HIV Infections: Comorbidities, Clinical Challenges, and Antiretroviral Advances
A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Virology".
Deadline for manuscript submissions: 31 March 2026 | Viewed by 6
Special Issue Editors
Interests: aging; circadian rhythm; COVID-19; emerging infection; inflammaging; HIV-infection; senolytics; senescence; virus infection
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
HIV care has moved beyond achieving an undetectable viral load to the lifelong management of multimorbidity. As people living with HIV age, cardiometabolic disease, neurocognitive impairment, malignancies, mental health conditions, and frailty increasingly shape clinical outcomes. These comorbidities intersect with antiretroviral therapy through chronic inflammation, polypharmacy, drug–drug interactions, and adherence constraints, revealing gaps in screening, risk stratification, and models of care. This Special Issue centers on the interface between comorbidities and ART, and the practical challenges clinicians face across diverse settings.
We invite submissions that characterize comorbidity phenotypes and trajectories, quantify excess risks, and evaluate preventive and therapeutic strategies, including long-acting regimens, treatment simplification, and regimen switching, while also addressing implementation barriers and health inequities.
Eligible contributions include randomized and pragmatic trials, cohort and registry analyses, real-world evidence, translational studies on biomarkers and immune activation, pharmacology and interaction studies, decision-analytic modeling, and qualitative research centered on patient experience. Work focusing on priority populations (older adults, women, and migrants), coinfections (HBV/HCV and tuberculosis), and topics such as low-level viraemia, resistance, or integrated care pathways is encouraged.
Dr. José Ramón Blanco
Dr. Enrique Bernal-Morell
Guest Editors
Manuscript Submission Information
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Keywords
- HIV
- HIV multimorbidity
- antiretroviral therapy
- coinfections
- viraemia
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