Salmonella and Campylobacter Infection in Poultry
A special issue of Pathogens (ISSN 2076-0817). This special issue belongs to the section "Bacterial Pathogens".
Deadline for manuscript submissions: closed (30 November 2021) | Viewed by 6074
Special Issue Editor
Special Issue Information
Dear Colleagues,
Members of the bacterial genera, Salmonella and Campylobacter, are among the leading causes of bacterial foodborne gastrointestinal disease in humans. Humans can acquire the bacteria from a number of sources, but eggs and poultry meat are commonly identified during traceback investigation. One of the major issues with these zoonotic bacteria is their ability to establish persistent infection within the intestinal tract of commercial poultry birds. Persistently infected birds can then shed the bacteria into the farm environment, which presents risks for the subsequent contamination of the downstream food supply chain for humans.
Upon infection with Salmonella and/or Campylobacter spp., poultry typically do not exhibit clinical signs of infection. This could be due to a number of factors, including initial dose and less reactive immune response. Stringent cleaning processes on farms using commercial sanitzers have been shown to reduce bacterial numbers in poultry sheds. Thus the initial exposure of birds to Salmonella and/or Campylobacter may be below the threshold required to cause disease or stimulate the host immune response. The toll-like recepter (TLR) 4 in poultry, for example, is known to have a reduced response to bacterial lipopolysacharride (LPS), compared with mammals.
Despite the use of vaccines as well as farm-to-fork control strategies, Salmonella spp. and Campylobacter spp. continue to represet a significant public health risk. The focus of this Special Issue will be on host–bacterial interaction in poultry birds with special interest on the mechanisms involved in Salmonella and Campylobacter persistence, as well as the host immune response to infection. The aim of this Special Issue is to highlight and expand our current understanding of host–pathogen interactions between Campylobacter, Salmonella in different commercial poultry birds.
Dr. Andrea McWhorter
Guest Editor
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Keywords
- Salmonella
- Campylobacter
- broilers
- layer hens
- virulence
- host–immune response
- tolerance
- host–pathogen interaction
- persistent infection
