Advances in Public Health Microbiology 2024

A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Public Health Microbiology".

Deadline for manuscript submissions: 30 June 2024 | Viewed by 486

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Centro Operativo Veterinario per l'Epidemiologia, Programmazione, Informazione e Analisi del Rischio (COVEPI), National Reference Center for Veterinary Epidemiology, Istituto Zooprofilattico Sperimentale, dell'Abruzzo e del Molise "G. Caporale", Campo Boario, 64100 Teramo, Italy
Interests: epidemiology of animal infectious diseases and zoonoses; risk assessment studies; molecular epidemiology studies on viruses and bacteria; designing surveillance systems for infectious diseases; field epidemiology training; food borne zoonotic diseases
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Special Issue Information

Dear Colleagues,

This Special Issue is the continuation of our previous Special Issue, entitled

https://www.mdpi.com/journal/microorganisms/special_issues/8Y208038D0.

This Special Issue aims to collect high-quality review papers in all fields related to Public Health Microbiology. We encourage researchers to contribute papers (comprehensive reviews and research articles) that highlight the latest developments in the field of Public Health Microbiology, or to invite relevant experts and colleagues to do so.

Dr. Paolo Calistri
Guest Editor

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Keywords

  • public health
  • microbiology
  • infectious diseases

Published Papers (1 paper)

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Research

10 pages, 399 KiB  
Article
Selective Pressure and Evolution of SARS-CoV-2 Lineages BF.7 and BQ.1.1 Circulating in Italy from July to December 2022
by Alessandra Lo Presti, Luigina Ambrosio, Angela Di Martino, Arnold Knijn, Luca De Sabato, Gabriele Vaccari, Ilaria Di Bartolo, Stefano Morabito, Anna Teresa Palamara, Paola Stefanelli and on behalf of the Italian Genomic Laboratory Network
Microorganisms 2024, 12(5), 908; https://doi.org/10.3390/microorganisms12050908 - 30 Apr 2024
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Abstract
In this work, we studied the selective pressure and evolutionary analysis on the SARS-CoV-2 BF.7 and BQ.1.1 lineages circulating in Italy from July to December 2022. Two different datasets were constructed: the first comprised 694 SARS-CoV-2 BF.7 lineage sequences and the second comprised [...] Read more.
In this work, we studied the selective pressure and evolutionary analysis on the SARS-CoV-2 BF.7 and BQ.1.1 lineages circulating in Italy from July to December 2022. Two different datasets were constructed: the first comprised 694 SARS-CoV-2 BF.7 lineage sequences and the second comprised 734 BQ.1.1 sequences, available in the Italian COVID-19 Genomic (I-Co-Gen) platform and GISAID (last access date 15 December 2022). Alignments were performed with MAFFT v.7 under the Galaxy platform. The HYPHY software was used to study the selective pressure. Four positively selected sites (two in nsp3 and two in the spike) were identified in the BF.7 dataset, and two (one in ORF8 and one in the spike gene) were identified in the BQ.1.1 dataset. Mutation analysis revealed that R408S and N440K are very common in the spike of the BF.7 genomes, as well as L452R among BQ.1.1. N1329D and Q180H in nsp3 were found, respectively, at low and rare frequencies in BF.7, while I121L and I121T were found to be rare in ORF8 for BQ.1.1. The positively selected sites may have been driven by the selection for increased viral fitness, under circumstances of defined selective pressure, as well by host genetic factors. Full article
(This article belongs to the Special Issue Advances in Public Health Microbiology 2024)
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