Microbiomes in Human Health and Diseases

A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Microbiomes".

Deadline for manuscript submissions: 31 March 2026 | Viewed by 17

Special Issue Editor


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Guest Editor
1. Department of Microbiology, Division of Laboratory Medicine, Oslo University Hospital, 0372 Oslo, Norway
2. Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, 141 86 Stockholm, Sweden
Interests: genomics and metagenomics; microbiome; infectious diseases; Shiga toxin-producing Escherichia coli
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Special Issue Information

Dear Colleagues,

The human microbiome—the collective microorganisms inhabiting in and on the human body and their genes/products—is a pivotal determinant of health and disease through various mechanisms, including influencing digestion, immunity, metabolism, production of hormones, neurotransmitters, etc. Consequently, the human microbiome has been linked to diverse conditions, including metabolic, gastrointestinal, autoimmune, neurological, and infectious diseases. However, significant knowledge gaps persist in the field. Current research predominantly focuses on bacterial communities (bacteriome), particularly in the gut, while microbiome in other niches (e.g., skin, respiratory tract, and urogenital) and other microbial kingdoms beyond bacteria (e.g., viruses, archaea, and fungi) remain understudied. Furthermore, the mechanisms of microbial communications across body sites and their integrated roles in host physiology are poorly understood so far.

The aim of this Special Issue is to showcase cutting-edge research advancing our understanding of how resident microbial communities influence host physiological functions and contribute to health and disease pathogenesis. We welcome original research and reviews providing insights into the microbiome and its role in human health and disease conditions, with emphasis on host–microbiome interactions, multi-kingdom microbial dynamics, and cross-niche microbiome communications, highlighting the translational potential for microbiome-based diagnostics and therapeutics.

Dr. Xiangning Bai
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Microorganisms is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • microbiome
  • health and disease
  • immunity
  • metabolism
  • microbiome-directed diagnostics and therapeutics

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Published Papers

This special issue is now open for submission.
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