Glial Changes in Psychiatric Disorders

Special Issue Editor


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Guest Editor
Division of Molecular Brain Science, Research Institute of Traditional Asian Medicine, Kindai University, Osaka-Sayama, Osaka, Japan
Interests: oligodendrocytes; oligodendrocyte precursor cell; myelin; major depressive disorder; protein methylation; protein phosphorylation; mood disorders; anxiety-like behavior; ER stress response; Golgi stress response; developmental neuroscience; menopause; premenstrual syndrome; memory; learning; dementia; neurotransmitter; neural circuit

Special Issue Information

Dear Colleagues,

Glial cells, including astrocytes, oligodendrocytes, and microglia, are non-neuronal cells in the central nervous system (CNS). While neurons have historically been receiving more attention in the study of psychiatric disorders, several recent studies have shed light on the role of glial cells in these disorders. Although the understanding of glial involvement in psychiatric disorders is still inadequate, recent studies suggest that glial changes may contribute to the pathogenesis or progression of these disorders. Furthermore, these studies indicate the importance of considering glial cells to be potential targets for therapeutic interventions in psychiatric disorders; however, the molecular mechanisms underlying these associations are still not fully understood. The interactions between glial cells and neurons are complex, and further research is needed to elucidate the specific contributions of glial changes to the pathogenesis and progression of various psychic disorders.

Prof. Dr. Shingo Miyata
Guest Editor

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Keywords

  • astrocytes
  • oligodendrocytes
  • microglia
  • depression
  • bipolar disorder
  • schizophrenia
  • stress
  • inflammation
  • COVID-19
  • myelin

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