Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
3.9
2.0
Journals
MPs
Special Issues
Analytical Methods in Natural Sciences and Archaeometry
share announcement

Analytical Methods in Natural Sciences and Archaeometry

A special issue of Methods and Protocols (ISSN 2409-9279).

Deadline for manuscript submissions: 30 September 2026 | Viewed by 1414

Special Issue Editors

Dr. Nikolaos A. Kazakis

E-Mail Website
Guest Editor
Laboratory of Archaeometry and Physicochemical Measurements, Athena Research Center in Information, Communication and Knowledge Technologies, Xanthi, Greece
Interests: archaeometry; luminescence; dosimetry; characterization; chemical engineering; circular economy
Dr. Lamprini Malletzidou

E-Mail Website
Guest Editor
Laboratory of Archaeometry and Physicochemical Measurements, Athena Research Center in Information, Communication and Knowledge Technologies, Xanthi, Greece
Interests: pigments; binders; spectroscopy; aging; dating
Special Issues, Collections and Topics in MDPI journals
Dr. Nikolaos Laskaris

E-Mail Website
Guest Editor
Department of Industrial Desing and Production Engineering, University of West Attica, GR-12241 Athens, Greece
Interests: archaeometry; absolute dating; material characterization
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Ongoing advancements emerge within the broad field of Natural Sciences, continuously pushing the existing boundaries towards sensitivity, precision, and non-destructive analysis. Furthermore, existing methods and protocols are redefined, enhancing our knowledge of the natural world and materials crafted by human hands.

Archaeometry, as an interdisciplinary science where Natural Sciences meet, bridges the gap between analytical techniques and cultural heritage studies, offering innovative approaches to the study and conservation of historical artifacts, structures, and environments, emphasizing in situ and/or non-destructive measurements and sample quantity minimization. This synergy drives the development of robust and adaptive methods that are applicable across diverse scientific domains.

This Special Issue of Methods and Protocols, entitled “Analytical Methods in Natural Sciences and Archaeometry”, aims to provide a comprehensive overview of the latest advancements and applications of said fields. We invite researchers and scientists to submit original research, review articles, and methodological papers that present new or updated methods/techniques in the fields of Physics, Chemistry, Biology, Geology, Computational Methods and Archaeometry that enhance our understanding of processes and materials. Submissions should be related to the collection, analysis and interpretation of data in the above fields, aiming to shed light on the composition or the properties of the materials studied. Special emphasis will be placed on novel approaches that promote interdisciplinary collaboration, sustainability, and accuracy.

By bringing together cutting-edge research and practical insights, this collection aims to highlight the pivotal role of analytical methods in expanding our knowledge and fostering innovation across the natural and human-made world.

We look forward to receiving your contributions.

Dr. Nikolaos A. Kazakis
Dr. Lamprini Malletzidou
Dr. Nikolaos Laskaris
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Methods and Protocols is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • spectroscopy
  • microscopy
  • chromatography
  • X-rays
  • thermal analysis
  • luminescence
  • machine learning

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.

Further information on MDPI's Special Issue policies can be found here.

Published Papers (2 papers)

Download All Papers
Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Research

