Special Issue "Host-Microbe Interaction in Atopic Diseases"
A special issue of Pathogens (ISSN 2076-0817). This special issue belongs to the section "Immunological Responses and Immune Defense Mechanisms".
Deadline for manuscript submissions: closed (31 May 2022) | Viewed by 2874
Interests: asthma; innate immunity; mucosal immunology
Atopic diseases, such as asthma and atopic dermatitis, are severe multifactorial disorders characterized by distinct clinical and pathological features. Recent studies have highlighted the importance of exposure to pathogens in influencing host susceptibility to these diseases. While many studies have demonstrated the association between viral or bacterial infection and disease exacerbation, early childhood exposure to certain microbes can confer protection (hygiene hypothesis), particularly in the context of allergic asthma. A key factor that mediates these outcomes is the interaction between microbial products and the host immune system. However, many gaps in our knowledge remain to be filled before we can obtain a comprehensive understanding of how microbes shape the immune responses to a tolerant or inflammatory state. In this Special Issue, we aim to advance communication between microbiologists and immunologists and, as a result, knowledge at the interface of interactions between microbes and the host immune system. This Special Issue will focus on the impact of pathogens on the development of atopic diseases, particularly of the lungs and skin. Both original research and review articles are welcomed. Potential topics include, but are not limited to:
- Molecular mechanisms of asthma and airway hyperreactivity caused by respiratory infection;
- Role of microbiota in skin immunity and atopic dermatitis;
- Immunological mechanisms causing secondary infections in atopic dermatitis;
- Molecular interactions between microbial products and host immune responses;
- Innate responses to infections including cytokine and cellular responses and functions;
- Links between innate responses and downstream adaptive responses;
- Molecular signaling from sensors or receptors for microbial products or infection-induced changes, and from cytokines induced during infections.
Dr. Ya-Jen Chang
Dr. Christina Li-Ping Thio
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- respiratory pathogen
- microbial infection
- atopic dermatitis
- lung function
- airway hyperreactivity
- immune responses