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Pathogens
Special Issues
Insights into Fungal Infections
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Insights into Fungal Infections

A special issue of Pathogens (ISSN 2076-0817). This special issue belongs to the section "Fungal Pathogens".

Deadline for manuscript submissions: 30 April 2026 | Viewed by 658

Special Issue Editors

Dr. María del Rocío Reyes Montes

E-Mail Website
Guest Editor
Departamento de Microbiología-Parasitología, Facultad de Medicina, Universidad Nacional Autónoma de México (UNAM), Mexico City 04510, Mexico
Interests: molecular epidemiology; molecular diagnostic; molecular markers; aspergillosis; coccidioidomicosis; dermatophytosis
Special Issues, Collections and Topics in MDPI journals
Dr. Esperanza Duarte-Escalante

E-Mail Website
Guest Editor
Departamento de Microbiología-Parasitología, Facultad de Medicina, Universidad Nacional Autónoma de México (UNAM), Mexico City 04510, Mexico
Interests: molecular epidemiology; molecular diagnostic; molecular markers; aspergillosis; coccidioidomicosis; dermatophytosis
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

We are pleased to invite submissions to our Special Issue “Insights into Fungal Infections” in Pathogens (ISSN: 2076-0817).

In recent years, the landscape of fungal infections has been significantly transformed by advancing global interconnectedness, environmental changes, and evolving host susceptibility patterns. This Special Issue will explore the most innovative aspects of current mycological research, including host–pathogen interactions, molecular mechanisms of fungal pathogenesis, epidemiological surveillance, and the growing impact of climate change on fungal distribution and virulence.

As Guest Editors, we welcome original research articles, comprehensive reviews, systematic reviews, and clinical studies addressing novel diagnostic approaches, antifungal resistance mechanisms, and innovative therapeutic strategies, including the development of next-generation antifungals and immunomodulatory interventions. All accepted manuscripts will receive expedited processing and rigorous peer review.

Dr. María del Rocío Reyes Montes
Dr. Esperanza Duarte-Escalante
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pathogens is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • fungal infections
  • host–pathogen interaction
  • pathogenesis
  • epidemiology
  • climate change
  • diagnosis
  • treatment

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Further information on MDPI's Special Issue policies can be found here.

Published Papers (1 paper)

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Research

11 pages, 433 KB  
Article
Clinical and Microbiological Profile of Oral Candidiasis: A Retrospective Study
by Maja Ptasiewicz, Karolina Thum-Tyzo, Alicja Matejko, Julia Georges, Emanuela Bis, Aleksandra Strączek, Renata Chałas and Agnieszka Magryś
Pathogens 2026, 15(2), 195; https://doi.org/10.3390/pathogens15020195 - 10 Feb 2026
Viewed by 463
Abstract
Introduction: Oral candidiasis is a common opportunistic fungal infection of the oral mucosa, most frequently caused by Candida albicans. Its development is influenced by local factors, such as denture use and oral hygiene, as well as systemic conditions including diabetes, nutritional [...] Read more.
Introduction: Oral candidiasis is a common opportunistic fungal infection of the oral mucosa, most frequently caused by Candida albicans. Its development is influenced by local factors, such as denture use and oral hygiene, as well as systemic conditions including diabetes, nutritional deficiencies, and chronic inflammatory diseases. Accurate diagnosis requires both clinical evaluation and mycological testing. The aim of this retrospective study was to analyze demographic characteristics, predisposing factors, and the species distribution of Candida isolates in patients diagnosed with oral candidiasis. Materials and Methods: A retrospective review of medical documentation was conducted to evaluate patient demographics, risk factors, comorbidities, denture use, and results of mycological examinations confirming oral candidiasis. Results: A total of 71 patients (49 women and 22 men), aged 21–85 years (mean 59.6 ± 16 years), were included in the study. Fungal etiology was confirmed in all cases, with Candida albicans identified most frequently (81.69%). Among comorbidities, cardiovascular diseases were most common (30.99%), followed by diabetes (14.08%), and chronic periodontitis, respiratory, and gastrointestinal diseases (each 11.27%). Removable dentures were used by 18.30% of patients, and nicotine addiction was reported in 9.86%. All strains were susceptible to the tested antifungals, except for species with known intrinsic resistance. Conclusions: Oral candidiasis in this cohort predominantly affected women and older adults, with Candida albicans remaining the most common etiological agent. Denture use emerged as an important local predisposing factor and was associated with a higher proportion of infections caused by non-albicans species. These findings underscore the importance of comprehensive clinical evaluation and routine mycological testing to guide targeted antifungal therapy, especially in patients with risk factors such as denture use or systemic comorbidities. Full article
(This article belongs to the Special Issue Insights into Fungal Infections)
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