10 pages, 1163 KB  
Article
A Rapid LC–MS/MS Method for Quantification of Biogenic Amines in Meat: Validation and Application for Food Safety Monitoring
by Giulia Rampazzo, Giacomo Depau, Giampiero Pagliuca, Elisa Zironi, Andrea Serraino, Federica Savini and Teresa Gazzotti
Methods Protoc. 2025, 8(5), 106; https://doi.org/10.3390/mps8050106 - 10 Sep 2025
Viewed by 352
Abstract
Biogenic amines (BAs) are nitrogenous compounds naturally present in protein-rich foods, whose accumulation may indicate spoilage and pose health risks. This study presents the development and validation of a rapid LC–MS/MS method for the simultaneous quantification of six BAs—putrescine (PUT), cadaverine (CAD), histamine [...] Read more.
Biogenic amines (BAs) are nitrogenous compounds naturally present in protein-rich foods, whose accumulation may indicate spoilage and pose health risks. This study presents the development and validation of a rapid LC–MS/MS method for the simultaneous quantification of six BAs—putrescine (PUT), cadaverine (CAD), histamine (HIS), tyramine (TYR), spermidine (SPD), and spermine (SPM)—in meat products, without requiring derivatisation. Sample preparation was optimized to enhance extraction efficiency and reproducibility, using 0.5 M HCl and a double-centrifugation protocol to avoid matrix interference. Chromatographic separation was optimized using a C18 column and acidified ammonium formate/acetonitrile mobile phases. The method showed good linearity (R2 > 0.99), trueness between −20% and +20%, and acceptable precision (RSDr and RSDR ≤ 25%). Limits of quantification were established at 10 µg/g for all analytes. The method was applied to ten commercial meat samples, where PUT, TYR, and SPD were the most frequently detected amines. Although HIS and TYR levels were below toxicological thresholds for healthy individuals, one sample showed TYR levels potentially concerning for monoamine oxidase inhibitors -treated consumers. The Biogenic Amine Index (BAI) further supported product quality assessment, identifying early spoilage in selected cases. This method offers a rapid, robust and efficient tool for routine monitoring of BAs in meat products, supporting food safety and quality control initiatives. Full article
(This article belongs to the Special Issue Analytical Methods in Natural Sciences and Archaeometry)
►▼ Show Figures

Figure 1

22 pages, 6643 KB  
Article
Analysis of the Effect of the Tablet Matrix on the Polymorphism of Ibuprofen, Naproxen, and Naproxen Sodium in Commercially Available Pharmaceutical Formulations
by Edyta Leyk, Marcin Środa, Gracjan Maślanka, Patrycja Nowaczyk, Amelia Orzołek, Hanna Grodzka, Aleksandra Kurek, Olaf Knut, Julia Michalak, Jonatan Płachciak and Alina Plenis
Methods Protoc. 2025, 8(5), 99; https://doi.org/10.3390/mps8050099 - 1 Sep 2025
Viewed by 439
Abstract
Pharmaceutical formulations, in addition to the medicinal substance(s), contain added excipients that make it possible to create a pharmaceutical product that exhibits required properties in terms of mechanical, physical, chemical, and microbiological stability. Additionally, these substances can act as release modifiers or improve [...] Read more.
Pharmaceutical formulations, in addition to the medicinal substance(s), contain added excipients that make it possible to create a pharmaceutical product that exhibits required properties in terms of mechanical, physical, chemical, and microbiological stability. Additionally, these substances can act as release modifiers or improve bioavailability parameters. Literature data indicate that excipients, especially polymeric ones, can also affect the polymorphism of the active substance, resulting in drug bioavailability enhancement or reduction. This influence can be evaluated using thermal and spectroscopic methods. In the study, differential scanning calorimetry (DSC), vibrational spectroscopic studies (Fourier transform infrared spectroscopy, FTIR), Raman spectroscopy, and X-ray diffraction (XRD) assay of ibuprofen, naproxen, and naproxen sodium standards and pharmaceutical preparations containing these medicinal substances in their compositions were carried out. DSC results indicated that a sharp melting peak was observed on the DSC curves of the standards, confirming their crystalline form. DSC results obtained for pharmaceutical formulations also indicated that the enthalpy of melting is sometimes lower than calculated from the percentage of active ingredients in the formulations. In addition, the melting peak is often broadened and shifted toward lower temperatures, suggesting the influence of excipients on the polymorphism of drug substances. The FTIR and Raman spectra of pharmaceutical formulations contained all characteristics of the active substances. XRD analysis was also performed. Therefore, possible chemical interactions between the components of the preparations have been excluded. At the same time, FTIR and Raman spectroscopy results as well as XRD assay showed a reduction in the height of signals corresponding to the crystalline API form, confirming the possibility of reducing API crystallinity in pharmaceutical formulations. Full article
(This article belongs to the Special Issue Analytical Methods in Natural Sciences and Archaeometry)
►▼ Show Figures

Figure 1

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-2
Back to TopTop