Modeling Antifungal Host Defense to Impact Therapy and Management of Infections

A special issue of Pathogens (ISSN 2076-0817). This special issue belongs to the section "Fungal Pathogens".

Deadline for manuscript submissions: closed (31 May 2023) | Viewed by 557

Special Issue Editors


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Guest Editor
Leibniz Institute for Natural Product Research and Infection Biology - Hans Knöll Institute, Beutenbergstraße 11a, 07745, Jena, Germany
Interests: Immunology of fungal infections, Immune evasion, Immunotherapy, in vitro infection models, Candida albicans

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Guest Editor
South Texas Center for Emerging Infectious Diseases, The University of Texas at San Antonio, San Antonio, TX 78249, USA
Interests: medical mycology; innate immune responses; adaptive immune responses; pattern recognition receptors; vaccine development

Special Issue Information

The purpose of the Special Issue for the upcoming 2021 Gordon Research Seminar “Immunology of Fungal Infections” is to highlight cutting-edge research and new model systems that drive our field forward. The occurrence of fungal infections continues to rise and pose a serious threat to public health, yet this problem is under-appreciated despite having a similar impact to other clinically relevant infectious diseases such as malaria or tuberculosis.

Fungal infections range from superficial infections of the skin and mucosa that impact quality of life to life-threatening invasive infections. The majority of invasive infections are caused by Candida, Aspergillus, and Cryptococcus, however, with the rise of immunosuppressive therapy and increases in organ transplant therapy there is an increased incidence of diverse fungal species. Moreover, many deaths related to the novel coronavirus COVID-19 are believed to be attributable to fungal co-infections.

The Gordon Research Seminar on Immunology of Fungal Infections invites early-career medical mycologists to contribute to this Special Issue in Pathogens. This Issue will be devoted to presenting cutting-edge ideas, sharing novel insights in host–fungal pathogen interactions, presenting new discoveries in immune pathways that protect against fungal infections, and exploring how we can exploit this new knowledge to develop novel therapeutic and diagnostic strategies.

The GRS seminar allows for young investigators around the world to build future collaborations and interact with leading experts in fundamental biology as well as clinical research. 

Original research and review articles are welcomed. Topics of interest include but are not limited to:

  • Immunology of systemic fungal infections;
  • Mucosal immunology to fungal infections;
  • Innate and adaptive antifungal immunity;
  • Vaccine and therapeutic treatments for fungal infections;
  • Host–pathogen interactions;
  • Fungal pathogenesis;
  • Immune adaptation: adaptation of the pathogen to the immune response.

Dr. Mark S. Gresnigt
Dr. Althea Campuzano
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pathogens is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • medical mycology
  • host-pathogen interactions
  • signaling pathways
  • innate immunity, adaptive immunity
  • fungal vaccines
  • Aspergillus
  • Blastomycetes
  • Candida
  • Cryptococcus
  • Coccidioides
  • Histoplasma
  • Mucorales
  • yeasts
  • molds
  • immunotherapy

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Published Papers

There is no accepted submissions to this special issue at this moment.
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