Harnessing Cancer Metabolism: Unveiling New Therapeutic Approaches and Diagnostic Tools
A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Cell Metabolism".
Deadline for manuscript submissions: 30 April 2026 | Viewed by 2
Special Issue Editors
Interests: metabolic alterations in cancer; biomarker discovery; therapeutic strategies
Interests: metabolomics; chemical biology; drug discovery
Special Issue Information
Dear Colleagues,
Cancer cells undergo profound metabolic alterations to sustain their rapid proliferation, ensure their survival, and adapt to nutrient limitation conditions. While these metabolic alterations support cancer growth, they expose signatures that are highly different from those in healthy tissue. The identification of these metabolic pathways and tumour-derived metabolites released into the circulation enable the identification of both novel targets and tumour-specific biomarkers. This strategy holds promise in enhancing the translational potential of cancer research and advancing personalized treatment approaches.
This Special Issue will showcase contributions from authors with novel evidence highlighting the influence of cancer metabolism on both therapeutic strategies and biomarker discovery. We encourage contributions exploring how metabolic vulnerabilities can be targeted to disrupt tumour growth and induce apoptosis or ferroptosis, as well as how metabolite profiling can aid in the early detection and diagnosis of tumours. We also encourage contributions proposing methods to improve the detection of metabolites, as well as review articles and comments on the current landscape of cancer metabolism and metabolic biomarkers.
Potential topics include, but are not limited to, the following:
- Novel metabolic targets for cancer treatment;
- Novel links between cell signalling and metabolic pathways;
- Interactions between metabolic pathways and cell cycle progression;
- Role of metabolism in cell migration and invasion;
- New mechanistic insights into the connection between metabolism and apoptosis or ferroptosis;
- Novel methodologies to detect or improve the detection of polar and non-polar metabolites involved in cancer.
Dr. Victor H. Villar
Dr. Alejandro Huerta-Uribe
Dr. Ruhi Deshmukh
Guest Editors
Manuscript Submission Information
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Keywords
- cancer
- metabolic pathways
- apoptosis
- treatment
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