Advances in Arenaviruses Research
A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Virology".
Deadline for manuscript submissions: 31 March 2026 | Viewed by 5
Special Issue Editor
Special Issue Information
Dear Colleagues,
The Arenavirus family encompasses several viruses capable of causing severe and often fatal zoonotic diseases in humans. Notable pathogens include Lassa virus, Lujo virus, Junín virus, Machupo virus, Guanarito virus, Sabia virus and Chapare virus. These viruses are primarily transmitted through direct contact with infected rodents or inhalation of their excreta. Cases of human-to-human transmission have also been documented. The prototype Lymphocytic choriomeningitis virus is increasingly recognized as a neglected human pathogen. Despite the risks posed by arenaviruses to public health, effective vaccines and treatments remain limited. Accordingly, several arenaviruses are classified as Category A pathogens by the Centers for Disease Control (USA). Lassa virus is listed as a priority pathogen by the World Health Organization under its R&D Blueprints.
Significant knowledge gaps remain in our understanding of pathogenic arenaviruses, particularly in virology, pathogenesis, immunology, virus-host interaction, epidemiology, and transmission for pathogenic arenaviruses. Additional challenges in the field include the urgent need for rapid diagnosis kits with high detection specificity and sensitivity, establishment of robust surveillance networks, development of relevant animal models as well as effective, ideally broad-spectrum, vaccines and countermeasures.
This special issue calls for original research or review papers to address these knowledge gaps and challenges in the field, with the ultimate goal of improving prevention, diagnosis, and treatment strategies against arenavirus infection.
Dr. Cheng Huang
Guest Editor
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Keywords
- virus infection
- virus replication
- tropism
- pathogenesis
- immune response
- animal models
- therapeutics
- vaccines
- diagnostics
- resevoir
- epidemiology
- phylogenetics
- transmissions
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