Innovations and Developments in the Diagnosis of Sexually Transmitted Diseases
A special issue of Pathogens (ISSN 2076-0817). This special issue belongs to the section "Viral Pathogens".
Deadline for manuscript submissions: closed (20 January 2024) | Viewed by 2396
Special Issue Editors
Interests: molecular epidemiology; next generation sequencing; bacterial virulence; Identification and characterization of novel antimicrobial compounds
Special Issue Information
Dear Colleagues,
Sexually transmitted infections (STIs), which have accompanied the human race since the dawn of history, still cause substantial human suffering. According to the World Health Organization, more than a million people are infected with STIs every day. Over thirty different pathogens are known to cause STI, including viruses, bacteria, and parasites. According to the 2016 World Health Organization report, 376 million people worldwide have been infected, including 127 million in chlamydia, 87 million in gonorrhea and 6.3 million in syphilis. These three pathogens alone account for about 60% of all STIs worldwide. There are worldwide alarming reports about the emergence of multi drug resistant Neisseria gonorrhoeae and experts fear from untreatable gonococcal infections. In addition, Mycoplasma genitalium is a bacterium that may cause STIs in both men and women. While it may express as urethritis or proctitis in men, it may cause cervicitis, infertility and other morbidities in women. This infection has become a main concern due to its development of antimicrobial resistance, specifically Macrolide and quinolones resistance, such as Azithromycin and moxifloxacin. Although it can be Asymptomatic, and despite the presumably high rates of antibiotic resistance in the population, treatment with Azithromycin, doxycicline or moxifloxacin are still suggested without a real proof of benefit. During the recent years, novel diagnostic methods were developed, some of them were already integrated into the routine lab work. Since it is not possible to encompass the breadth of venereal disease in a single volume, we decided to focus on innovation and developments in the field of diagnosis, methods that can help physicians to give a better treatments to their patients.
For this special issue we will welcome articles dealing with the various aspects of diagnosis of sexually transmitted diseases, including novel developments, validated tests, study results, the use of next generation sequencing (NGS) for diagnosis, determination of antimicrobial resistance and virulence, PCR, MALDI-TOF, serology and much more!
Both original research and review articles are welcome. Potential topics include, but are not limited to: diagnostics, PCR, NGS, MALDI-TOF, serology, antibiotic resistance, virulence gene and more.
Dr. Israel Nissan
Dr. Itzchak Levy
Guest Editors
Keywords
- sexually transmitted infections (STIs)
- Neisseria gonorrhea
- Chlamydia trachomatis
- Treponema pallidum
- Mycoplasma genitalium
- gonorrhea
- syphilis
- chlamydia
- molecular epidemiology
- diagnosis
- virulence factors
- pathogenesis
- pathophysiology
- transmission
- molecular epidemiology
