SARS-CoV-2 and HIV: Current Perspectives and Challenges
A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Virology".
Deadline for manuscript submissions: closed (30 June 2023) | Viewed by 468
Special Issue Editors
Interests: HIV infection; COVID-19; SARS-CoV-2 specific T cell response; SARS-CoV-2 IgG neutralizing antibodies; HIV-specific inflammation; HIV-specific immune activation; microbial translocation
Interests: HIV infection; COVID-19; post-acute sequelae of SARS-CoV-2 infection HIV-associated neurocognitive disorders; monoclonal antibodies for SARS-CoV-2 infection
Interests: HIV infection; COVID-19; SARS-CoV-2 specific T cell response; SARS-CoV-2 IgG neutralizing antibodies; HIV-specific inflammation; HIV-specific immune activation; microbial translocation
Special Issue Information
Dear Colleagues,
Given their increased risk of severe complications following common respiratory viral infections, such as influenza, HIV-positive patients were initially thought to be at increased risk of a more severe course of SARS-CoV-2 infection.
However, the first studies failed to demonstrate an increased risk of SARS-COV-2 infection and of severe clinical course in HIV-infected patients. As regards immunological response to natural infection or to vaccination, however, other preliminary studies describe a lower total SARS-CoV-2 specific IgG neutralizing antibody concentrations following natural infection and dysfunctional vaccine response in persons living with HIV.
The aim of this Special Issue of Microorganisms is to better describe the clinical course of COVID-19, the innate and acquired immune response to SARS-CoV-2 infection and the humoral response to COVID-19 vaccination in HIV-positive patients, compared to HIV-negative controls. Articles that describe aspects of SARS-CoV-2 specific immune response following natural infection and the available vaccines in HIV-positive patients are particularly sought.
The manuscripts included in this Special Issue should provide a larger and more detailed overview of the magnitude, functionality, and durability of the immune responses to SARS-CoV-2 infection, as well as inform strategies of targeted therapeutic interventions and vaccine schedules, in HIV-infected individuals.
Prof. Dr. Giulia Marchetti
Dr. Francesca Bai
Dr. Roberta Rovito
Guest Editors
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Keywords
- HIV infection
- SARS-CoV-2 infection
- HIV/SARS-CoV-2 coinfection
- post-acute sequelae of SARS-CoV-2 infection
- SARS-CoV-2 IgG neutralizing antibodies
- antibody and memory B cell response following COVID-19 vaccination
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