Toxoplasmosis in Immunocompromised and Immunocompetent Host: Recent Updates About the Epidemiology, Diagnosis, Clinical Manifestations and Management

Dear Colleagues,

In this Special Issue for Pathogens, we would like to focus on recent updates in the research on the epidemiology, diagnosis, clinical manifestations and management of toxoplasmosis in immunocompromised and immunocompetent patients. We are interested in the atypical clinical presentations that toxoplasmosis can have in immunocompromised patients, including those who have undergone hematopoietic stem cell transplant and solid organ transplant, AIDS patients and patients on diverse immunosuppressive/immunomodulatory/biologic agents for diverse malignancies and/or autoimmune diseases, that should increase awareness among health care providers about toxoplasmosis. We would also like to welcome papers on unusual and/or severe clinical manifestations in immunocompetent patients. We want to address the changing epidemiology of toxoplasmosis in different settings, including outbreaks of toxoplasmosis in certain settings/communities and the role of novel diagnostics including molecular diagnostics/metagenomics cell-free DNA and point-of-care tests. We would like to gain insights into the diversity of treatment approaches, the challenges in accessing first line anti-toxoplasma medications and the safety issues with anti-toxoplasma treatment regimens. We encourage diverse types of eligible articles, including reviews, position papers, recommendations/guidelines, systematic reviews and meta-analyses, economic analyses, case reports, case series, cohort studies, case-control studies and clinical trials. The goal of this Special Issue is to bring attention to toxoplasmosis, a neglected infectious disease with high morbidity and mortality in some cases that is nevertheless preventable and treatable.

Dr. Despina G. Contopoulos-Ioannidis
Guest Editor

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