adverse drug effects. In addition, machine learning tools and artificial intelligence define new dimensions of processing laboratory data, and one of the most notable fields that can benefit from this revolution is pharmacotherapy.
The aim of this Special Issue is to widen the scope of precision pharmacotherapy by highlighting the application of state-of-the-art or novel multidisciplinary laboratory methodology integrated with contemporary bioinformatics to support decision making in clinical pharmacokinetics, clinical pharmacodynamics, and the management of drug administration. The Guest Editor hopes that the articles appearing in this Special Issue will contribute to the integration of knowledge pertaining to pharmaceutics and laboratory medicine for the benefit of patients.
Dr. Gellért Balázs Karvaly
Guest Editor
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Keywords
- therapeutic drug monitoring
- pharmacokinetics
- pharmacodynamics
- bioinformatics
- clinical chemistry
- mass spectrometry
- immunology
- clinical genetics
- antiinfectives
- artificial intelligence
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