Epidemiology, Diagnosis and Clinical Management of Human Parasitic Infections—2nd Edition

A special issue of Parasitologia (ISSN 2673-6772).

Deadline for manuscript submissions: 31 December 2025 | Viewed by 384

Special Issue Editors


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Guest Editor
Center for Natural and Human Sciences, Universidade Federal do ABC (UFABC), São Bernardo do Campo, São Paulo, Brazil
Interests: Chagas’s disease; leishmaniasis; molecular biology
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
1. Veterinary Medicine Program, Municipal University of São Caetano do Sul (USCS), São Caetano do Sul, Brazil
2. Center for Engineering, Modeling, and Applied Social Sciences, Federal University of ABC, Santo André, Brazil
Interests: toxoplasmosis; trypanosomíases; epidemiology of parasitic diseases
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Anthropogenic movements result in modifications of wild natural habitats, such as the destruction of forest areas, the introduction of domestic animals, and the improvising of sanitation conditions. These changes, associated with global warming, can lead to the uncontrolled proliferation and dispersion of arthropod vectors of parasitic infectious diseases, such as malaria, Chagas disease, and leishmaniasis. Others parasitic diseases are associated with poor sanitation conditions, such as giardiasis, toxoplasmosis, and diseases caused by helminths and flatworms. As a result of the diversity of biomes, the investigation of eco-epidemiological and evolutionary relationships among parasites is important for the detection, prevention, and clinical management of parasitic infectious diseases.

You may choose our Joint Special Issue in Pathogens.

Dr. Marcia Aparecida Speranca
Dr. Aline Diniz Cabral
Guest Editors

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Keywords

  • parasitic infectious diseases
  • eco-epidemiology
  • diagnosis
  • treatment
  • clinical management
  • prevention

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Published Papers (1 paper)

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Research

12 pages, 245 KB  
Article
Helminth and Malaria Co-Infection Among Pregnant Women in Battor and Adidome Towns of the Volta Region of Ghana
by Sarah Alhakimi, Navneet Kaur, Javeriya Choudry, Naa Adjeley Frempong, Charity Ahiabor, William K. Anyan, Abraham K. Anang and Nilanjan Lodh
Parasitologia 2025, 5(3), 44; https://doi.org/10.3390/parasitologia5030044 - 22 Aug 2025
Viewed by 153
Abstract
Aim: In sub-Saharan Africa, approximately 40 million pregnant women are exposed to parasitic diseases such as malaria caused by Plasmodium falciparum, Schistosome parasites, and soil-transmitted helminths (STHs). When parasitic diseases share the same habitat and overlap in distribution, then high co-infection rates [...] Read more.
Aim: In sub-Saharan Africa, approximately 40 million pregnant women are exposed to parasitic diseases such as malaria caused by Plasmodium falciparum, Schistosome parasites, and soil-transmitted helminths (STHs). When parasitic diseases share the same habitat and overlap in distribution, then high co-infection rates occur. The co-infection can lead to consequences for the child, such as intrauterine growth retardation, low birth weight, pre-term delivery, and neonatal mortality. Methods: The objective of the study was to determine the nature and extent of coinfection from 100 samples collected from the Battor (50) and Adidome (50) towns of Ghana in collaboration with the Noguchi Memorial Institute for Medical Research, University of Ghana. Results: Out of 50 for the Adidome towns determined for P. falciparum by Rapid Diagnostic Test (RDT), Malaria Pan-specific Antigen (PAN), and Malaria Pf kit, 39 were true positive (TP), 8 were true negative (TN), and 30 were false negative (FN). For Battor, 19 were TP, 12 TN, and 20 FN. For S. mansoni in Adidome via polymerase chain reaction (PCR) and loop-mediated isothermal amplification (LAMP), 21 tested positive, and 29 were negative, with 52.5% sensitivity and 100% specificity. For S. haematobium, 28 were positive and 22 negative using PCR with 70% sensitivity and 100% specificity. In LAMP, 28 were positive, and 22 negatives, with 70% sensitivity and 100% specificity. In Battor PCR for S. mansoni, 28 positives and 22 negatives with 68.3% sensitivity and 100% specificity. In LAMP, 32 were positive, and 18 were negative, with 80% sensitivity and 100% specificity. For S. haematobium, PCR showed 30 positive and 20 negative, with 73.2% sensitivity and 100% specificity. With LAMP, 21 were positive, and 29 negatives, with 51% sensitivity and 100% specificity. In both towns, 20–30 years had the highest infection prevalence for P. falciparum, S. mansoni, S. haematobium, and Strongyloides stercoralis. Conclusion: The results will be utilized as a part of the continuous surveillance for future research aiming at gathering nationally representative data in Ghana on the prevalence of coinfection and proposing interventions based on that for the vulnerable pregnant women population. Full article
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