Molecular Mechanisms of Resistance to Antifungals
A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Antimicrobial Agents and Resistance".
Deadline for manuscript submissions: 15 July 2026 | Viewed by 22
Special Issue Editors
Interests: antifungal resistance; antifungal susceptibility testing; antifungal therapy; One Health; phytopathology; laboratory diagnosis of mycosis
Interests: pathogenic fungi; speciation; genetic variability; virulence; autocatalitic genetic elements
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The antifungal therapeutic arsenal, particularly for invasive fungal infections, is limited. It is currently restricted to three primary classes: polyenes (e.g., amphotericin B), azoles (e.g., fluconazole, itraconazole, among others), and echinocandins (e.g., caspofungin, anidulafungin, and the most recent, rezafungin). However, adverse effects, high treatment costs, and low investment in the discovery of new antifungals have generated global concern regarding antifungal pharmacotherapy. Compounding this scenario, the literature reports an increase in resistant strains, such as azole-resistant Aspergillus fumigatus, as well as the emergence of multidrug-resistant species, such as Candidozyma auris. Consequently, the surveillance of these resistant strains and a deeper understanding of the molecular mechanisms of antifungal resistance are imperative. Thus, this Special Issue aims to gather research that advances knowledge on this subject, with the goal of supporting the bioprospecting of new antifungal agents and informing public policies
Dr. Felipe Queiroga Sarmento Guerra
Dr. Raquel Cordeiro Theodoro
Guest Editors
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Keywords
- antifungal therapeutic
- invasive fungal infections
- molecular mechanisms
- antifungal resistance
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