Biomaterials-Based Drug Delivery Systems in Regenerative Medicine
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Drug Delivery and Controlled Release".
Deadline for manuscript submissions: 30 September 2025 | Viewed by 373
Special Issue Editor
Interests: tissue regeneration; photodynamic therapy; silk fibrin; biopolymer; polymeric scaffold
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Regenerative medicine and tissue engineering are at the forefront of healthcare innovation, offering solutions for tissue damage, organ failure, and degenerative diseases. Central to these fields is the development of advanced biomaterials, which provide critical scaffolding and therapeutic agents necessary for tissue regeneration.
Therapeutic approaches in regenerative medicine are increasingly incorporating advanced biomaterials with drug delivery systems to enhance the efficacy of treatments. These systems allow for the controlled release of therapeutic agents, such as growth factors, small molecule drugs, and nucleic acids, in a spatially and temporally precise manner. This precision is crucial for stimulating cellular processes like proliferation, differentiation, and migration, which are essential for tissue repair and regeneration.
Stem cell therapy, a cornerstone of regenerative medicine, benefits significantly from biomaterials and drug delivery systems. The combination of stem cells with biomimetic scaffolds and controlled release of differentiation factors can guide stem cell fate, improving the regenerative outcomes. Additionally, gene therapy, which enables genetic modifications to promote tissue repair, is further enhanced when delivered through biomaterials that protect genetic material and facilitate its uptake by target cells.
The integration of nanotechnology in biomaterials has led to the creation of nanostructured drug delivery systems. These nanofibers and nanoparticles not only improve the mechanical and biological properties of scaffolds but also provide large surface areas for drug loading and targeted delivery, thus improving the efficacy of regenerative treatments.
In this Special Issue of Pharmaceutics, we invite authors to submit original research articles or reviews that explore the intersection of biomaterials, drug delivery, and regenerative medicine. We are particularly interested in submissions that address the following topics:
- Innovations in tissue engineering approaches integrating drug delivery systems;
- The role of biomaterials in stem cell therapy and regenerative applications;
- Advanced drug delivery systems for regenerative medicine, including nanoscale delivery vehicles;
- The combination of gene therapy with biomaterials for enhanced tissue repair.
Prof. Dr. Rogério Leone Buchaim
Guest Editor
Manuscript Submission Information
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Keywords
- tissue regeneration
- drug delivery systems
- regenerative medicine
- biomaterials
- stem cell therapy
- gene therapy
- nanostructured biomaterials
- biomimetic materials
- decellularized extracellular matrices
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