Metabolism for Parasitism

Dear Colleagues,

Metabolism in parasites and the metabolic interplays between parasites and their hosts are important for the survival of parasites and the establishment of parasitism. Key molecules such as essential enzymes and regulators are also common targets in the development of antiparasitic therapeutics.

Here we call for original research articles reporting new findings, as well as review articles summarizing recent progresses, on the molecules involved in the metabolism in parasites or in their hosts in response to parasitic infections. Topics of interest include (but are not limited to):

1) Functional characterizations of individual enzymes, regulators or chaperones in the metabolic pathways in a parasite or host in response to infection at molecular, biochemical, cellular, and/or organismal levels.

2) Role of specified macromolecules or small molecules in parasite metabolism, survival, and/or parasite–host interactions.

3) Discovery and characterization of drug targets with target validation by genetic manipulation of the target.

4) Discovery and characterization of drug targets with nanomolar to micromolar levels of antiparasitic efficacy in vitro, preferably with efficacy data in vivo.

5) Characterizations of metabolic pathways in parasites and/or hosts in response to parasitic infections by functional genomics, proteomics, and/or metabolomics approaches, providing in-depth analysis of biological meanings, preferably with some experimental validation.

6) Comprehensive or concise reviews on any topics related to parasite metabolism suitable for students, investigators, or clinician scientists in the biomedical, veterinary, or medical fields.

Prof. Dr. Guan Zhu
Prof. Dr. Bang Shen
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pathogens is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.