Bacterial Genetics and Antibiotic Resistances
A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Antimicrobial Agents and Resistance".
Deadline for manuscript submissions: 30 June 2026 | Viewed by 84
Special Issue Editors
Interests: microbial physiology; environmental stresses; bacterial genetics; gene regulation; transcriptional regulators; biofilm; proteomics; biofuels; bioengineering; metabolites
Interests: antibiotic resistance; multidrug resistance; lysine acetylation; KAT; KDAC; histone-like proteins; post-translational modifications; mass spectrometry; proteomics; antimicrobial peptides; biofilm
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Central to human life, DNA hosts the master blueprint of most cellular functions in bacteria. Natural selection causes DNA to evolve constantly and rapidly, which plays a significant role in the emergence of new traits including antibiotic resistance. To adjust to antibiotic pressure, bacteria employ several strategies. These include spontaneous mutations in their DNA including gene duplication, genetic rearrangement and the acquisition of resistance genes from other bacteria through horizontal gene transfer mechanisms. Mutation in DNA can enhance efflux pump activity, alter drug targets and changes in gene expression level to tolerate drug regimens and cause resistance. Indeed, genetic flexibility combined with selective pressure from widespread antibiotic use has led to the evolution of multidrug-resistant strains that threaten our ability to treat common infections. Thus, understanding the genetics and molecular mechanism of antibiotic resistance is essential for tackling drug-resistant superbugs, developing new antimicrobial strategies and implementing effective surveillance and stewardship initiatives.
This Special Issue provides a platform for researchers to publish their research and share information on the role of bacterial genetics in drug resistance development. It will publish reviews and research articles on topics such as the following:
- Exploration of genomics and gene function of drug-resistant bacteria to understand mechanisms of drug resistance development;
- Genetic interactions and network of drug resistance genes;
- Analysis of mutations causing genetic and phenotypic variations contributing to drug resistance;
- Epigenetics and gene expression profiling in response to antimicrobials and identification of novel drug targets;
- Novel antibacterial strategies targeting gene function and the development of drug resistance in bacteria.
We look forward to receiving your contributions.
Dr. Santosh Kumar
Dr. Valerie Carabetta
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Microorganisms is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- bacterial genetics and epigenetics
- gene function and gene regulation
- antibiotic resistance genes
- efflux pumps
- novel drug-targets
- multidrug-resistant strains
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