Emerging Trends in Next-Generation Vaccines to Combat Infectious Diseases

Dear Colleagues,

Vaccination against emerging and re-emerging infectious diseases is crucial for combating epidemics and pandemics. The mRNA vaccines, following the COVID-19 pandemic, have emerged as a promising technology for developing rapid, efficacious, and safer vaccines against infectious or zoonotic diseases that affect both animals and humans. Packaging mRNA for targeted delivery requires the exploration and optimization of carriers. While lipid nanoparticles (LNPs) have been clinically validated for the encapsulation and delivery of mRNA, several other tools, including but not limited to virus-like particles (VLPs), noroviruses, and extracellular vesicles, among others, are currently under investigation to explore their potential and clinical validity. Additionally, ferritin nanoparticle-based antigen presentation has yielded promising pre-clinical results for the mucosal delivery of several vaccine antigens, some of which are currently under clinical trials.

This Special Issue aims to provide a platform for the rapid dissemination of pre-clinical research results in the field of vaccine development. The submission of original research articles, reviews, brief reports, and communications is encouraged. This Special Issue encourages the submission of articles related to the following:

i. mRNA vaccines;

ii. Recombinant vaccines;

iii. Vaccines for veterinary use;

iv. Novel approaches in antigen presentation and delivery;

v. Emerging and re-emerging infectious diseases.

Dr. Ravendra P. Chauhan
Guest Editor

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