Conferences

8–9 May 2019, Joseph B. Martin Conference Centre, Harvard Medical School, Boston, MA
Better leads, Better Drugs: Innovation in screening libraries

About the organisers:

ADDC is a not-for-profit organization of 149 Centres and 1878 members around the world. We host a national symposium every 12-18 month to cover topics of importance to drug discovery scientists from academia and industry.

Synopsis

Scientists engaged in drug discovery and chemical biology know that a screen is only as good as the molecules that go into it. But with the vast potential chemical space, how do you decide what to include in your virtual, high-throughput, or fragment-based screens? This event will bring together drug-seekers from academia and industry focused on the application of new technologies and computational tools to tackle this question to deliver higher quality leads.

This 1.5-day meeting will create a dynamic, interactive environment for presentations and discussion, and includes a ½-day networking session for one on one partnering meetings between participants and round table discussions on key topics: Sharing libraries among academics; Informatics including data management flow; Virtual screening software tools and open source software.

The full program is nearly complete and includes world-class lecturers from the National Chemical Genomics Center, University of California, San Francisco, and Northeastern University, as well as several biotech’s and pharmas.

We have a good set of speakers secured from industry and academia around a broad range of subjects:

DNA-encoded library: Diversity via Building blocks and scaffolds; Katelyn Billings, GlaxoSmithKline
From DEX Library Design to Preclinical Candidate: Case Study of the Discovery of X-165; Ying Zhang, X-Chem
Innovative chemical libraries to enable public sector drug repurposing, chemical biology, and novel medicinal chemistry; Ajit Jadav, NIH/NCATS
Discovery of novel chemistry for new biology from within a billion compounds you can buy in 6 weeks; John Irwin, UCSF Pharmaceutical Chemistry
Human kinase repurposing strategies for neglected tropical disease drug discovery; Lori Ferrins, Northeastern University
Designing, Curating and NMR Screening New Fragment Libraries for Discovering Small-molecule Drug Leads; Steven LaPlante, University of Quebec, Visiting professor at Broad Institute
Mechanism of action libraries in academic screening; Jeremy Jenkins, Novartis Institute of Biomedical Sciences
Targeted Protein Degradation as a Novel Therapeutic Approach; Stewart Fisher, C4 Therapeutics, Inc.
Biologically-informed focused libraries; Jerry Joyce, Director of the Genomics Institute of the Novartis Research Foundation (GNF)
Screening diverse libraries of constrained bicyclic peptides by phage display yields high quality hits for development of novel therapeutics; Kevin McDonnell, BicycleTx

Further details for the conference can be found on the events page:

https://bit.ly/2T57iHk

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