Microbial Regulation of Host Metabolism
A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Microbiology and Ecological Metabolomics".
Deadline for manuscript submissions: 15 April 2026 | Viewed by 125
Special Issue Editor
Interests: metabolic dysfunction; obesity; sarcopenia; probiotics; prebiotics; postbi-otics; gut microbiota; metabolites; microbiome; physiological function
Special Issue Information
Dear Colleagues,
This Special Issue highlights advances in host metabolism driven by microbiome technologies and the molecular microbiological regulation of diverse metabolites.
The gut microbiota exerts profound effects on host metabolic regulation by producing key metabolites such as short-chain fatty acids, bile acids, and vitamins. This specific changes in the microbiome impact key metabolic processes, including glucose and lipid metabolism, insulin sensitivity, energy homeostasis, and immune diseases, and may serve as therapeutic targets for human diseases. We welcome studies leveraging host–microbe interactions, bioinformatics to elucidate microbial diversity, and functional mechanisms at the molecular level. Topics include, but are not limited to, the following:
- Short-chain fatty acid (SCFA) metabolite production and microbial regulation mechanisms;
- Targeted metabolomics of metabolites of natural products, including probiotics and natural products;
- Microbial bile acid metabolism and host signaling pathways such as the FXR;
- Host energy metabolism through the production of essential vitamins, branched-chain amino acids, and indole propionate by microbes;
- Metabolic regulation of gut hormone secretion (GLP-1, PYY, GIP, 5-HT, etc.) by microbial metabolites.
This Special Issue will focus on recent research that reports the relevance of biomolecular regulatory mechanisms through various factors of host–microbiota interactions. Through the contributions of original research papers and review articles, researchers are able to understand these molecular mechanisms and offer promising future strategies for treating diseases caused by dysbiosis.
Dr. Kippeum Lee
Guest Editor
Manuscript Submission Information
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Keywords
- gut microbiota-derived metabolites
- short-chain fatty acids (SCFAs)
- gut hormones
- bile acid
- probi-otics
- postbiotics
- gut microbiota
- microbiome
- physiological function
- metabolism balance
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