Immune Responses to Toxoplasma Infections
A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Public Health Microbiology".
Deadline for manuscript submissions: 20 February 2026 | Viewed by 37
Special Issue Editor
Interests: Toxoplasma gondii; ionizing radiation; vaccine development; intestinal immunity; irradiated toxins; serology and laboratory diagnosis
Special Issue Information
Dear Colleagues,
Toxoplasmosis, first identified over a century ago, remains a complex and pressing global health concern. It is estimated that up to one-third of the world’s population has been exposed to Toxoplasma gondii, with seroprevalence rates exceeding 60% in some regions—often without symptoms. Food-producing animals represent a critical reservoir for the parasite, leading not only to significant economic losses but also posing a risk of transmission to humans through the food chain.
Understanding the immune response and the parasite’s biological dynamics is extremely important for the development of future therapeutic and vaccine approaches. As the primary entry point of this disease into the body is the oral route, studying the mucosal response is crucial for establishing protection within this unique immunological environment—the mucosae. Equally important is the systemic study of the immune response, which is crucial for understanding how to combat the infection before the parasite escapes into host cells. Gaining insight into how to modulate the immune response to improve the efficiency of combating Toxoplasma gondii is both fundamental and necessary for advancing the study of this host–parasite interaction.
Dr. Andres J. Galisteo Junior
Guest Editor
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Keywords
- toxoplasmosis
- vaccine
- immune response
- mucosal immunity
- infection
- humoral immunity
- cell-mediated immunity
- chronic infection
- immunocompromised
- antigen presentation
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