Respiratory Diseases and Microbiome Dysbiosis
A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Microbiomes".
Deadline for manuscript submissions: 30 November 2025 | Viewed by 36
Special Issue Editors
Interests: human microbiome; dysbiosis; chronic inflammatory diseases; cancer; drug development; multi-omics; translational studies
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Respiratory disorders encompass a variety of conditions that affect lung function and breathing. The airway microbiome consists of various microorganisms, such as bacteria, fungi, and viruses, that play a crucial role in respiratory health by protecting against pathogens and regulating immune responses. Research has shown that imbalances in this microbial community (dysbiosis) can disrupt homeostasis, further complicating respiratory infections and chronic diseases. Moreover, the gut microbiota plays a pivotal role in modulating systemic and pulmonary immunity through the gut–lung axis. However, intestinal and airway microbiome dysbiosis disturbs this bidirectional crosstalk and influences respiratory health by contributing to immune dysfunction, inflammation, and ultimately the exacerbation of respiratory illness and comorbidities such as allergies. Drugs commonly used to treat patients, including antibiotics and oral corticosteroids, have a strong effect on microbiota structure. Research on the gut–lung axis underscores the importance of microbial diversity and its systemic impact on clinical manifestations and therapeutic outcome. Understanding these interactions may pave the way for the development of novel biomarkers and microbiome-based therapies for the prevention and management of chronic respiratory diseases, addressing not only the severity of symptoms but also allergic reactions and other coexisting conditions.
This Special Issue aims to highlight the dynamics of the microbiome in respiratory diseases and set a rational basis for personalized strategies to improve patient health. To this end, we invite authors to submit research articles, reviews, or case reports on a wide range of topics related to microbiome dysbiosis, host–microbiome interactions, and microbiota-targeting therapeutics in the context of respiratory disorders.
Dr. Heleni Loutrari
Dr. Paraskevi Katsaounou
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Microorganisms is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- upper and lower airway disorders
- microbiome
- inflammation
- immune response
- infections
- allergies
- dysbiosis
- gut–lung axis
- metagenomics
- multi-omics
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