Bioactive Substances, Gut Microbiome, and Host Health
A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Gut Microbiota".
Deadline for manuscript submissions: closed (15 January 2025) | Viewed by 11916
Special Issue Editors
Interests: gut; microbiology; health; nutrition; immunity
Special Issue Information
Dear Colleagues,
The complex interactions occurring between gut microbes and the host are recognized as comprising one of the key factors regulating host health. With the developments in molecular tools and technologies, namely, metagenomics, metabolomics, and transcriptomics, the complex interactions that occur between the host and different microorganisms are gradually being explained. The dysregulation of the gut flora indicates that various pathways involved in immunity, energy, and lipid and glucose metabolism are compromised, leading to a range of diseases, such as obesity, osteoporosis, and cardiovascular diseases.
More and more studies have confirmed that a variety of bioactive substances can be used to maintain the health of the human host. Their roles include modulating the composition, diversity, and activity of the gut microbiota, improving the homeostasis of the gut microbiota and maintaining the integrity of the intestinal barrier, and participating in nutrient metabolism, immune regulation, and energy supply, directly or indirectly, through the activation or inhibition of multiple signaling pathways between the gut microbiota and the receptors of the host cells. This enhances the immune mechanism, regulates the energy balance, and helps the defense against pathogens.
In this Special Issue, we will focus on the effects of bioactive substances on the gut microbiome. We encourage you to submit your latest research results or review articles in order to contribute to the knowledge on the key role played by bioactive substances in regulating the gut microbiota. Topics can include:
- The interaction between the gut microbiota and bioactive substances;
- Gut microbiota dysbiosis and disease development;
- The role of bioactive substances in regulating the gut microbiota;
- The mechanisms of bioactive substances in nutrient metabolism and immune regulation;
- The regulation of energy balance and immune mechanisms by the gut microbiota;
- Prospects for applications of bioactive substances in the maintenance of human host health.
Prof. Dr. Gang Liu
Guest Editor
Dr. Tianwei Wang
Guest Editor Assistant
Manuscript Submission Information
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Keywords
- bioactive substances
- gut microbiome
- immunity
- metabolism
- diseases
- health
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