Application of Antimicrobials and Biofilm-Associated Infections
A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Biofilm".
Deadline for manuscript submissions: 30 September 2026
Special Issue Editor
Interests: Antimicrobial; Biofilm; Bacteria
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
This Special Issue on the "Application of Antimicrobials and Biofilm-Associated Infections" aims to address the management and eradication of biofilm-associated infections. These infections present a significant challenge in clinical settings due to their inherent tolerance to antimicrobial agents and the complexities involved in successfully treating such infections. Biofilms are surface-adherent and aggregated structured communities of bacteria encased in extracellular polymeric substances (EPSs), which shield them from both host immune responses and antimicrobial treatments. Moreover, traditional antibiotics often prove inadequate in eradicating biofilm-associated infections due to the physiological states of the bacteria. The multifaceted interactions within biofilms such as microbial synergy, quorum sensing, and the matrix’s protective role against therapeutic agents contribute to their resilience. Therefore, innovative strategies targeting multiple pathogens in mixed populations and considering the multifaceted interactions that are established in the biofilm community need to be evaluated. Innovative effective strategies include the disruption of biofilm matrix components, the use of novel antimicrobials and delivery systems, the targeting of quorum sensing, and others including combinatorial approaches to enhance treatment efficacy. Thus, we invite researchers to contribute original articles, reviews, and clinical studies that explore novel approaches, clinical implications, and the underlying biological mechanisms related to biofilms and antimicrobial application. This Special Issue will foster a deeper understanding of biofilm dynamics and encourage the development of effective strategies for managing these pervasive infections.
Dr. Semih Esin
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Microorganisms is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- biofilm
- quorum sensing
- persister cells
- chronic infections
- antimicrobial resistance
- antibiofilm agents
- combination therapy
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
