Microbial Mechanisms and Host Interactions in Oral Diseases: Implications for Pathogenesis, Prevention, and Novel Therapeutics
A special issue of Pathogens (ISSN 2076-0817).
Deadline for manuscript submissions: closed (15 December 2025) | Viewed by 668
Special Issue Editor
Interests: cancer immunotherapy; oral cancer; oral pathology; personalized medicine
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Oral diseases, including dental caries, periodontal diseases, and oral cancers, continue to pose a significant global health challenge. These conditions arise from a multifaceted interaction of genetic predispositions, environmental influences, and microbial factors, with poor oral hygiene and lifestyle practices playing pivotal roles.
This review delves into the etiology and pathogenesis of prevalent oral diseases, emphasizing the role of microbial biofilms, host immune responses, and their systemic health implications. It also explores advancements in diagnostic technologies, such as molecular assays and advanced imaging techniques, that have enhanced early detection and disease monitoring.
Preventive strategies, including the use of fluoride, dietary modifications, and large-scale public health initiatives, are critically evaluated. Additionally, the review highlights innovative therapeutic approaches—ranging from probiotics and nanotechnology to regenerative medicine—that hold promise for transforming oral healthcare practices.
A holistic understanding of oral diseases is imperative for developing effective prevention strategies, improving early detection, and achieving better treatment outcomes.
Prof. Dr. Shankargouda B. Patil
Guest Editor
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Keywords
- oral diseases
- dental caries
- periodontal disease
- microbial biofilms
- innovative therapeutics
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