The Latest Research on Human Papillomavirus

A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Virology".

Deadline for manuscript submissions: 31 July 2026 | Viewed by 939

Special Issue Editors


E-Mail Website
Guest Editor
Laboratory of Cell Biology and Histology, Faculty of Medicine and Health Sciences, University of Antwerp, 2610 Antwerp, Belgium
Interests: cancer

E-Mail Website
Guest Editor
Discipline of Public Health Medicine, School of Nursing and Public Health, University of KwaZulu-Natal, Durban 4000, South Africa
Interests: epidemiology; public health; cancer

E-Mail Website
Guest Editor Assistant
Department of Virological Pathology, Sefako Makgatho Health Sciences University, Pretoria 0204, South Africa
Interests: virology; HPV; vaccination; HIV; molecular biology; cervical cancer; medicine; self sampling; vaccine preventable diseases; hepatitis B virus; HIV epidemiology; HIV drug resistance; HPV testing; HPV mRNA; viral STIs; HPV vaccination uptake; cervical cancer screening

Special Issue Information

Dear Colleagues,

Human papillomavirus (HPV) is associated with a wide range of diseases that impose a significant global burden not only on health but also on societies and economies. The virus causes diseases of the anogenital, skin, and oral regions of the body, in addition to other organs. These diseases contribute to high mortality and morbidity rates, with cervical cancer, in particular, being especially prominent in sub-Saharan Africa. Thus, recent HPV research has focused on improving prevention, early detection, improving treatment outcomes, and understanding its role in cancer progression.

Liquid-based cytology and HPV DNA testing for cervical cancer screening have been gaining traction in sub-Saharan Africa, whereas self-sampling for HPV DNA testing is rising as a strategy to improve cervical cancer screening. Furthermore, some studies have focused on whole-genome sequencing, which has allowed researchers to both study integration patterns that are linked to the development of cancer and track viral variants. Nevertheless, more investigations of methods to identify transforming infections in order to improve diagnosis and reduce overtreatment are paramount. Additionally, for the prevention of HPV infection and cervical cancer, an update on the challenges of HPV vaccination, especially in low- and middle-income countries, is of importance in order to meet the WHO’s 2030 goals. Thus, the aim of this Special Issue is to provide a platform for researchers working on HPV across diverse disciplines to exhibit their latest research and share new insights on HPV research.

We welcome original research manuscripts, method-based articles, and reviews that highlight the latest HPV research across a variety of disciplines.

Prof. Dr. Johannes Paul Bogers
Prof. Dr. Themba G Ginindza
Guest Editors

Dr. Ramokone Lebelo
Guest Editor Assistant

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Microorganisms is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • HPV
  • molecular biology
  • HPV epidemiology
  • HPV drug resistance

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.

Further information on MDPI's Special Issue policies can be found here.

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Research

13 pages, 610 KB  
Article
The Relationship Between Body Mass Index and Cervical High-Risk HPV Positivity in Women: A Single-Center Study
by Cemal Çiçek, Mehmet Alican Sapmaz, Ayfer Bakır, Elif Tuğçe Güner and Murat Aral
Microorganisms 2026, 14(3), 555; https://doi.org/10.3390/microorganisms14030555 - 28 Feb 2026
Viewed by 542
Abstract
Background: Human papillomavirus (HPV) is the primary etiological agent of cervical cancer. Although obesity has been proposed as a factor influencing HPV acquisition and disease course through immune and metabolic mechanisms, its role remains controversial. This study aimed to evaluate the association between [...] Read more.
Background: Human papillomavirus (HPV) is the primary etiological agent of cervical cancer. Although obesity has been proposed as a factor influencing HPV acquisition and disease course through immune and metabolic mechanisms, its role remains controversial. This study aimed to evaluate the association between body mass index (BMI) and high-risk (HR)-HPV infection, including genotype distribution, infection type, and cytological findings. Methods: This cross-sectional study included women aged 21 years and older who underwent cervical sampling between August and November 2025. Participants were classified as non-obese (BMI <30 kg/m2) or obese (BMI ≥30 kg/m2). HR-HPV genotypes were detected using a multiplex real-time PCR method, and cytological evaluation was performed according to the Bethesda Cervical Cytology Reporting System. Results: Among 518 women, the overall HR-HPV positivity rate was 13.5%. No significant difference in HR-HPV positivity was observed between obese (11.6%) and non-obese (14.2%) women (OR = 0.79; 95% CI: 0.44–1.44; p = 0.452). After age adjustment, obesity was not identified as an independent risk factor for HR-HPV infection. BMI was not associated with HPV genotype distribution, infection type, or cytological findings (all p > 0.05). HPV-68 was the most frequently detected genotype. Conclusions: BMI was not independently associated with HR-HPV infection or related clinical and cytological features. These findings suggest that HPV infection is primarily influenced by viral characteristics and host immune response, while BMI appears to play a limited role. Further multicenter prospective studies are needed to clarify the impact of obesity on HPV infection. Full article
(This article belongs to the Special Issue The Latest Research on Human Papillomavirus)
Show Figures

Figure 1

Back to TopTop